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Ongoing Research in Jawed Fish Immunity: Structural and Functional Studies at the Protein and Cellular Levels

Ongoing Research in Jawed Fish Immunity: Structural and Functional Studies at the Protein and Cellular Levels PDF Author: Monica Imarai
Publisher: Frontiers Media SA
ISBN: 288963731X
Category :
Languages : en
Pages : 256

Book Description
Knowledge of jawed fish immune systems obtained in the last 15 years has been mostly obtained through the sequencing of genomes of different fish species and from the use of high-throughput techniques such as transcriptomic analysis and RNA sequencing, which has allowed characterization of immune gene responses at the transcriptomic level. Although these have been important tools for exploring the complexities of the immune responses of fish species, the next generation of knowledge requires the use of new tools and methods capable of unveiling the diversity of immune cells and molecules in jawed fish, the network of interactions and responses, and the mechanisms leading to immune protection against pathogens. For more than 10 years, many laboratories have been engaged in developing antibodies against key molecules of jawed fish immune systems in several different species because the lack of sequence conservation of most immune genes makes it impossible to use the large panel of antibodies against mammalian molecules for recognition of fish molecules. The numerous genes encoding cytokines and receptors have now been used to make recombinant proteins available, allowing studies of the complex network of cytokine and receptor functions central to fish immune responses. From many laboratories, new and interesting knowledge about immune cells, their functions and interactions can be studied with the availability of new tools and methods have begun to provide a clear understanding fish immunity at the protein and cellular levels. This Research Topic gives a comprehensive overview of the current knowledge of jawed fish immune responses with a particular emphasis on structural and functional studies at the protein and cellular levels.

Ongoing Research in Jawed Fish Immunity: Structural and Functional Studies at the Protein and Cellular Levels

Ongoing Research in Jawed Fish Immunity: Structural and Functional Studies at the Protein and Cellular Levels PDF Author: Monica Imarai
Publisher: Frontiers Media SA
ISBN: 288963731X
Category :
Languages : en
Pages : 256

Book Description
Knowledge of jawed fish immune systems obtained in the last 15 years has been mostly obtained through the sequencing of genomes of different fish species and from the use of high-throughput techniques such as transcriptomic analysis and RNA sequencing, which has allowed characterization of immune gene responses at the transcriptomic level. Although these have been important tools for exploring the complexities of the immune responses of fish species, the next generation of knowledge requires the use of new tools and methods capable of unveiling the diversity of immune cells and molecules in jawed fish, the network of interactions and responses, and the mechanisms leading to immune protection against pathogens. For more than 10 years, many laboratories have been engaged in developing antibodies against key molecules of jawed fish immune systems in several different species because the lack of sequence conservation of most immune genes makes it impossible to use the large panel of antibodies against mammalian molecules for recognition of fish molecules. The numerous genes encoding cytokines and receptors have now been used to make recombinant proteins available, allowing studies of the complex network of cytokine and receptor functions central to fish immune responses. From many laboratories, new and interesting knowledge about immune cells, their functions and interactions can be studied with the availability of new tools and methods have begun to provide a clear understanding fish immunity at the protein and cellular levels. This Research Topic gives a comprehensive overview of the current knowledge of jawed fish immune responses with a particular emphasis on structural and functional studies at the protein and cellular levels.

Origin and Evolution of the Vertebrate Immune System

Origin and Evolution of the Vertebrate Immune System PDF Author: L. Du Pasquier
Publisher: Springer Science & Business Media
ISBN: 3642596746
Category : Medical
Languages : en
Pages : 324

Book Description
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.

Fish Diseases

Fish Diseases PDF Author: Galina Jeney
Publisher: Academic Press
ISBN: 012804585X
Category : Technology & Engineering
Languages : en
Pages : 280

Book Description
Fish Diseases: Prevention and Control Strategies provides essential information on disease prevention and treatment by the most experienced fish culturists in the industry. The book presents both traditional and novel methodologies of identifying and addressing fish disease risk, along with preventative and responsive insights to the challenges impacting fish production today. Both specific (vaccination) and non-specific (immunostimulation) approaches are explored, from maintaining optimal environmental conditions, to understanding how stressors in fish affect their immune system. - Includes relevant information on government restrictions on drug usage in aquaculture to address the strict demand for fish products free of pollutants/antibiotics - Presents best practices in fish farming to prevent disease and promote good health status and fish disease management - Provides the most recent research on fish diseases prevention, the pathogens most studied, and options for methods of treatment

Immunoproteins—Advances in Research and Application: 2012 Edition

Immunoproteins—Advances in Research and Application: 2012 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1464996288
Category : Medical
Languages : en
Pages : 264

Book Description
Immunoproteins—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunoproteins. The editors have built Immunoproteins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunoproteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Immunoproteins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Fish Immune System: Organism, Pathogen, and Environment

The Fish Immune System: Organism, Pathogen, and Environment PDF Author:
Publisher: Academic Press
ISBN: 0080585396
Category : Science
Languages : ru
Pages : 395

Book Description
This book comprehensively reviews the immunology of fish--their health, interactions between them and their pathogens, and the impact of both endogenous and environmental changes on these interactions. Leading authorities provide an essential foundation for the understanding of fish immunology and fish health.As fish are increasingly used as model systems for vertebrate immune systems, The Fish Immune System will be a crucial reference. - The only comprehensive, single-volume reference on the fish immune system - Contributions from an international team of experts - Useful to researchers interested in fish health as well as professionals managing fish hatcheries, aquariums, and other facilities that must maintain healthy fish

Fish Defenses Vol. 2

Fish Defenses Vol. 2 PDF Author: Giacomo Zaccone
Publisher: CRC Press
ISBN: 0429526598
Category : Science
Languages : en
Pages : 261

Book Description
Dramatic changes in the environment, including habitat degradation and climate change, have focused attention on how individuals and populations respond to a shifting biotic and abiotic landscape. A critical step toward meeting this goal is a clear understanding of the capacity of individuals to defend themselves against threats. Changes in water q

The Fish Oocyte

The Fish Oocyte PDF Author: Patrick J. Babin
Publisher: Springer Science & Business Media
ISBN: 1402062354
Category : Science
Languages : en
Pages : 513

Book Description
This book presents a comprehensive overview on egg production in fish, from the standpoint of the oocyte. It covers oocyte development, maturation, hydration and fertilization. The book places special emphasis on using state-of-the-art tools for discerning the ultra-structure of the follicle and genomic/proteomic tools to fully understand biological basis of fish reproduction.

Aging and the Immune Response

Aging and the Immune Response PDF Author: Edmond A. Goidl
Publisher: Marcel Dekker
ISBN:
Category : Medical
Languages : en
Pages : 392

Book Description


Molecular Biology of B Cells

Molecular Biology of B Cells PDF Author: Tasuku Honjo
Publisher: Elsevier
ISBN: 0080479502
Category : Medical
Languages : en
Pages : 629

Book Description
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.

Chemosensory Transduction

Chemosensory Transduction PDF Author: Frank Zufall
Publisher: Academic Press
ISBN: 0128017864
Category : Science
Languages : en
Pages : 432

Book Description
Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University's Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals. - Provides a comprehensive overview for all chemosensory transduction mechanisms - Valuable for academics focused on sensory biology, neurobiology, and chemosensory transduction, as well as industry researchers in new flavor, fragrance, and food testing - Edited by leading experts in the field of olfactory transduction - Focuses on mammals, but lower vertebrates and invertebrate model systems are also included