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NMDA Antagonists as Potential Analgesic Drugs

NMDA Antagonists as Potential Analgesic Drugs PDF Author: Dalip J.S. Sirinathsinghji
Publisher: Birkhäuser
ISBN: 3034881398
Category : Medical
Languages : en
Pages : 212

Book Description
There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involved in the transmission of nociceptive information and in the triggering mechanisms for hyperalgesia and allodynia. This evidence allows rational development of a new class of analgesic drugs that act as antagonists of the NMDA receptor, supported by emerging evidence with existing excitatory amino acid antagonists. Leading scientists in excitatory amino acid and analgesia research have compiled in this volume the most recent information on molecular biology, physiology and pharmacology of NMDA receptors, their neuroanatomical localisation within specific neural pathways involved in nociception, and experimental and clinical evidence demonstrating the potential of receptor antagonists of NMDA and other excitatory amino acids in the treatment of pain states.

NMDA Antagonists as Potential Analgesic Drugs

NMDA Antagonists as Potential Analgesic Drugs PDF Author: Dalip J.S. Sirinathsinghji
Publisher: Birkhäuser
ISBN: 3034881398
Category : Medical
Languages : en
Pages : 212

Book Description
There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involved in the transmission of nociceptive information and in the triggering mechanisms for hyperalgesia and allodynia. This evidence allows rational development of a new class of analgesic drugs that act as antagonists of the NMDA receptor, supported by emerging evidence with existing excitatory amino acid antagonists. Leading scientists in excitatory amino acid and analgesia research have compiled in this volume the most recent information on molecular biology, physiology and pharmacology of NMDA receptors, their neuroanatomical localisation within specific neural pathways involved in nociception, and experimental and clinical evidence demonstrating the potential of receptor antagonists of NMDA and other excitatory amino acids in the treatment of pain states.

The Essence of Analgesia and Analgesics

The Essence of Analgesia and Analgesics PDF Author: Raymond S. Sinatra
Publisher: Cambridge University Press
ISBN: 1139491989
Category : Medical
Languages : en
Pages : 551

Book Description
The Essence of Analgesia and Analgesics is an invaluable practical resource for clinicians giving pain relief in any clinical setting, describing the pharmacologic principles and clinical use of all available pain medications. As well as detailed overviews of pain processing and analgesic theory, sections are dedicated to oral and panteral opioid analgesics, neuraxial opioids, NSAIDs, local anesthetics, anticonvulsant type analgesics, NMDA antagonists, alpha adrenergic analgesics, antidepressant analgesics, muscle relaxants, adjuvant medications, and new and emerging analgesics. The concise format of the chapters allows for quick and easy reading and assimilation of information. Enhanced by summary tables and figures, each chapter provides an overview of a particular drug, covering chemical structure, mode of activity, indications, contraindications, common doses and uses, advantages and disadvantages, and drug related adverse events. Key references are also provided. Edited by leading experts in pain management, this is essential reading for any clinician involved in pain management.

Anesthesiology In-Training Exam Review

Anesthesiology In-Training Exam Review PDF Author: Ratan K. Banik
Publisher: Springer
ISBN: 9783030872656
Category : Medical
Languages : en
Pages : 395

Book Description
Focused on rotations in regional anesthesia and chronic pain, this book provides a structured review of the concepts covered in the American Board of Anesthesiology in-training exam. The first section of the book covers regional anesthesia with dedicated chapters on basic science, acute postoperative pain, and nerve blocks for neuraxial, lower and upper extremity blocks, and head and neck. The second section on chronic pain includes chapters on basic science and common pain conditions - including craniofacial pain, CRPS, neuropathic pain, and cancer pain. This section closes on multimodal analgesia and other treatment approaches. Each chapter presents a common clinical topic and is organized by indications, preparation, technique, complication, prevention, clinical pearls, and related ABA key points. Highlights must-know information in bold throughout the text. Concise, practical, and easy-to-read, this book will aid anesthesiology residents, certified nurse anesthetists, and medical students in their study regarding patient care practices on regional anesthesia and chronic pain. The book will also be useful to residents going into regional anesthesia and pain medicine subspecialties during the year of their anesthesiology training.

Fundamentals of Anaesthesia

Fundamentals of Anaesthesia PDF Author: Colin Pinnock
Publisher: Cambridge University Press
ISBN: 9780521690799
Category : Medical
Languages : en
Pages : 990

Book Description
The second edition of Fundamentals of Anaesthesia builds upon the success of the first edition, and encapsulates the modern practice of anaesthesia in a single volume. Written and edited by a team of expert contributors, it provides a comprehensive but easily readable account of all of the information required by the FRCA Primary examination candidate and has been expanded to include more detail on all topics and to include new topics now covered in the examination. As with the previous edition, presentation of information is clear and concise, with the use of lists, tables, summary boxes and line illustrations where necessary to highlight important information and aid the understanding of complex topics. Great care has been taken to ensure an unrivalled consistency of style and presentation throughout.

Oxford Textbook of Palliative Medicine

Oxford Textbook of Palliative Medicine PDF Author: Nathan I. Cherny
Publisher: Oxford University Press, USA
ISBN: 0199656096
Category : Medical
Languages : en
Pages : 1281

Book Description
Emphasising the multi-disciplinary nature of palliative care the fourth edition of this text also looks at the individual professional roles that contribute to the best-quality palliative care.

Moderate and Deep Sedation in Clinical Practice

Moderate and Deep Sedation in Clinical Practice PDF Author: Richard D. Urman
Publisher: Cambridge University Press
ISBN: 1107400457
Category : Medical
Languages : en
Pages : 343

Book Description
A concise, practical handbook giving up-to-date, evidence based, 'how to' guidance on safe, effective procedural sedation.

Pharmacology of Pain

Pharmacology of Pain PDF Author: Pierre Beaulieu
Publisher: Lippincott Williams & Wilkins
ISBN: 1496331915
Category : Medical
Languages : en
Pages : 978

Book Description
Pharmacology of Pain provides a complete review of the pharmacology of pain, including mechanisms of drug actions, clinical aspects of drug usage, and new developments. This authoritative book describes the different systems involved in the perception, transmission, and modulation of pain and discusses the available options for pharmacological treatment of pain. Who should buy this book? Pharmacology of Pain is a particularly useful resource for: Basic researchers and clinicians, including physicians, dentists, pharmacists, nurses, and physical therapists Other professionals in the field of pain research and treatment Students and trainees

Academic Pain Medicine

Academic Pain Medicine PDF Author: Yury Khelemsky
Publisher: Springer
ISBN: 3030180050
Category : Medical
Languages : en
Pages : 386

Book Description
This comprehensive text is the definitive academic pain medicine resource for medical students, residents and fellows. Acting as both an introduction and continued reference for various levels of training, this guide provides practitioners with up-to-date academic standards. In order to comprehensively meet the need for such a contemporary text—treatment options, types of pain management, and variables affecting specific conditions are thoroughly examined across 48 chapters. Categories of pain conditions include orofacial, neuropathic, visceral, neck, acute, muscle and myofascial, chronic urogenital and pelvic, acute, and regional. Written by renowned experts in the field, each chapter is supplemented with high-quality color figures, tables and images that provide the reader with a fully immersive educational experience. Academic Pain Medicine: A Practical Guide to Rotations, Fellowship, and Beyond is an unprecedented contribution to the literature that addresses the wide-spread requisite for a practical guide to pain medicine within the academic environment.

Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry PDF Author: Annette M. Doherty
Publisher: Academic Press
ISBN: 9780120405381
Category : Medical
Languages : en
Pages : 484

Book Description
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expected to provide the basis for entirely new future therapies. Sections I-IV are disease-orientated and generally report on specific medicinal agents. Sections V-VI continue to emphasize important topics in medicinal chemistry, biology and drug design. In addition to the chapter reviews, a comprehensive set of indices has been included to enable the reader to easily locate topics in Volumes 1-38 of this series.

Acute Pain Management

Acute Pain Management PDF Author: Raymond S. Sinatra
Publisher: Cambridge University Press
ISBN: 0521874912
Category : Medical
Languages : en
Pages : 729

Book Description
This textbook provides an overview of pain management useful to specialists as well as non-specialists, surgeons, and nursing staff.