Natural Small Molecule Drugs from Plants PDF Download

Author: Guan-Hua Du
Publisher: Springer
ISBN: 9811080224
Category : Medical
Languages : en
Pages : 702

View

Book Description
This book discusses 120 types of natural, small-molecule drugs derived from plants. They are grouped into 7 parts according their clinical uses, such as drugs for cardiovascular diseases, for metabolic diseases, for neuropsychiatric diseases, for immune-mediated inflammatory diseases, anti-tumor drugs, and drugs for parasites and bacterial infection. Each chapter systematically summarizes one drug, including its physicochemical properties, sources, pharmacological effects and clinical applications. To help readers understand the drug better, the research and pharmacological activity for each drug is also described, which serves as a salutary lesson for future drug development. Written by frontline researchers, teachers and clinicians working in field of pharmacy and pharmacology it provides an overview of natural, small-molecule drugs derived from plants for researchers in the field.

Author: Iris F. F. Benzie
Publisher: CRC Press
ISBN: 1439807167
Category : Health & Fitness
Languages : en
Pages : 500

View

Book Description
The global popularity of herbal supplements and the promise they hold in treating various disease states has caused an unprecedented interest in understanding the molecular basis of the biological activity of traditional remedies. Herbal Medicine: Biomolecular and Clinical Aspects focuses on presenting current scientific evidence of biomolecular ef

Author: National Academy of Sciences/Smithsonian Institution
Publisher: National Academies Press
ISBN: 0309037395
Category : Science
Languages : en
Pages : 535

View

Book Description
This important book for scientists and nonscientists alike calls attention to a most urgent global problem: the rapidly accelerating loss of plant and animal species to increasing human population pressure and the demands of economic development. Based on a major conference sponsored by the National Academy of Sciences and the Smithsonian Institution, Biodiversity creates a systematic framework for analyzing the problem and searching for possible solutions.

Author: Andrew Pengelly
Publisher: Routledge
ISBN: 1000247937
Category : Body, Mind & Spirit
Languages : en
Pages : 168

View

Book Description
Pengelly's user friendly text will encourage educators in medical science to consider using this material in the complementary medicine/nutraceuticals areas May I congratulate Andrew Pengelly for writing this text as it is going to be very popular with undergraduate students as well as more experienced readers.' D. Green, London Metropolitan University, UK This unique book explains in simple terms the commonly occurring chemical constituents of medicinal plants. The major classes of plant constituents such as phenols, terpenes and polysaccharides, are described both in terms of their chemical structures and their pharmacological activities. Identifying specific chemical compounds provides insights into traditional and clinical use of these herbs, as well as potential for adverse reactions. Features include: * Over 100 diagrams of chemical structures * References to original research studies and clinical trials * References to plants commonly used throughout Europe, North America and Australasia. Written by an experienced herbal practitioner, The Constituents of Medicinal Plants seriously challenges any suggestion that herbal medicine remains untested and unproven, including as it does hundreds of references to original research studies and trials. Designed as an undergraduate text, the first edition of this book became an essential desktop reference for health practitioners, lecturers, researchers, producers and anyone with an interest in how medicinal herbs work. This edition has been extensively revised to incorporate up-to-date research and additional sections, including an expanded introduction to plant molecular structures, and is destined to become a classic in the literature of herbal medicine.

Author: H.K. Wagner
Publisher: Springer Science & Business Media
ISBN: 3642666825
Category : Medical
Languages : en
Pages : 299

View

Book Description
The fact that, of the approximately 600,000 plant species existing on the earth, only some 5 % have been specifically investigated chemically or pharmacologi cally, is a challenge to chemists spezializing in na tural substances and to pharmacologists. In view of the limited number of research capacities and the ever diminishing financial means, this challenge can only be met if, together with an improvement and refinement of methods of analysis, medicinal plant research is carried out on a broader interdisciplinary basis, with comparable, scientifically recognized screening methods, and if it is better coordinated, with greater use of modern documentation means. It is thus necessary in the future to concentrate specifically on projects leading to the development of new medicinal prepara tions. The plenary lectures hold in the present symposium of the 1st International Congress for Research on Medi cinal Plants reflect these efforts and tendencies. At the same time they provide a survey of some of the fields of medicinal plant research which are at present most actual and most intensively researched. They range from plant screening, isolation and structure eluci dation of new principles, to the therapeutical opti mization of a natural product. The lectures given at this congress show clearly the necessity, in addition to national phytochemical so cieties, for a central international organisation, in which all active medicinal plant researchers in the world are included. Their aim should be to provide the impulse for more optimal, rational research, aimed at the solution of specific projects.

Author: George E. Barreto
Publisher: Springer Nature
ISBN: 3030648729
Category : Medical
Languages : en
Pages : 603

View

Book Description
Medicinal plants and their derived products remain as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery. There are several advantages for plant-derived therapeutics including wide availability, diverse pharmacological actions and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying to the efficacy and safety of medicinal plants and phytochemicals in ameliorating several human diseases. A plethora of basic studies has also unravelled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products and drug interactions remain to be further studied. In this book, we aim to put together several chapters on the medicinal properties and pharmacological action of medicinal plants, plant species and phytochemicals. The goal is to present a comprehensive collection on most of the therapeutic aspects of plant-derived natural products and molecular mechanisms thereof.

Author: Ashish Tewari
Publisher: Elsevier
ISBN: 0081022743
Category : Science
Languages : en
Pages : 384

View

Book Description
Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design - Includes detailed coverage of therapeutic compound synthesis - Uses multiple real-world examples to support content - Lays out a sustainable template for the future of developing active agents from natural products

Author: Anne E. Osbourn
Publisher: Springer Science & Business Media
ISBN: 0387854983
Category : Science
Languages : en
Pages : 588

View

Book Description
Plants produce a huge array of natural products (secondary metabolites). These compounds have important ecological functions, providing protection against attack by herbivores and microbes and serving as attractants for pollinators and seed-dispersing agents. They may also contribute to competition and invasiveness by suppressing the growth of neighboring plant species (a phenomenon known as allelopathy). Humans exploit natural products as sources of drugs, flavoring agents, fragrances and for a wide range of other applications. Rapid progress has been made in recent years in understanding natural product synthesis, regulation and function and the evolution of metabolic diversity. It is timely to bring this information together with contemporary advances in chemistry, plant biology, ecology, agronomy and human health to provide a comprehensive guide to plant-derived natural products. Plant-derived natural products: synthesis, function and application provides an informative and accessible overview of the different facets of the field, ranging from an introduction to the different classes of natural products through developments in natural product chemistry and biology to ecological interactions and the significance of plant-derived natural products for humans. In the final section of the book a series of chapters on new trends covers metabolic engineering, genome-wide approaches, the metabolic consequences of genetic modification, developments in traditional medicines and nutraceuticals, natural products as leads for drug discovery and novel non-food crops.

Author: Namrita Lall
Publisher: Academic Press
ISBN: 0128124768
Category : Technology & Engineering
Languages : en
Pages : 330

View

Book Description
Medicinal Plants for Holistic Health and Well-Being discusses, in depth, the use of South African plants to treat a variety of ailments, including tuberculosis, cancer, periodontal diseases, acne, postmacular hypomelanosis, and more. Plants were selected on the basis of their traditional use, and the book details the scientific evidence that supports their pharmacological and therapeutic potential to safely and effectively treat each disease. Thus, this book is a valuable resource for all researchers, students and professors involved in advancing global medicinal plant research. Many plants found in South Africa are also found in other parts of the world. Each chapter highlights plants from other worldwide locations so that scientists can study which plants belong to the same family, and how similar qualities can be used to treat a specific disease. - The book details the scientific evidence that supports their pharmacological and therapeutic potential to safely and effectively treat each disease - Each chapter highlights plants from worldwide locations so that scientists can study plants belonging to the same family, and how similar species can be used to treat a specific disease - Use of traditional medicine as an efficient means to identify and further investigate South African, similar plants and plant-derived compounds in modern drug discovery - Includes a number of chapters dedicated to using medicinal plants to treat various skin disorders, which is often not covered in other books on medicinal plants - Organized by specific diseases, with vital evidence-based data related to the bioactivity, pharmacological potential, chemical structure and safety information

Author: Judith Sumner
Publisher: Timber Press
ISBN: 9780881929577
Category : Science
Languages : en
Pages : 0

View

Book Description
Wild and cultivated plants have provided humans with cures for thousands of years. Aspirin, for example, the most widely used drug in the Western pharmacopoeia, was first isolated from willows to treat fever, pain, and inflammation. Writing for the lay reader, the author surveys the history of the use of plants in medicine, the range of chemicals produced by plants, and the prospects for future discoveries. This book is only available through print on demand. All interior art is black and white.