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Author: Charlie Fletcher Publisher: Orbit ISBN: 0316279498 Category : Fiction Languages : en Pages : 487
Book Description
"Exciting, exhilaring, scary and moving in equal measure, The Oversight is a teeming world of dark deeds and dark magics, brilliantly realized." -- M. R. Carey The Oversight of London has been sworn for millennia to prevent the natural and the supernatural worlds from preying on each other. Now, at its lowest ebb, with its headquarters destroyed and its last members scattered far and wide, this secret society will battle for survival and face the harshest foe it has ever met: itself.
Author: Charlie Fletcher Publisher: Orbit ISBN: 0316279498 Category : Fiction Languages : en Pages : 487
Book Description
"Exciting, exhilaring, scary and moving in equal measure, The Oversight is a teeming world of dark deeds and dark magics, brilliantly realized." -- M. R. Carey The Oversight of London has been sworn for millennia to prevent the natural and the supernatural worlds from preying on each other. Now, at its lowest ebb, with its headquarters destroyed and its last members scattered far and wide, this secret society will battle for survival and face the harshest foe it has ever met: itself.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 030929665X Category : Medical Languages : en Pages : 78
Book Description
Gene transfer research is a rapidly advancing field that involves the introduction of a genetic sequence into a human subject for research or diagnostic purposes. Clinical gene transfer trials are subject to regulation by the U.S. Food and Drug Administration (FDA) at the federal level and to oversight by institutional review boards (IRBs) and institutional biosafety committees (IBCs) at the local level before human subjects can be enrolled. In addition, at present all researchers and institutions funded by the National Institutes of Health (NIH) are required by NIH guidelines to submit human gene transfer protocols for advisory review by the NIH Recombinant DNA Advisory Committee (RAC). Some protocols are then selected for individual review and public discussion. Oversight and Review of Clinical Gene Transfer Protocols provides an assessment of the state of existing gene transfer science and the current regulatory and policy context under which research is investigated. This report assesses whether the current oversight of individual gene transfer protocols by the RAC continues to be necessary and offers recommendations concerning the criteria the NIH should employ to determine whether individual protocols should receive public review. The focus of this report is on the standards the RAC and NIH should use in exercising its oversight function. Oversight and Review of Clinical Gene Transfer Protocols will assist not only the RAC, but also research institutions and the general public with respect to utilizing and improving existing oversight processes.
Book Description
This book examines the legal and policy issues surrounding congressional investigations through a series of case studies, with an emphasis on the second half of the twentieth century to date. The new and updated second edition covers significant developments from the Obama and Trump administrations, including the two Trump impeachments, the January 6 Committee investigation of the 2021 insurrection at the U.S. Capitol, and recent Supreme Court decisions on congressional investigative powers. The book is organized by case study topic, with each chapter using two or three case studies to introduce and analyze a discrete area of legal authorities and policy issues. The central thesis and organizing principle of the book is the importance of effective congressional oversight and investigative activities in our American democratic system of government, especially in the aftermath of the disputed 2020 presidential election. In addition to collecting legal authorities, the book includes relevant historical information and structural analysis of government functions, with an emphasis on separation of powers issues. The use of a case study format, rather than a traditional law school casebook format, is intended to present the subject matter in a way that can be used to teach undergraduate and graduate school courses as well as law school courses. The authors combine original congressional and judicial source materials with book excerpts and explanatory text, as well as notes and questions for each case study, to make the subject matter accessible to graduate and upper-level undergraduate students in government and political science courses, as well as to law students.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309164923 Category : Social Science Languages : en Pages : 216
Book Description
Ethical Considerations for Research on Housing-Related Health Hazards Involving Children explores the ethical issues posed when conducting research designed to identify, understand, or ameliorate housing-related health hazards among children. Such research involves children as subjects and is conducted in the home and in communities. It is often conducted with children in low-income families given the disproportionate prevalence of housing-related conditions such as lead poisoning, asthma, and fatal injuries among these children. This book emphasizes five key elements to address the particular ethical concerns raised by these characteristics: involving the affected community in the research and responding to their concerns; ensuring that parents understand the essential elements of the research; adopting uniform federal guidelines for such research by all sponsors (Subpart D of 45 CFR 46); providing guidance on key terms in the regulations; and viewing research oversight as a system with important roles for researchers, IRBs and their research institutions, sponsors and regulators of research, and the community.
Author: Charlie Fletcher Publisher: Little, Brown Books for Young Readers ISBN: 1423138007 Category : Juvenile Fiction Languages : en Pages : 484
Book Description
A city has many lives and layers. London has more than most. Not all the layers are underground, and not all the lives belong to the living. Twelve-year-old George Chapman is about to find this out the hard way. When, in a tiny act of rebellion, George breaks the head from a stone dragon outside the Natural History Museum, he awakes an ancient power. This power has been dormant for centuries but the results are instant and terrifying: A stone Pterodactyl unpeels from the wall and starts chasing George. He runs for his life but it seems that no one can see what he's running from. No one, except Edie, who is also trapped in this strange world. And this is just the beginning as the statues of London awake This is a story of statues coming to life; of a struggle between those with souls and those without; of how one boy who has been emotionally abandoned manages to find hope.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309132746 Category : Medical Languages : en Pages : 344
Book Description
Among the issues confronting America is long-term care for frail, older persons and others with chronic conditions and functional limitations that limit their ability to care for themselves. Improving the Quality of Long-Term Care takes a comprehensive look at the quality of care and quality of life in long-term care, including nursing homes, home health agencies, residential care facilities, family members and a variety of others. This book describes the current state of long-term care, identifying problem areas and offering recommendations for federal and state policymakers. Who uses long-term care? How have the characteristics of this population changed over time? What paths do people follow in long term care? The committee provides the latest information on these and other key questions. This book explores strengths and limitations of available data and research literature especially for settings other than nursing homes, on methods to measure, oversee, and improve the quality of long-term care. The committee makes recommendations on setting and enforcing standards of care, strengthening the caregiving workforce, reimbursement issues, and expanding the knowledge base to guide organizational and individual caregivers in improving the quality of care.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309071879 Category : Computers Languages : en Pages : 208
Book Description
The need for quality improvement and for cost saving are driving both individual choices and health system dynamics. The health services research that we need to support informed choices depends on access to data, but at the same time, individual privacy and patient-health care provider confidentiality must be protected.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309084881 Category : Medical Languages : en Pages : 313
Book Description
When 18-year-old Jesse Gelsinger died in a gene transfer study at the University of Pennsylvania, the national spotlight focused on the procedures used to ensure research participants' safety and their capacity to safeguard the well-being of those who volunteer for research studies. Responsible Research outlines a three-pronged approach to ensure the protection of every participant through the establishment of effective Human Research Participant Protection Programs (HRPPPs). The approach includes: Improved research review processes, Recognition and integration of research participants' contributions to the system, and Vigilant maintenance of HRPPP performance. Issues addressed in the book include the need for in-depth, complimentary reviews of science, ethics, and conflict of interest reviews; desired qualifications for investigators and reviewers; the process of informed consent; federal and institutional oversight; and the role of accreditation. Recommendations for areas of key interest include suggestions for legislative approaches, compensation for research-related injury, and the refocusing of the mission of institutional review boards. Responsible Research will be important to anyone interested in the issues that are relevant to the practice of using human subjects as research participants, but especially so to policy makers, research administrators, investigators, and research sponsorsâ€"but also including volunteers who may agree to serve as research participants.
Author: Charlie Fletcher
Author: Charlie Fletcher
Author: Institute of Medicine
Author: Carlos Closa
Author: Lance Cole (Law teacher)
Author: Institute of Medicine
Author: Charlie Fletcher
Author: Institute of Medicine
Author: Institute of Medicine
Author: Alexia Nalewaik
Author: Institute of Medicine