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Author: Jurriaan Huskens Publisher: John Wiley & Sons ISBN: 1119143462 Category : Science Languages : en Pages : 434
Book Description
Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.
Author: Jurriaan Huskens Publisher: John Wiley & Sons ISBN: 1119143462 Category : Science Languages : en Pages : 434
Book Description
Connects fundamental knowledge of multivalent interactions with current practice and state-of-the-art applications Multivalency is a widespread phenomenon, with applications spanning supramolecular chemistry, materials chemistry, pharmaceutical chemistry and biochemistry. This advanced textbook provides students and junior scientists with an excellent introduction to the fundamentals of multivalent interactions, whilst expanding the knowledge of experienced researchers in the field. Multivalency: Concepts, Research & Applications is divided into three parts. Part one provides background knowledge on various aspects of multivalency and cooperativity and presents practical methods for their study. Fundamental aspects such as thermodynamics, kinetics and the principle of effective molarity are described, and characterisation methods, experimental methodologies and data treatment methods are also discussed. Parts two and three provide an overview of current systems in which multivalency plays an important role in chemistry and biology, with a focus on the design rules, underlying chemistry and the fundamental principles of multivalency. The systems covered range from chemical/materials-based ones such as dendrimers and sensors, to biological systems including cell recognition and protein binding. Examples and case studies from biochemistry/bioorganic chemistry as well as synthetic systems feature throughout the book. Introduces students and young scientists to the field of multivalent interactions and assists experienced researchers utilising the methodologies in their work Features examples and case studies from biochemistry/bioorganic chemistry, as well as synthetic systems throughout the book Edited by leading experts in the field with contributions from established scientists Multivalency: Concepts, Research & Applications is recommended for graduate students and junior scientists in supramolecular chemistry and related fields, looking for an introduction to multivalent interactions. It is also highly useful to experienced academics and scientists in industry working on research relating to multivalent and cooperative systems in supramolecular chemistry, organic chemistry, pharmaceutical chemistry, chemical biology, biochemistry, materials science and nanotechnology.
Author: Bertram O. Fraser-Reid Publisher: Springer Science & Business Media ISBN: 3540361545 Category : Science Languages : en Pages : 2847
Book Description
As a reflection of the quantum leap that has been made in the study of glycostructures, the first edition of this book has been completely revised and updated. The editors give up-to-date information on glycostructures, their chemistry and chemical biology in the form of a completely comprehensive survey. Glycostructures play highly diverse and crucial roles in a myriad of organisms and important systems in biology, physiology, medicine, bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and the chemistry behind them. While many facts remain undiscovered, this MRW has been contributed to by a large number of the world’s leading researchers in the field.
Author: Binghe Wang Publisher: John Wiley & Sons ISBN: 0470592079 Category : Medical Languages : en Pages : 448
Book Description
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition.
Author: Ajit Varki Publisher: CSHL Press ISBN: 9780879696818 Category : Medical Languages : en Pages : 694
Book Description
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author: Eleanor Betts Publisher: Taylor & Francis ISBN: 1317057287 Category : History Languages : en Pages : 248
Book Description
The Roman empire afforded a kaleidoscope of sensations. Through a series of multisensory case studies centred on people, places, buildings and artefacts, and on specific aspects of human behaviour, this volume develops ground-breaking methods and approaches for sensory studies in Roman archaeology and ancient history. Authors explore questions such as: what it felt like, and symbolised, to be showered with saffron at the amphitheatre; why the shape of a dancer’s body made him immediately recognisable as a social outcast; how the dramatic gestures, loud noises and unforgettable smells of a funeral would have different meanings for members of the family and for bystanders; and why feeling the weight of a signet ring on his finger contributed to a man’s sense of identity. A multisensory approach is taken throughout, with each chapter exploring at least two of the senses of sight, hearing, smell, taste and touch. The contributors’ individual approaches vary, reflecting the possibilities and the wide application of sensory studies to the ancient world. Underlying all chapters is a conviction that taking a multisensory approach enriches our understanding of the Roman empire, but also an awareness of the methodological problems encountered when reconstructing past experiences.
Author: Rebecca Langlands Publisher: Cambridge University Press ISBN: 1107040604 Category : Education Languages : en Pages : 381
Book Description
"The well-known mythographer Marina Warner has described the process of reading fairy tales and folktales as 'tasting the dragon's blood' - a magical and transformative process by which one's ears are opened to the voices of the past and of other worlds. Roman exempla, which constitute a national story-telling tradition, are very different in many ways from the dream-like fantasies of fairy-tales and other narrative folk traditions that have been the subject of Warner's studies. In (supposedly) true stories from history, battle-hardened warriors, noble maidens and honourable sons of the soil face impossible dangers, take terrible decisions and sacrifice their lives, their limbs and even their own children for the sake of justice, discipline and the Roman community. Yet for the ancient Romans too, hearing the blood-soaked stories of their ancestral heroes was an intimate and potent experience, and this 'taste of the hero's blood' had an intoxicating effect similar to the blood of Warner's dragon: evoking other worlds, shaping understanding of their own world"--
Author: Wolfgang Jahnke Publisher: John Wiley & Sons ISBN: 3527608605 Category : Science Languages : en Pages : 391
Book Description
This first systematic summary of the impact of fragment-based approaches on the drug development process provides essential information that was previously unavailable. Adopting a practice-oriented approach, this represents a book by professionals for professionals, tailor-made for drug developers in the pharma and biotech sector who need to keep up-to-date on the latest technologies and strategies in pharmaceutical ligand design. The book is clearly divided into three sections on ligand design, spectroscopic techniques, and screening and drug discovery, backed by numerous case studies.
Author: Publisher: Academic Press ISBN: 0123751772 Category : Technology & Engineering Languages : en Pages : 307
Book Description
Many of the devices and systems used in modern industry are becoming progressively smaller and have reached the nanoscale domain. Nanofabrication aims at building nanoscale structures, which can act as components, devices, or systems, in large quantities at potentially low cost. Nanofabrication is vital to all nanotechnology fields, especially for the realization of nanotechnology that involves the traditional areas across engineering and science. - Includes chapters covering the most important Nanofabrication techniques, which aids comprehensive understanding of the latest manufacturing technologies encountered in the field of nano-level manufacturing which is essential for preparing for advanced study and application in nanofabrication techniques by enabling thorough understanding of the entire nanofabrication process as it applies to advanced electronic and related manufacturing technologies - Each chapter covers a nanofabrication technique comprehensively, which allows the reader to learn to produce nanometer-level products as well as collect, process, and analyze data, improve process parameters, and how to assist engineers in research, development and manufacture of the same - Includes contributions from recognized experts from around the globe, making the reader aware of variations in similar techniques applied in different geographical locations and is better positioned to establish all possible global applications
Author: Ilker Ozsahin Publisher: Academic Press ISBN: 0128240873 Category : Computers Languages : en Pages : 334
Book Description
Applications of Multi-Criteria Decision-Making Theories in Healthcare and Biomedical Engineering contains several practical applications on how decision-making theory could be used in solving problems relating to the selection of best alternatives. The book focuses on assisting decision-makers (government, organizations, companies, general public, etc.) in making the best and most appropriate decision when confronted with multiple alternatives. The purpose of the analytical MCDM techniques is to support decision makers under uncertainty and conflicting criteria while making logical decisions. The knowledge of the alternatives of the real-life problems, properties of their parameters, and the priority given to the parameters have a great effect on consequences in decision-making. In this book, the application of MCDM has been provided for the real-life problems in health and biomedical engineering issues. - Provides a comprehensive analysis and application multi-criteria decision-making methods - Presents detail information about MCDM and their usage - Covers state-of-the-art MCDM methods and offers applications of MCDM for health and biomedical engineering purposes
Author: Christoph A. Schalley Publisher: John Wiley & Sons ISBN: 3527644148 Category : Science Languages : en Pages : 849
Book Description
The second edition of "Analytical Methods in Supramolecular Chemistry" comes in two volumes and covers a broad range of modern methods and techniques now used for investigating supramolecular systems, e. g. NMR spectroscopy, mass spectrometry, extraction methods, crystallography, single molecule spectroscopy, electrochemisty, and many more. In this second edition, tutorial inserts have been introduced, making the book also suitable as supplementary reading for courses on supramolecular chemistry. All chapters have been revised and updated and four new chapters have been added. A must-have handbook for Organic and Analytical Chemists, Spectroscopists, Materials Scientists, and Ph.D. Students in Chemistry. From reviews of the first edition: "This timely book should have its place in laboratories dealing with supramolecular objects. It will be a source of reference for graduate students and more experienced researchers and could induce new ideas on the use of techniques other than those usually used in the laboratory." Journal of the American Chemical Society (2008) VOL. 130, NO. 1 doi: 10.1021/ja0769649 "The book as a whole or single chapters will stimulate the reader to widen his horizon in chemistry and will help him to have new ideas in his research." Anal Bioanal Chem (2007) 389:2039-2040 DOI: 10.1007/s00216-007-1677-1
Author: Jurriaan Huskens
Author: Jurriaan Huskens
Author: Bertram O. Fraser-Reid
Author: Binghe Wang
Author: Ajit Varki
Author: Eleanor Betts
Author: Rebecca Langlands
Author: Wolfgang Jahnke
Author: 
Author: Ilker Ozsahin
Author: Christoph A. Schalley