Neural Plasticity and Disorders of the Nervous System PDF Download

Author: Aage R. Møller
Publisher: Cambridge University Press
ISBN: 1139447998
Category : Medical
Languages : en
Pages : 380

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Book Description
Neural Plasticity and Disorders of the Nervous System provides comprehensive coverage of the pathophysiology of neurological disorders emphasising those disorders where expression of plasticity is evident. Including the basis for the expression of neural plasticity; how reorganisation of the nervous system can cause hyperactivity in sensory systems producing central neuropathic pain, tinnitus and paresthesia; the role of little-known non-classical pathways in pain and sensory disorders and their subcortical connections; hyper- and hypoactivity of motor systems after injury, and the role of spinal reflexes and internal processing in the spinal cord. Phantom symptoms and disorders of nerves and associated disorders are discussed, along with disorders that can be cured by microvascular decompression operations. A detailed and comprehensive description of the organisation of pain circuits and sensory and motor nervous systems is also included. This 2006 text is aimed at students and graduates of neuroscience and medicine.

Author: Aage R. Mlløer
Publisher:
ISBN: 9780511140327
Category : Nervous system
Languages : en
Pages : 394

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Book Description
The book describes how the expression of neural plasticity can go wrong and cause symptoms of disorders and diseases instead of being beneficial. Relevant anatomy and physiology of the nervous system and how such changes in the organization of the nervous system may be reversed are also discussed.

Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1466584920
Category : Medical
Languages : en
Pages : 424

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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

Author: Sarah H. Broman
Publisher: Oxford University Press
ISBN: 0198028458
Category : Medical
Languages : en
Pages : 430

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Book Description
This book provides an integrated review of current research on neural plasticity and reorganization after early cerebral insults. Addressing both animal studies and a variety of diverse clinical populations, including children with congenital brain malformations, focal lesions, autism, and pervasive developmental disorders, this book summarizes many of the major advances on neural plasticity made in these areas over the past several years. Characterized by a broad historical perspective including contributions from some of the earliest researchers on environmental factors and brain organization, the book advances the reader form the laboratory to application in several human populations. Many of the components of the book explicitly address relationships of animal and human models, showing that the laboratory and the clinic are overlapping settings, not isolated chambers as they are often perceived. The understanding of neural plasticity and both biological and environmental factors that influence brain reorganization after early cerebral insult has major implications for treatment. The book outlines many of the potential applications for treatment of early brain disorders. The contributors include basic neuroscientists, cognitive neuroscientists, and clinician-researchers who work together to bridge gaps among disciplines. The book should facilitate collaborative research and applications in the critical areas of neural plasticity and brain reorganization. Advancement of knowledge of factors that prevent and enhance brain reorganization after early cerebral insult is a key to unraveling the mysteries of the developmental disorders characteristic of children and which influence their development through adulthood.

Author: Joseph I. Tracy
Publisher: Oxford University Press, USA
ISBN: 0199965242
Category : Medical
Languages : en
Pages : 433

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Book Description
This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Author: James L. McGaugh
Publisher: Routledge
ISBN: 1317729013
Category : Psychology
Languages : en
Pages : 220

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Book Description
Catalyzed by the development of new neurobiological and behavioral techniques as well as new conceptual and theoretical approaches to the study of the relationship between brain and behavior, research exploring brain functions enabling learning and memory has greatly accelerated in recent years. The chapters in this book reflect current theoretical approaches to the study of brain and memory and provide new insights concerning the cellular bases of memory and the differential involvement of brain systems in different forms of memory. By presenting up-to-date summaries of research investigating brain mechanisms underlying learning and memory, these chapters help to place current findings in appropriate theoretical context, and further stimulate research inquiry attempting to understand how the brain makes memory. Divided into three sections, coverage in this volume includes: * a discussion of pharmacological approaches to the study of brain and memory; * a review of experiments using a variety of techniques, including brain lesions, brain grafting, and electrophysiological recording to investigate the role of different brain regions in learning and memory; and * an examination of molecular analyses of events associated with memory formation.

Author: P. Herrling
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805582986
Category : Medical
Languages : en
Pages : 70

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Book Description
This special topic issue of 'Neurodegenerative Diseases' contains contributions discussing the subject in-depth. 'Neurodegenerative Diseases' is a well-respected, international peer-reviewed journal in Neurobiology. Special topic issues are included in the subscription.

Author: Hans Flohr
Publisher: Springer Science & Business Media
ISBN: 3642738494
Category : Medical
Languages : en
Pages : 692

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Book Description
Neural networks are not rigidly wired but rather highly plastic structures, the functional architecture of which can be actively reorganized in response to external or internal events. Lesions of such networks induce plastic processes which in time may lead to a recovery of the initially disrupted function. This type of neural plasticity is the main focus of the book, which presents a broad spectrum of experimental paradigms for lesion-induced plasticity as in the spinal cord, the vestibular, oculomotor, visual and olfactory system, the cerebellum and the cerebral cortex, including recent methodological developments. Concepts and perspectives in understanding neural plasticity are reported in reviews and original research reports and are thoroughly discussed.

Author: Charles E. Ribak
Publisher: Oxford University Press
ISBN: 0195369009
Category : Medical
Languages : en
Pages : 404

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Book Description
This book provides current information about the three areas mentioned in the title: Neuronal Migration and Development, Degenerative Brain Diseases, and Neural Plasticity and Regeneration. The chapters about brain development examine the cellular and molecular mechanisms by which neurons are generated from the ventricular zone in the forebrain and migrate to their destinations in the cerebral cortext. This description of cortical development also includes a discussions of the Cajal-Retzius cell. Another chapter provides insight about the development of another forebrain region, the hypothalamus. The remaining chapters of this section examine the clinical relevance of brain development in certain disease states in humans: neural tube defects and the normal and abnormal development of human electroencephalographic recordings during the first year of age.The second section on degenerative disorders of the brain begins wtih details about the dopaminergic neurons in the substantia niger and their loss in Parkinson's disease. Two subsequent chapters describe changes in brain aging, including changes in the numbers of myelinated axons. Other chapters in this section describe important cellular and molecular changes found in Alzheimer's disease and human epilepsy. Together, these chapters summarize much of our current knowledge about the major molecular and cellular changes found in several degenerative diseases of the brain.The last section addresses the issues of brain plasticity and regeneration in the adult brain and begins with a chapter on how the brain's own stem cells provide newly generated neurons to the hippocampal dentate gyrus and how these neurons become integrated into neural circuitry. The following two chapters examine some of the neuroplastic changes that take place in motor and sensory cortices of awake behaving primates. The concluding two chapters address the issue of regeneration in the injured spinal cord and the factors that may contribute to its success.

Author: C.L. Cazzullo
Publisher: Springer Science & Business Media
ISBN: 9400908512
Category : Medical
Languages : en
Pages : 247

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Book Description
In the last few years ways of thinking in psychiatry have undergone considerable change thanks to advances in the fields of morphology and plasticity of the CNS, particularly with regard to schizophrenic and mood disorders. In addition, the rapid and considerable development of neuroimaging techniques (CT, MRI, PET and computerized EEG) and of molecular genetics (through DNA recombinant meth odologies) have widened the approach to these disorders in a way unimagined a few years ago. These advances and the new etiopathogenetic hypotheses that have sprung from them were the central theme of the Second International Meeting on Schizophre nia "Morphology and Plasticity of the Central Nervous System - A Challenge for Psychiatry of the Nineties" which was organized by the Association for Research on Schizophrenia (ARS), the Schizophrenia Research Center of the Institute of Psychiatry of the University of Milan and the T. and F. Legrenzi Foundation, held in Milan on October 22-24, 1987. This book contains the contributions from participants of the meeting, which took place in a warm and friendly atmosphere and marked by lively and exhaustive discussions on the various papers. The contributions were recently revised for the present publication. We would like to express our appreciation to the book's contributors for the high quality of their reports.