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Author: Adrian Dalca Publisher: Academic Press ISBN: 9780128139684 Category : Technology & Engineering Languages : en Pages : 0
Book Description
Imaging Genetics presents the latest research in imaging genetics methodology for discovering new associations between imaging and genetic variables, providing an overview of the state-of the-art in the field. Edited and written by leading researchers, this book is a beneficial reference for students and researchers, both new and experienced, in this growing area. The field of imaging genetics studies the relationships between DNA variation and measurements derived from anatomical or functional imaging data, often in the context of a disorder. While traditional genetic analyses rely on classical phenotypes like clinical symptoms, imaging genetics can offer richer insights into underlying, complex biological mechanisms.
Author: Adrian Dalca Publisher: Academic Press ISBN: 9780128139684 Category : Technology & Engineering Languages : en Pages : 0
Book Description
Imaging Genetics presents the latest research in imaging genetics methodology for discovering new associations between imaging and genetic variables, providing an overview of the state-of the-art in the field. Edited and written by leading researchers, this book is a beneficial reference for students and researchers, both new and experienced, in this growing area. The field of imaging genetics studies the relationships between DNA variation and measurements derived from anatomical or functional imaging data, often in the context of a disorder. While traditional genetic analyses rely on classical phenotypes like clinical symptoms, imaging genetics can offer richer insights into underlying, complex biological mechanisms.
Author: Kristin L. Bigos Publisher: Oxford University Press ISBN: 0190209771 Category : Medical Languages : en Pages : 433
Book Description
The field of neuroimaging genetics has grown exponentially over the past decade. To date there are more than 10,000 published papers involving MRI, PET, MEG and genetics. Neuroimaging Genetics: Principles and Practices is the comprehensive volume edited by Drs. Bigos, Hariri, and Weinberger and co-authored by the preeminent scholars in the field. This text reviews the basic principles of neuroimaging techniques and their application to neuroimaging genetics. The work presented in this volume elaborates on the explosive interest from diverse research areas in psychiatry and neurology in the use of imaging genetics as a unique tool to establish and identify mechanisms of risk, establish biological significance, and extend statistical evidence of genetic associations. Examples throughout highlight the application of imaging genetics to understand neurochemical systems and pathways, explore relationships between genetics and the structural and functional connectivity in human brain, and provide insight into mechanisms of risk for psychiatric and neurologic illness.
Author: Stephen Strakowski Publisher: Oxford University Press ISBN: 0197574521 Category : Manic-depressive illness Languages : en Pages : 329
Book Description
"Although efforts to examine the structure and function of the human brain stretch back centuries (Paluzzi et al, 2007), techniques allowing the study of living humans are a relatively recent development. Early investigators confined themselves to largely studying external features, with 18th century methodologies such as phrenology purporting to link extracranial proxies for brain size and structure to specific personality traits (Livianos-Aldana et al, 2007). However, these techniques did not prove useful for either clinical or research purposes. Two-dimensional x-ray imaging, while constituting an important medical advance, did not provide sufficient soft tissue contrast to be useful for studying "functional" psychiatric disorders such as bipolar disorder; techniques to enhance contrast, such as ventriculography and pneumoencephalography were similarly limited (Figure 1.1). Wide-spread in vivo studies of brain morphometry had to await the development of computed tomography imaging (CT) in the early 1970s. By the early 1980s CT was already being applied to the study of bipolar disorder (Pearlson et al, 1981)"--
Author: Marek Kubicki Publisher: Springer Nature ISBN: 3030352064 Category : Medical Languages : en Pages : 432
Book Description
This comprehensive book explains the importance of imaging techniques in exploring and understanding the role of brain abnormalities in schizophrenia. The findings obtained using individual imaging modalities and their biological interpretation are reviewed in detail, and updates are provided on methodology, testable hypotheses, limitations, and new directions for research. The coverage also includes important recent applications of neuroimaging to schizophrenia, for example in relation to non-pharmacological interventions, brain development, genetics, and prediction of treatment response and outcome. Written by world renowned experts in the field, the book will be invaluable to all who wish to learn about the newest and most important developments in neuroimaging research in schizophrenia, how these developments relate to the last 30 years of research, and how they can be leveraged to bring us closer to a cure for this devastating disorder. Neuroimaging in Schizophrenia will assist clinicians in navigating what is an extremely complex field and will be a source of insight and stimulation for researchers.
Author: Henry Kennedy Publisher: Springer ISBN: 3319277774 Category : Medical Languages : en Pages : 173
Book Description
This book has brought together leading investigators who work in the new arena of brain connectomics. This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron, axon, dendrite, synapse, and glial process within restricted brain regions; and ‘meso-connectome’ efforts to systematically map both local and long-distance connections using anatomical tracers. This book highlights cutting-edge methods that can accelerate progress in elucidating static ‘hard-wired’ circuits of the brain as well as dynamic interactions that are vital for brain function. The power of connectomic approaches in characterizing abnormal circuits in the many brain disorders that afflict humankind is considered. Experts in computational neuroscience and network theory provide perspectives needed for synthesizing across different scales in space and time. Altogether, this book provides an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Author: Bryon Adinoff Publisher: John Wiley & Sons ISBN: 1119972701 Category : Medical Languages : en Pages : 539
Book Description
Neuroimaging in Addiction presents an up-to-date, comprehensive review of the functional and structural imaging human studies that have greatly advanced our understanding of this complex disorder. Approaching addiction from a conceptual rather than a substance-specific perspective, this book integrates broad neuropsychological constructs that consider addiction as a neuroplastic process with genetic, developmental, and substance-induced contributions. The internationally recognized contributors to this volume are leaders in clinical imaging with expertise that spans the addiction spectrum. Following a general introduction, an overview of neural circuitry and modern non-invasive imaging techniques provides the framework for subsequent chapters on reward salience, craving, stress, impulsivity and cognition. Additional topics include the use of neuroimaging for the assessment of acute drug effects, drug-induced neurotoxicity, non-substance addictive behaviors, and the application of imaging genetics to identify unique intermediate phenotypes. The book concludes with an exploration of the future promise for functional imaging as guide to the diagnosis and treatment of addictive disorders. Scientists and clinicians will find the material in this volume invaluable in their work towards understanding the addicted brain, with the overall goal of improved prevention and treatment outcomes for patients. Features a Foreword by Edythe London, Director of the Center for Addictive Behaviors, University of California at Los Angeles.
Author: John R Absher Publisher: Academic Press ISBN: 0128011661 Category : Medical Languages : en Pages : 422
Book Description
Neuroimaging Personality, Social Cognition, and Character covers the science of combining brain imaging with other analytical techniques for use in understanding cognition, behavior, consciousness, memory, language, visual perception, emotional control, and other human attributes. Multidimensional brain imaging research has led to a greater understanding of character traits such as honesty, generosity, truthfulness, and foresight previously unachieved by quantitative mapping. This book summarizes the latest brain imaging research pertaining to character with structural and functional human brain imaging in both normal individuals and those with brain disease or disorder, including psychiatric disorders.By reviewing and synthesizing the latest structural and functional brain imaging research related to character, this book situates itself into the larger framework of cognitive neuroscience, psychiatric neuroimaging, related fields of research, and a wide range of academic fields, such as politics, psychology, medicine, education, law, and religion. - Provides a novel innovative reference on the emerging use of neuroimaging to reveal the biological substrates of character, such as optimism, honesty, generosity, and others - Features chapters from leading physicians and researchers in the field - Contains full-color text that includes both an overview of multiple disciplines and a detailed review of modern neuroimaging tools as they are applied to study human character - Presents an integrative volume with far-reaching implications for guiding future imaging research in the social, psychological and medical sciences, and for applying these findings to a wide range of non-clinical disciplines such as law, politics, and religion - Connects brain structure and function to human character and integrates modern neuroimaging techniques and other research methods for this purpose
Author: Cynthia H. Y. Fu Publisher: CRC Press ISBN: 9781841842295 Category : Medical Languages : en Pages : 288
Book Description
New neuroimaging techniques are developing at a break neck pace-every academic journal contains glossy pictures of brain activity corresponding to a particular task emblazoned in glorious technicolor. Discoveries about brain function in psychiatric disorders have been made at an equally rapid rate. However, most books on the subject have been written from a technical point of view. An introductory, easy-to-read guide, Neuroimaging in Psychiatry provides an overview and the clinical relevance of the latest neuroimaging findings. With contributions from an international panel of experts, this book reviews current findings from neuroimaging in schizophrenia, obsessive-compulsive disorder, depression, eating disorders, psychopathy, aging, and drug addiction. Chapter authors explore innovative and imaginative uses of neuro imaging technology, implications for our understanding of these disorders, and their impact on clinical practice. The book gives you a general overview of the main techniques to help you successfully complete a neuroimaging project.
Author: Kamil Uludag Publisher: Springer ISBN: 1489975918 Category : Medical Languages : en Pages : 926
Book Description
This volume explores the revolutionary fMRI field from basic principles to state-of-the-art research. It covers a broad spectrum of topics, including the history of fMRI's development using endogenous MR blood contrast, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visual system, auditory cortex, and sensorimotor system; genetic imaging using fMRI, multimodal neuroimaging, brain bioenergetics and function and molecular-level fMRI. Comprehensive and intuitively structured, this book engages the reader with a first-person account of the development and history of the fMRI field by the authors. The subsequent sections examine the physiological basis of fMRI, the basic principles of fMRI and its applications and the latest advances of the technology, ending with a discussion of fMRI’s future. fMRI: From Nuclear Spins to Brain Function, co-edited by leading and renowned fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is an ideal resource for clinicians and researchers in the fields of neuroscience, psychology and MRI physics.
Author: Adrian Dalca
Author: Adrian Dalca
Author: Kristin L. Bigos
Author: Stephen Strakowski
Author: Marek Kubicki
Author: Virginia Ng
Author: Henry Kennedy
Author: Bryon Adinoff
Author: John R Absher
Author: Cynthia H. Y. Fu
Author: Kamil Uludag