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Author: Mark A. Geyer Publisher: Springer ISBN: 9783642257599 Category : Medical Languages : en Pages : 458
Book Description
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Author: Mark A. Geyer Publisher: Springer ISBN: 9783642257599 Category : Medical Languages : en Pages : 458
Book Description
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Author: Mark A. Geyer Publisher: Springer Science & Business Media ISBN: 3642257585 Category : Medical Languages : en Pages : 456
Book Description
This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Author: Mark A. Geyer Publisher: Springer Science & Business Media ISBN: 3642257577 Category : Medical Languages : en Pages : 456
Book Description
This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume will concentrate on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.
Author: Philip D. Harvey Publisher: Cambridge University Press ISBN: 1107013208 Category : Medical Languages : en Pages : 341
Book Description
Provides state-of-the-art information about cognition in schizophrenia with a wide ranging focus on measuring and treating cognitive deficits.
Author: Gerhard Gross Publisher: Springer Science & Business Media ISBN: 3642257615 Category : Medical Languages : en Pages : 423
Book Description
Six decades after the serendipitous discovery of chlorpromazine as an antipsychotic and four decades after the launch of clozapine, the first atypical or second generation antipsychotic, psychopharmacology has arrived at an important crossroad. It is clear that pharmacological research and pharmaceutical development must now focus on complementary or even alternative mechanisms of action to address unmet medical needs, i.e. poorly treated domains of schizophrenia, improved acceptance by patients, better adherence to medication, safety in psychoses in demented patients, and avoiding cardiac and metabolic adverse effects. The first completely novel mechanisms evolving from our insights into the pathophysiology of psychotic disorders, especially the role of glutamatergic mechanisms in schizophrenia, are now under development, and further principles are on the horizon. This situation, in many respects similar to that when the initial second-generation antipsychotics became available, can be rewarding for all. Preclinical and clinical researchers now have the opportunity to confirm their hypotheses and the pharmaceutical industry may be able to develop really novel classes of therapeutics. When we were approached by the publishers of the Handbook of Experimental Pharmacology to prepare a new volume on antipsychotics, our intention was to capture both, the accumulated preclinical and clinical knowledge about current antipsychotics as well as prospects for new and potentially more specific antischizophrenia principles. These efforts should be based on the pathophysiology of the diseases and the affected neurotransmitter systems. Since preclinical research on antipsychotic compounds is only reliable when intimately linked through translational aspects to clinical results, we decided to include clinical science as well. It turned out that that this endeavor could not be covered by a single volume. We thank the editorial board and the publishers for supporting our decision to prepare two volumes: Current Antipsychotics and Novel Antischizophrenia Treatments. These topics cannot really be separated from one another and should be seen as a composite entity despite the somewhat arbitrary separation of contributions into two volumes. The continuing challenges of developing improved and safer antipsychotic medications remain of concern and are discussed in the first volume. The new opportunities for the field to develop and license adjunctive treatments for the negative symptoms and cognitive deficits that are treated inadequately by existing compounds have been incentivized recently and provide the focus for the second volume. We hope these collective contributions will facilitate the development of improved treatments for the full range of symptomatology seen in the group of schizophrenias and other major psychotic disorders. Gerhard Gross, Ludwigshafen, Germany Mark A. Geyer, La Jolla, CA This volume will try to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters will also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. Non-schizophrenia indications will be covered to some extent, but not exhaustively.
Author: James M. Ritter Publisher: Elsevier Health Sciences ISBN: 0702054976 Category : Medical Languages : en Pages : 785
Book Description
For 25 years, Rang and Dale’s Pharmacology has delivered the core basic and clinical science information required by students and healthcare practitioners worldwide. Authors H. P. Rang, J. M. Ritter, R. J. Flower, and G. Henderson have ensured that the 8th Edition of this easy-to-read, comprehensive text continues the tradition of excellence with new coverage of drugs affecting the skin and new components online at studentconsult.com. Consult this title on your favorite e-reader. Get the essential pharmacology information you need from one authoritative source with an outstanding global reputation for excellence. Progress confidently through all relevant aspects of pharmacology, beginning with a molecular understanding of receptors and drug actions through clinical uses of key groups of drugs. Find important content quickly thanks to a color-coded layout that enables easy navigation and cross-referencing. Master difficult concepts with Key Points boxes, Clinical Uses boxes, and full-color illustrations throughout. Stay up to date with new information in the field, including an all-new chapter on drugs that affect the skin. Take advantage of new and unique features online, including 500+ chapter-specific multiple choice questions for immediate self-assessment. eBook version included! For the first time, you can access the entire book online or offline across all devices with the Student Consult eBook!
Author: Morton A. Heller Publisher: Psychology Press ISBN: 1135619301 Category : Psychology Languages : en Pages : 395
Book Description
Research on touch and blindness has undergone rapid transformation in recent years, with dramatic developments in technology designed to provide assistance to those who are blind, and advancements in robotics that demand haptic interfaces. Touch and Blindness approaches the study of the topic from the perspectives of psychological methodology and the most sophisticated, state-of-the-art techniques in neuroscience. This book, edited by well-known leaders in the field, is derived from the discussions presented by speakers at a conference held in 2002, and presents current research in the field. The book is arranged in a logical, disciplinary fashion, first discussing touch and blindness from a psychological perspective, followed by an examination from the perspective of neuroscience. Some specific topics include: *processing spatial information from touch and movement; *form, projection, and pictures for the blind; *neural substrate and visual and tactile object representations; and *the role of visual cortex in tactile processing. Touch and Blindness is ideal for researchers in psychology and neuroscience, medicine, and special education.
Author: Rudi A.J.O. Dierckx Publisher: Springer Nature ISBN: 3030572315 Category : Medical Languages : en Pages : 1075
Book Description
This book provides a comprehensive overview of the use of PET and SPECT in the classic psychiatric disorders such as depression, bipolar disorder, anxiety disorders, and schizophrenia. In addition, it discusses the application of these functional neuroimaging techniques in a variety of other conditions, including sleep disorders, eating disorders, autism, and chronic fatigue syndrome. The new edition has been extensively revised and updated to reflect the latest advances and results in nuclear imaging within the field. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be of value for all who have an interest in the field of neuroscience, from psychiatrists and radiologists/nuclear medicine specialists to interested general practitioners and cognitive psychologists. Companion volumes on the use of PET and SPECT in neurology and for the imaging of neurobiological systems complete a trilogy.
Author: Prasad, Barre Vijaya Publisher: IGI Global ISBN: 1522505202 Category : Medical Languages : en Pages : 435
Book Description
Although the epidemiology of mental illnesses is innately complex, there have been many strides in the diagnosis and treatment of chronic mental illnesses as more research is being conducted in the field. As more information becomes available, mental health professionals are able to develop more effective plans for caring for their patients. Chronic Mental Illness and the Changing Scope of Intervention Strategies, Diagnosis, and Treatment examines emergent research on the identification and epidemiology of various mental illnesses. Featuring information on the prevalence of the disease, psychopharmacological advancements, and strategies for the management of chronic mental illnesses, this book is ideally suited for students, psychiatrists, psychologists, neurologists, social workers, rehabilitation therapists, and other health professionals interested in learning more about shifting practices in the mental health sector.
Author: Mark A. Geyer
Author: Mark A. Geyer
Author: Mark A. Geyer
Author: Mark A. Geyer
Author: Philip D. Harvey
Author: Gerhard Gross
Author: James M. Ritter
Author: André Schmidt
Author: Morton A. Heller
Author: Rudi A.J.O. Dierckx
Author: Prasad, Barre Vijaya