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Author: Sandra Knowles Weller Publisher: Caister Academic Press Limited ISBN: 9781904455769 Category : Science Languages : en Pages : 0
Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
Author: Sandra Knowles Weller Publisher: Caister Academic Press Limited ISBN: 9781904455769 Category : Science Languages : en Pages : 0
Book Description
Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
Author: Sampson Ejike Odum Publisher: iUniverse ISBN: 1663205043 Category : Fiction Languages : en Pages : 123
Book Description
‘KUMBA AFRICA’, is a compilation of African Short Stories written as fiction by Sampson Ejike Odum, nostalgically taking our memory back several thousands of years ago in Africa, reminding us about our past heritage. It digs deep into the traditional life style of the Africans of old, their beliefs, their leadership, their courage, their culture, their wars, their defeat and their victories long before the emergence of the white man on the soil of Africa. As a talented writer of rich resource and superior creativity, armed with in-depth knowledge of different cultures and traditions in Africa, the Author throws light on the rich cultural heritage of the people of Africa when civilization was yet unknown to the people. The book reminds the readers that the Africans of old kept their pride and still enjoyed their own lives. They celebrated victories when wars were won, enjoyed their New yam festivals and villages engaged themselves in seasonal wrestling contest etc; Early morning during harmattan season, they gathered firewood and made fire inside their small huts to hit up their bodies from the chilling cold of the harmattan. That was the Africa of old we will always remember. In Africa today, the story have changed. The people now enjoy civilized cultures made possible by the influence of the white man through his scientific and technological process. Yet there are some uncivilized places in Africa whose people haven’t tested or felt the impact of civilization. These people still maintain their ancient traditions and culture. In everything, we believe that days when people paraded barefooted in Africa to the swarmp to tap palm wine and fetch firewood from there farms are almost fading away. The huts are now gradually been replaced with houses built of blocks and beautiful roofs. Thanks to modern civilization. Donkeys and camels are no longer used for carrying heavy loads for merchants. They are now been replaced by heavy trucks and lorries. African traditional methods of healing are now been substituted by hospitals. In all these, I will always love and remember Africa, the home of my birth and must respect her cultures and traditions as an AFRICAN AUTHOR.
Author: Renee Davenport Publisher: ISBN: 9780997744774 Category : Crafts & Hobbies Languages : en Pages : 74
Book Description
Sweet Girls ~ Beautiful Women Retro ~ Vintage Adult Grayscale Coloring Book.This book can be colored by women, men, teens, and some children. Thirty-one sweet girls and beautiful women portraits for you to color.Color over all of the varying shades of gray to make your portrait come to life. Use different colors to highlight, shade, and shadow coloring pages. Colored pencils, gel pens, glitter pens, Prismacolors, Raffine Marco pencils, and Marco Renoir pencils are among the most popular. The backgrounds are made for you to either color or leave them as they are. It's the colorist's choice. This grayscale coloring book includes- 1. 31 high-quality grayscale coloring pages. 2. 8.5" x 11" pages. 3. Each page is one sided. 4. Each page has a large portrait of either a sweet girl or a lovely woman. 5. Different elements are on the pages for you to color. Feel free to review the coloring book and let me know how you enjoyed your coloring. Please visit JoyfulColoringBooks.com and join my newsletter. If you have a picture of a special pet or something else you would like made into grayscale coloring pages please contact me. I'll be happy to make a custom grayscale coloring page or coloring book for you. Please contact me at [email protected] More books to come! Enjoy your coloring journey! See the flip-through of the coloring pages here”youtube.com/channel/UCroL0Govs-YVWAJlOhm4_XA/videos
Author: Sandra Knowles Weller
Author: Sandra Knowles Weller
Author: Rigby
Author: Bill Staines
Author: 
Author: Sampson Ejike Odum
Author: Neal Walters
Author: 
Author: Renee Davenport