PDF/Textbook Partial Volume Correction For High Resolution Positron Emission Tomography Using Cortical Surface Information Full Download

Partial-volume Correction for High-resolution Positron Emission Tomography Using Cortical Surface Information

Author: Thomas Funck
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description
" Images from high resolution brain positron emission tomography (PET) scanners (CTI/Siemens HRRT) can measure differences in neuroreceptor concentrations in the gray matter that are related to cytoarchitectonic differences. However, the loss of resolution due to the PET imaging process results in partial-volume effects (PVE) that obscure the true radiotracer distribution. Although several partial-volume correction algorithms exist, these frequently require severely limiting assumptions. We developed a new iterative deconvolution algorithm for the partial-volume correction of PET images that aims to overcome the limitations of previous methods. The proposed method does so using two innovative techniques. One is the incorporation anatomic information from a cortical gray matter surface representation, extracted from magnetic resonance imaging (MRI). The second is the use of anatomically constrained smoothing to attenuate noise in the image. This method was validated using simulated and clinical data. The results show that our method consistently recovers accurate radiotracer concentrations on simulated data sets and produces similar, though slightly overestimated, results on the real clinical data when compared to the gold-standard partial-volume correction method. " --

Development of a Motion Correction and Partial Volume Correction Algorithm for High Resolution Imaging in Positron Emission Tomography

Author: Shailendra Hemun Segobin
Publisher:
ISBN:
Category :
Languages : en
Pages :

Book Description

Quantitative Functional Brain Imaging with Positron Emission Tomography

Author: Richard E. Carson
Publisher: Elsevier
ISBN: 0080540112
Category : Science
Languages : en
Pages : 535

Book Description
This book presents the latest scientific developments in the field of positron emission tomography (PET) dealing with data acquisition, image processing, applications, statistical analysis, tracer development, parameter estimation, and kinetic modeling. It covers improved methodology and the application of existing techniques to new areas. The text also describes new approaches in scanner design and image processing, and the latest techniques for modeling and statistical analyses. This volume will be a useful reference for the active brain PET scientist, as well as a valuable introduction for students and researchers who wish to take advantage of the capabilities of PET to study the normal and diseased brain. Authored by international authorities in PET Provides the latest up-to-date techniques and applications Covers all fundamental disciplines of PET in one volume A comprehensive resource for students, clinicians, and new PET researchers

MRI-Negative Epilepsy

Author: Elson L. So
Publisher: Cambridge University Press
ISBN: 110703423X
Category : Medical
Languages : en
Pages : 259

Book Description
This book critically appraises the role and value of specific diagnostic and treatment techniques for drug-resistant, MRI-negative epilepsy. The authors present the evidence and share their expertise on the diagnostic options and surgical approaches that make epilepsy surgery possible and worthwhile in this complex and challenging condition.

Medical Imaging Systems

Author: Andreas Maier
Publisher: Springer
ISBN: 3319965204
Category : Computers
Languages : en
Pages : 263

Book Description
This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.

PET/CT in Infection and Inflammation

Author: Thomas Wagner
Publisher: Springer
ISBN: 3319904124
Category : Medical
Languages : en
Pages : 112

Book Description
This pocket book provides clinicians with the necessary information to understand the role of FDG PET/CT in infection and inflammation. It will help both in making appropriate imaging requests with adequate clinical information and in interpreting the report. The coverage encompasses a wide range of topics, including the role of PET/CT in pyrexia of unknown origin, vasculitis, autoimmune diseases, prosthetic joint infections, osteomyelitis and diabetic foot, immunodeficiency disease, and vascular graft surgery. The book will be a very useful guide to a great test that can provide significant assistance in patient management. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, in which leading professionals succinctly explain the importance of nuclear medicine in the diagnosis and management of oncological and non-oncological conditions.

Basic Science of PET Imaging

Author: Magdy M. Khalil
Publisher: Springer
ISBN: 3319400703
Category : Medical
Languages : en
Pages : 621

Book Description
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.