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Author: Tom Kinzel Publisher: Wiley-VCH ISBN: 9783527316656 Category : Science Languages : en Pages : 314
Book Description
Wie die beiden Vorgängerbände (Organic Sytnhesis Workbook I und II) erklärt dieses Arbeitsbuch Prinzipien der organischen Synthesechemie an Beispielen aus modernen, erfolgreichen Naturstoffsynthesen. Übersichtlich strukturiert in Schlüsselreaktionen und Detailerläuterungen, hilft der mit zahlreichen Querverweisen ausgestattete Band bei der selbstständigen Lösung von Syntheseproblemen.
Author: Tom Kinzel Publisher: Wiley-VCH ISBN: 9783527316656 Category : Science Languages : en Pages : 314
Book Description
Wie die beiden Vorgängerbände (Organic Sytnhesis Workbook I und II) erklärt dieses Arbeitsbuch Prinzipien der organischen Synthesechemie an Beispielen aus modernen, erfolgreichen Naturstoffsynthesen. Übersichtlich strukturiert in Schlüsselreaktionen und Detailerläuterungen, hilft der mit zahlreichen Querverweisen ausgestattete Band bei der selbstständigen Lösung von Syntheseproblemen.
Author: Christian Bittner Publisher: Wiley-VCH ISBN: Category : Science Languages : en Pages : 308
Book Description
Regular practice makes perfect - and this is equally true of organic synthesis. Only the numerous and constantly new little tricks and tips make for elegant synthesis. Knowledge of synthesis methods, reactivities, reagents, protective groups and much more is best acquired - and retained - by way of detailed analysis and processing of complex synthesis paths. This workbook allows students to easily test and strengthen their own chemical repertoire by way of sixteen new syntheses, including tricycles, macrolides, terpenes, and alkaloids. It follows the tried-and-tested concept used in the first volume, although each volume can be read independently of the other. It briefly describes all the target molecules and the relevant synthesis tasks, before going on to classify them into smaller sub-problems that may be solved by the reader using tips given in varying detail. In this way, readers can define the degree of difficulty for themselves. The solution section with comments and a comprehensive discussion of the key steps in reaction sequences and their actual application allows a simple check of the student's own strategy. An appendix with references to original syntheses and further literature rounds off the whole. Whether prior to an examination, for preparing seminars or for ideas in looking for synthesis strategies, every organic chemist - practicing and ongoing - will profit from reading this workbook.
Author: Jan-Arne Gewert Publisher: John Wiley & Sons ISBN: 3527301879 Category : Science Languages : en Pages : 291
Book Description
From the Foreword written by Erick M. Carreira: "... The Organic Synthesis Workbook is an ideal compilation of state-of-the art modern syntheses which wonderfully showcases the latest advances in synthetic chemistry in combination with fundamentals in a question-and-answer format. The structure of the book is such that the reader can appreciate the intricacies of strategic planning, reagent tailoring, and structural analysis within the context of the individual synthetic targets. In providing highlights of synthesis from a wider range of natural products classes (alkaloids, terpenes, macrolides) the reader is given a tour through a broad range of reaction chemistry and concepts. Moreover, because in its scope the authors have ignored international borders, the book effectively parlays the global aspect of current research in the exciting field of organic synthesis... The Organic Synthesis Workbook promises to be to the current generation of graduate students, and even "students-for-life", what Ireland's and Alonso's books were to those of us who were graduate students in the 80's [Alsono: The Art of Problem Solving in Organic Chemistry, Ireland: Organic Synthesis]. The authors have wonderfully captured the thrill, the enjoyment, and the intellectual rigor that is so characteristic of modern synthetic organic chemistry."
Author: Paul Wyatt Publisher: John Wiley & Sons ISBN: 1118681444 Category : Science Languages : en Pages : 55
Book Description
Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren's bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. * A comprehensive, practical account of the key concepts involved in synthesising compounds * Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations * Focuses on reactions that really work rather than those with limited application * Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.
Author: Michael Smith Publisher: Academic Press ISBN: 0124158846 Category : Science Languages : en Pages : 1537
Book Description
A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined. To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to ‘disconnect’ a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader’s understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists. The book is intended for graduate and postgraduate students, scientific researchers in chemistry New publisher, new edition; extensively updated and corrected Over 950 new references with more than 6100 references in total Over 600 new reactions and figures replaced or updated Over 300 new homework problems from the current literature to provide nearly 800 problems to test reader understanding of the key principles
Author: K. C. Nicolaou Publisher: John Wiley & Sons ISBN: 3527292314 Category : Science Languages : en Pages : 826
Book Description
K.C. Nicolaou - Winner of the Nemitsas Prize 2014 in Chemistry This book is a must for every synthetic chemist. With didactic skill and clarity, K. C. Nicolaou and E. Sorensen present the most remarkable and ingenious total syntheses from outstanding synthetic organic chemists. To make the complex strategies more accessible, especially to the novice, each total synthesis is analyzed retrosynthetically. The authors then carefully explain each synthetic step and give hints on alternative methods and potential pitfalls. Numerous references to useful reviews and the original literature make this book an indispensable source of further information. Special emphasis is placed on the skillful use of graphics and schemes: Retrosynthetic analyses, reaction sequences, and stereochemically crucial steps are presented in boxed sections within the text. For easy reference, key intermediates are also shown in the margins. Graduate students and researchers alike will find this book a gold mine of useful information essential for their daily work. Every synthetic organic chemist will want to have a copy on his or her desk.
Author: Pierre Vogel Publisher: John Wiley & Sons ISBN: 3527345329 Category : Science Languages : en Pages : 1382
Book Description
Provides the background, tools, and models required to understand organic synthesis and plan chemical reactions more efficiently Knowledge of physical chemistry is essential for achieving successful chemical reactions in organic chemistry. Chemists must be competent in a range of areas to understand organic synthesis. Organic Chemistry provides the methods, models, and tools necessary to fully comprehend organic reactions. Written by two internationally recognized experts in the field, this much-needed textbook fills a gap in current literature on physical organic chemistry. Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry. Subsequent chapters demonstrate various reactions involving organic, organometallic, and biochemical reactants and catalysts. Throughout the text, numerous questions and exercises, over 800 in total, help readers strengthen their comprehension of the subject and highlight key points of learning. The companion Organic Chemistry Workbook contains complete references and answers to every question in this text. A much-needed resource for students and working chemists alike, this text: -Presents models that establish if a reaction is possible, estimate how long it will take, and determine its properties -Describes reactions with broad practical value in synthesis and biology, such as C-C-coupling reactions, pericyclic reactions, and catalytic reactions -Enables readers to plan chemical reactions more efficiently -Features clear illustrations, figures, and tables -With a Foreword by Nobel Prize Laureate Robert H. Grubbs Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis is an ideal textbook for students and instructors of chemistry, and a valuable work of reference for organic chemists, physical chemists, and chemical engineers.
Author: Robert J. Ouellette Publisher: Elsevier ISBN: 0128010827 Category : Science Languages : en Pages : 1241
Book Description
Organic Chemistry provides a comprehensive discussion of the basic principles of organic chemistry in their relation to a host of other fields in both physical and biological sciences. This book is written based on the premise that there are no shortcuts in organic chemistry, and that understanding and mastery cannot be achieved without devoting adequate time and attention to the theories and concepts of the discipline. It lays emphasis on connecting the basic principles of organic chemistry to real world challenges that require analysis, not just recall. This text covers topics ranging from structure and bonding in organic compounds to functional groups and their properties; identification of functional groups by infrared spectroscopy; organic reaction mechanisms; structures and reactions of alkanes and cycloalkanes; nucleophilic substitution and elimination reactions; conjugated alkenes and allylic systems; electrophilic aromatic substitution; carboxylic acids; and synthetic polymers. Throughout the book, principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the text and real world applications. There are extensive examples of biological relevance, along with a chapter on organometallic chemistry not found in other standard references. This book will be of interest to chemists, life scientists, food scientists, pharmacists, and students in the physical and life sciences. Contains extensive examples of biological relevance Includes an important chapter on organometallic chemistry not found in other standard references Extended, illustrated glossary Appendices on thermodynamics, kinetics, and transition state theory
Author: Stuart Warren Publisher: John Wiley & Sons ISBN: 9780471996125 Category : Science Languages : en Pages : 298
Book Description
Teaches students to use the language of sythesis directly (utilizing the grammar of synthon and disconnection) rather than translating it into that of organic chemistry.
Author: Tom Kinzel
Author: Tom Kinzel
Author: T. Kinzel Raith, C. (Major, F.)
Author: Christian Bittner
Author: Jan-Arne Gewert
Author: Paul Wyatt
Author: Michael Smith
Author: K. C. Nicolaou
Author: Pierre Vogel
Author: Robert J. Ouellette
Author: Stuart Warren