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Author: David J Hart Publisher: World Scientific ISBN: 9814464562 Category : Science Languages : en Pages : 589
Book Description
This book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products.The book provides readers with a somewhat historical overview of organic and natural products chemistry, and spans synthetic methodology that dates from the 1940's to the present time. It is written in a style that readers will find entertaining at times. It also contains lots of useful references with complete titles provided.
Author: David J Hart Publisher: World Scientific ISBN: 9814464562 Category : Science Languages : en Pages : 589
Book Description
This book is written for advanced graduate and undergraduate students to expose them to a variety of strategies for the synthesis of organic compounds. This is done largely within the context of natural products synthesis, but some unnatural products synthesis is also included. Multiple approaches to each group of synthesis targets are presented, and the approaches are compared with one another with an eye on similarities and differences. General problems in organic synthesis (for example, strategies for the preparation of 6-membered rings and 5-membered rings, the importance of oxidation state, the problem of acyclic diastereoselectivity, the problem of controlling absolute stereochemistry, the importance of functional group relationships) are introduced early in the book and revisited throughout the text within the context of a variety of structurally unrelated natural products.The book provides readers with a somewhat historical overview of organic and natural products chemistry, and spans synthetic methodology that dates from the 1940's to the present time. It is written in a style that readers will find entertaining at times. It also contains lots of useful references with complete titles provided.
Author: Tomas Hudlicky Publisher: Wiley-VCH ISBN: Category : Science Languages : en Pages : 1032
Book Description
This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)
Author: Jie Jack Li Publisher: Springer Science & Business Media ISBN: 3642340652 Category : Science Languages : en Pages : 292
Book Description
'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.
Author: Tse-Lok Ho Publisher: John Wiley & Sons ISBN: 1118523881 Category : Science Languages : en Pages : 664
Book Description
The highly successful Fieser & Fieser series has provided several generations of professional chemists and students with an timely survey of the reagent literature. Providing an up-to-date, A-to-Z listing of reagents cited in synthetic literature, Fiesers' Reagents for Organic Synthesis, Volume 27 encompasses chemical literature from the end of 2009 to the end of 2011. Listed by common name, each entry feature a concise description, illustrations of chemical reactions, selected examples of applications, how to make it or buy it, what it is good for, and where to find complete details.
Author: John ApSimon Publisher: Wiley-Interscience ISBN: 9780471054603 Category : Science Languages : en Pages : 638
Book Description
The Vocabulary of Organic Chemistry Milton Orchin, Fred Kaplan,Roger S. Macomber, R. Marshall Wilson & Hans W. ZimmerIdentifies those terms and concepts which now constitute thevocabulary of organic chemists, then defines and explains theseterms and concepts, most often using examples. Organized so thatsubject matter builds successively on increasingly varied andcomplex material. All terms and concepts related to a particulararea are placed together, except for one chapter on name and typereactions, which is alphabetically arranged. The only book of itskind--valuable to students, teachers and chemical professionalsalike. 1980 Protective Groups in Organic Synthesis Theodora W.Greene Provides essential information on transformations of organicmolecules, including instructions and references for the protectionand regeneration of the major organic functional groups: -OH, -NH,-SH, -COOH, and C = O. Covers the best methods of formation andcleavage, properties of protective groups, selection of a group fora particular need. Organization is by functional groups to beprotected, with groups arranged in order of increasing complexityof structure, and with most efficient methods of formation orcleavage described first. Charts show the reactivities of 270 ofthe most commonly used protective groups to 108 reagents, selectedas prototypes for the entire array of reagents available to theorganic chemist. 1981 Basics of Electroorganic Synthesis DemetriosK. Kyriacou A veteran organic electrochemist illuminatesfundamental ideas and principles by means of selected examples fromthe literature and his own research, demonstrating the practicalunity of the field in a clear, concise manner. Describes thegeneral electroorganic reaction and illustrates the general mode ofconcepts and applications in the area of electrosynthesis. Containsa brief survey of electroorganic reactions and coverage of specialtopics and the praxis of electroorganic synthesis. 1981
Author: John ApSimon Publisher: Wiley-Interscience ISBN: 047012959X Category : Science Languages : en Pages : 720
Book Description
The Total Synthesis of Natural Products Volume Seven Edited by John ApSimon This volume contains a chapter updating monoterpene synthesis and reviews the newer areas of leukotrienes and macrocyclic lactones. 1988 (0 471-88076-0) 480 pp. The Total Synthesis of Natural Products Volume Six Edited by John ApSimon Volume Six considers the total synthesis of triterpenes, carbohydrates, aromatic steroids, pyrrole pigments, and genes. 1984 (0 471-09900-7) 304 pp. The Total Synthesis of Natural Products Volume Five Edited by John ApSimon This present volume considers the total syntheses of sesquiterpenes, reflecting, in part, the heightened research activity in this area. 1983 (0 471-09808-6) 560 pp. The Total Synthesis of Natural Products Volume Four Edited by John ApSimon The fourth volume in this successful series offers synthetic approaches to a wide variety of natural products, including the synthesis of cannabinoids, natural inophores, insect pheromones, monoterpenes, and prostaglandins. 1981 (0 471-05460-7) 624 pp. The Total Synthesis of Natural Products Volume Three Edited by John ApSimon 1977 (0 471-02392-2) 576 pp. The Total Synthesis of Natural Products Volume Two Edited by John ApSimon 1973 (0 471-03252-2) 768 pp. The Total Synthesis of Natural Products Volume One Edited by John ApSimon 1973 (0 471-03251-4) 624 pp.
Author: F. Serratosa Publisher: Elsevier Science ISBN: 9780444819352 Category : Science Languages : en Pages : 539
Book Description
The first edition of this book was welcomed with great enthusiasm by teachers and students. It therefore seemed opportune to publish a second, revised, updated and extended edition. Unfortunately, Professor Fèlix Serratosa died before he could complete this task. Some new material has been added, the more significant changes being:. The book has been restructured into two well-differentiated sections: Part A, dealing with conventional organic synthesis, and Part B, devoted exclusively to computer-assisted organic synthesis and based on the former Chapter 11 and Appendices 2, 3 and 4 of the first edition. As decided in advance, Part B was to be the sole responsibility of Dr. Josep Xicart, who prepared the first versions of the CHAOS (Computerisation and Heuristics Applied to Organic Synthesis) program under the direction of Professor Serratosa.
Author: Hitosi Nozaki Publisher: Elsevier ISBN: 148327912X Category : Science Languages : en Pages : 441
Book Description
Current Trends in Organic Synthesis is a collection of papers presented at the Fourth International Conference on Organic Synthesis, held in Tokyo, Japan on August 22-27, 1982. This conference brings together the significant achievements in the diversified frontier fields of organic synthesis. This book is composed of 33 chapters. The first chapters focus on the synthesis of biologically active natural compounds, including metabolites of arachidonic acid, erythromycin A, verrucarins, steroids, anthracyclines, terpenes, yeast alanine t-RNA, beta-lactam antibiotics, and palitoxin. Other chapters deal with the central problems in stereoselective and chiral synthesis, as well as processes of high degree of stereochemical control and asymmetric induction. These chapters also describe chiral pool synthesis by means of carbohydrate precursors. This book also examines the methodologies in organic synthesis using reagents with boron, aluminum, transition metals, silicon, phosphorus, and sulfur. The remaining chapters are devoted to reactions involving radical initiated ring closure, small ring hydrogenolysis, annulene synthesis, vicarious nucleophilic substitution of aromatic hydrogen, and dichlorine monoxide mediated powerful chlorination. This book is of value to organic chemists and allied scientists.
Author: Paul M. Dewick Publisher: John Wiley & Sons ISBN: 9780471496410 Category : Medical Languages : en Pages : 524
Book Description
This guide covers classes of natural products in medicine, whether derived from plants, micro-organisms or animals. Structured according to biosynthetic pathway, it is written from a chemistry-based approach.
Author: David J Hart
Author: David J Hart
Author: Tomas Hudlicky
Author: Jie Jack Li
Author: Tse-Lok Ho
Author: Stephen Hanessian
Author: John ApSimon
Author: John ApSimon
Author: F. Serratosa
Author: Hitosi Nozaki
Author: Paul M. Dewick