Perspectives in Primary Prevention Research for Breast Cancer: A Focus on Gene—Environment Interactions

Perspectives in Primary Prevention Research for Breast Cancer: A Focus on Gene—Environment Interactions PDF Author: Sophie A. Lelièvre
Publisher: Frontiers Media SA
ISBN: 2889666980
Category : Science
Languages : en
Pages : 156

Book Description


Gene-Environment Interaction and Breast Cancer on Long Island, NY.

Gene-Environment Interaction and Breast Cancer on Long Island, NY. PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 6

Book Description
This research project will build upon the Long Island Breast Cancer Study Project (LIBCSP), a large population-based, case-control study of the environment and breast cancer. Participants completed an in-person interviewer-administered interview, donated blood and urine samples, and had home environment samples (dust, soil, and water) collected. For this study, 200 cases and 200 controls who donated urine samples will be selected and their urine samples will be analyzed for a panel of environmental estrogen (EE) biomarkers. In addition, these same women will be screened for polymorphisms in both the estrogen receptor alpha and beta genes. Breast cancer risk in relation to the combination of these multiple EE exposures and gene-environment interactions will be investigated using sophisticated statistical methods, such as hierarchical regression models and factor analysis. Additionally, a pilot investigation of the correlation between EE levels in house dust and urinary biomarker levels will be conducted. Currently, samples for this study have been selected and the laboratory analyses are underway. Results of the proposed research project will be of enormous public health relevance since they may advance researchers' knowledge of modifiable breast cancer risk factors and newly identified EEs, thereby providing information that is essential for primary prevention.

Reducing Environmental Cancer Risk

Reducing Environmental Cancer Risk PDF Author: Suzanne H. Reuben
Publisher: DIANE Publishing
ISBN: 1437934218
Category : Health & Fitness
Languages : en
Pages : 240

Book Description
Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.

Contemporary Issues in Breast Cancer

Contemporary Issues in Breast Cancer PDF Author: Karen Hassey Dow
Publisher: Jones & Bartlett Learning
ISBN: 9780763714826
Category : Breast
Languages : en
Pages : 378

Book Description
Now in its second edition, Contemporary Issues in Breast Cancer addresses the significant changes that have occurred in breast cancer treatment in recent years. Completely revised and updated, the second edition offers current breast cancer findings and research interventions. The latest information on epidemiology, treatment, and symptom management is presented from a nursing perspective, and new chapters focus specifically on the treatment of recurrent and metastatic breast cancer. This unique book also explores survivorship and end of life in the context of the individual, family, and community, and provides insight into the role that culture and ethnicity play in understanding and treating breast cancer. Contemporary Issues in Breast Cancer, Second Edition is an indispensable resource for both oncology nurses and advanced practice nurses in medical and surgical oncology.

Environmental Health Perspectives

Environmental Health Perspectives PDF Author:
Publisher:
ISBN:
Category : Environmental health
Languages : en
Pages : 882

Book Description


Genes, Behavior, and the Social Environment

Genes, Behavior, and the Social Environment PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309101964
Category : Social Science
Languages : en
Pages : 385

Book Description
Over the past century, we have made great strides in reducing rates of disease and enhancing people's general health. Public health measures such as sanitation, improved hygiene, and vaccines; reduced hazards in the workplace; new drugs and clinical procedures; and, more recently, a growing understanding of the human genome have each played a role in extending the duration and raising the quality of human life. But research conducted over the past few decades shows us that this progress, much of which was based on investigating one causative factor at a time—often, through a single discipline or by a narrow range of practitioners—can only go so far. Genes, Behavior, and the Social Environment examines a number of well-described gene-environment interactions, reviews the state of the science in researching such interactions, and recommends priorities not only for research itself but also for its workforce, resource, and infrastructural needs.

Advancing the Science of Cancer in Latinos

Advancing the Science of Cancer in Latinos PDF Author: Amelie G. Ramirez
Publisher: Springer Nature
ISBN: 303029286X
Category : Medical
Languages : en
Pages : 320

Book Description
This open access book gives an overview of the sessions, panel discussions, and outcomes of the Advancing the Science of Cancer in Latinos conference, held in February 2018 in San Antonio, Texas, USA, and hosted by the Mays Cancer Center and the Institute for Health Promotion Research at UT Health San Antonio. Latinos – the largest, youngest, and fastest-growing minority group in the United States – are expected to face a 142% rise in cancer cases in coming years. Although there has been substantial advancement in cancer prevention, screening, diagnosis, and treatment over the past few decades, addressing Latino cancer health disparities has not nearly kept pace with progress. The diverse and dynamic group of speakers and panelists brought together at the Advancing the Science of Cancer in Latinos conference provided in-depth insights as well as progress and actionable goals for Latino-focused basic science research, clinical best practices, community interventions, and what can be done by way of prevention, screening, diagnosis, and treatment of cancer in Latinos. These insights have been translated into the chapters included in this compendium; the chapters summarize the presentations and include current knowledge in the specific topic areas, identified gaps, and top priority areas for future cancer research in Latinos. Topics included among the chapters: Colorectal cancer disparities in Latinos: Genes vs. Environment Breast cancer risk and mortality in women of Latin American origin Differential cancer risk in Latinos: The role of diet Overcoming barriers for Latinos on cancer clinical trials Es tiempo: Engaging Latinas in cervical cancer research Emerging policies in U.S. health care Advancing the Science of Cancer in Latinos proves to be an indispensable resource offering key insights into actionable targets for basic science research, suggestions for clinical best practices and community interventions, and novel strategies and advocacy opportunities to reduce health disparities in Latino communities. It will find an engaged audience among researchers, academics, physicians and other healthcare professionals, patient advocates, students, and others with an interest in the broad field of Latino cancer.

Multiple Primary Cancers

Multiple Primary Cancers PDF Author: Alfred I. Neugut
Publisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 504

Book Description
The purpose of this text is to help develop a better understanding of the nature of cancer, to expand prevention strategies, and to improve diagnostic and prognostic skills centred around multiple primary cancers. Clinical studies focusing on the aetiology of multiple primary cancers, statistical data presented in tables, and discussions on various organ sites and the possible occurrence of multiple primary cancers are addressed throughout the text. The first part reviews various methodological and statistical considerations in the study, management and prevention of primary, secondary and multiple primary cancers. An entire chapter contains tables of incidence rates of various multiple primary cancers that prove helpful in subsequent chapters. Part Two discusses predisposing genetic conditions and various forms of environmental factors that are associated with multiple primary cancers. Finally, the last section review selected types of cancers and focuses on possible clinical implications for occurrences of specific multiple primary cancers.

Physical Activity and Cancer

Physical Activity and Cancer PDF Author: Kerry S. Courneya
Publisher: Springer Science & Business Media
ISBN: 3642042317
Category : Medical
Languages : en
Pages : 389

Book Description
This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Theory at a Glance

Theory at a Glance PDF Author: Karen Glanz
Publisher:
ISBN:
Category : Health behavior
Languages : en
Pages : 52

Book Description