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Author: Mithun Diwakar Publisher: ISBN: 9781124867786 Category : Languages : en Pages : 170
Book Description
Beamformer adaptive spatial filters have been used extensively in the field of magnetoencephalography (MEG) as tools to reconstruct functional activation of the brain. Conventional single beamformer techniques suffer from distortion in the presence of coherent activation of the cortex or are difficult to use due to the need of a priori information. These qualities present a major disadvantage to analyzing human brain responses, as coordinated functional responses require a degree of synchronous activation in different parts of the active cortex. In this dissertation, a novel beamformer technique, the multi-core beamformer, is developed that is robust to source correlation and does not require the use of a priori information. This novel approach is tested in both simulated and real experiments, including auditory and median-nerve stimulation, which provide well-studied systems to gauge the effectiveness of our new technique. Simulations show that the multi-core beamformer can successfully determine source time-courses, source powers, and source locations while minimizing or eliminating the distortion present in other methods. Results from real-life experiments show that the multi-core beamformer produces physiologically meaningful solutions that agree with previous functional imaging and neurophysiology studies. The use of the multi-core beamformer is expected to greatly contribute to the analysis of MEG recordings and, in general, improve our understanding of functional brain activity.
Author: Mithun Diwakar Publisher: ISBN: 9781124867786 Category : Languages : en Pages : 170
Book Description
Beamformer adaptive spatial filters have been used extensively in the field of magnetoencephalography (MEG) as tools to reconstruct functional activation of the brain. Conventional single beamformer techniques suffer from distortion in the presence of coherent activation of the cortex or are difficult to use due to the need of a priori information. These qualities present a major disadvantage to analyzing human brain responses, as coordinated functional responses require a degree of synchronous activation in different parts of the active cortex. In this dissertation, a novel beamformer technique, the multi-core beamformer, is developed that is robust to source correlation and does not require the use of a priori information. This novel approach is tested in both simulated and real experiments, including auditory and median-nerve stimulation, which provide well-studied systems to gauge the effectiveness of our new technique. Simulations show that the multi-core beamformer can successfully determine source time-courses, source powers, and source locations while minimizing or eliminating the distortion present in other methods. Results from real-life experiments show that the multi-core beamformer produces physiologically meaningful solutions that agree with previous functional imaging and neurophysiology studies. The use of the multi-core beamformer is expected to greatly contribute to the analysis of MEG recordings and, in general, improve our understanding of functional brain activity.
Author: Andrew C. Papanicolaou Publisher: Oxford University Press ISBN: 0190621400 Category : Psychology Languages : en Pages : 417
Book Description
The Oxford Handbook of Functional Brain Imaging in Neuropsychology and Cognitive Neurosciences describes in a readily accessible manner the several functional neuroimaging methods and critically appraises their applications that today account for a large part of the contemporary cognitive neuroscience and neuropsychology literature. The complexity and the novelty of these methods often cloud appreciation of the methods' contributions and future promise. The Handbook begins with an overview of the basic concepts of functional brain imaging common to all methods, and proceeds with a description of each of them, namely magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI), positron emission tomography (PET), diffusion tensor imaging (DTI), and transcranial magnetic stimulation (TMS). Its second part covers the various research applications of functional neuroimaging on issues like the function of the default mode network; the possibility and the utility of imaging of consciousness; the search for mnemonic traces of concepts; human will and decision-making; motor cognition; language; the mechanisms of affective states and pain; the presurgical mapping of the brain; and others. As such, the volume reviews the methods and their contributions to current research and comments on the degree to which they have enhanced our understanding of the relation between neurophysiological activity and sensory, motor, and cognitive functions. Moreover, it carefully considers realistic contributions of functional neuroimaging to future endeavors in cognitive neuroscience, medicine, and neuropsychology.
Author: Selma Supek Publisher: Springer ISBN: 3642330452 Category : Technology & Engineering Languages : en Pages : 999
Book Description
Magnetoencephalography (MEG) is an invaluable functional brain imaging technique that provides direct, real-time monitoring of neuronal activity necessary for gaining insight into dynamic cortical networks. Our intentions with this book are to cover the richness and transdisciplinary nature of the MEG field, make it more accessible to newcomers and experienced researchers and to stimulate growth in the MEG area. The book presents a comprehensive overview of MEG basics and the latest developments in methodological, empirical and clinical research, directed toward master and doctoral students, as well as researchers. There are three levels of contributions: 1) tutorials on instrumentation, measurements, modeling, and experimental design; 2) topical reviews providing extensive coverage of relevant research topics; and 3) short contributions on open, challenging issues, future developments and novel applications. The topics range from neuromagnetic measurements, signal processing and source localization techniques to dynamic functional networks underlying perception and cognition in both health and disease. Topical reviews cover, among others: development on SQUID-based and novel sensors, multi-modal integration (low field MRI and MEG; EEG and fMRI), Bayesian approaches to multi-modal integration, direct neuronal imaging, novel noise reduction methods, source-space functional analysis, decoding of brain states, dynamic brain connectivity, sensory-motor integration, MEG studies on perception and cognition, thalamocortical oscillations, fetal and neonatal MEG, pediatric MEG studies, cognitive development, clinical applications of MEG in epilepsy, pre-surgical mapping, stroke, schizophrenia, stuttering, traumatic brain injury, post-traumatic stress disorder, depression, autism, aging and neurodegeneration, MEG applications in cognitive neuropharmacology and an overview of the major open-source analysis tools.
Author: Roland Lee Publisher: Elsevier Health Sciences ISBN: 0323709419 Category : Medical Languages : en Pages : 153
Book Description
This issue of Neuroimaging Clinics of North America focuses on Magnetoencephalography (MEG), and is edited by Drs. Roland Lee and Mingxiong Huang. Articles will include: MEG signal processing, forward modeling, MEG inverse source imaging, and Coherence analysis; Magnetoencephalography for pre-surgical functional mapping; Magnetoencephalography for mild TBI and PTSD; Magnetoencephalography for autism; Magnetoencephalography for schizophrenia; Magnetoencephalography for Alzheimer's disease; Pediatric Magnetoencephalography; The MEG Measurement Techniques; MEG and Language/Linguistics; MEG for Epilepsy; Integration of MEG results into the patient workup – Merging multiple modalities; and more!
Author: Riitta Hari Publisher: Oxford University Press ISBN: 0197542182 Category : Medical Languages : en Pages : 481
Book Description
"Neuronal communication in the brain is associated with minute electrical currents that give rise to both electrical potentials on the scalp (measurable by means of electroencephalography [EEG]) and magnetic fields outside the head (measurable by means of magnetoencephalography [MEG]). Both MEG and EEG are noninvasive neurophysiological methods used to study brain dynamics, temporal changes in the activation patterns, and sequences. Their differences between MEG and EEG mainly reflect differences in the spread of electric potentials and magnetic fields generated by the same electric currents in the human brain. In this chapter, we give an overall description of the main principles of MEG and EEG, going deeper into details in the following chapters"--
Author: Risto J. Ilmoniemi Publisher: MIT Press ISBN: 0262039826 Category : Science Languages : en Pages : 257
Book Description
A unified treatment of the generation and analysis of brain-generated electromagnetic fields. In Brain Signals, Risto Ilmoniemi and Jukka Sarvas present the basic physical and mathematical principles of magnetoencephalography (MEG) and electroencephalography (EEG), describing what kind of information is available in the neuroelectromagnetic field and how the measured MEG and EEG signals can be analyzed. Unlike most previous works on these topics, which have been collections of writings by different authors using different conventions, this book presents the material in a unified manner, providing the reader with a thorough understanding of basic principles and a firm basis for analyzing data generated by MEG and EEG. The book first provides a brief introduction to brain states and the early history of EEG and MEG, describes the generation of electromagnetic fields by neuronal activity, and discusses the electromagnetic forward problem. The authors then turn to EEG and MEG analysis, offering a review of linear and matrix algebra and basic statistics needed for analysis of the data, and presenting several analysis methods: dipole fitting; the minimum norm estimate (MNE); beamforming; the multiple signal classification algorithm (MUSIC), including RAP-MUSIC with the RAP dilemma and TRAP-MUSIC, which removes the RAP dilemma; independent component analysis (ICA); and blind source separation (BSS) with joint diagonalization.
Author: Donald L. Schomer Publisher: Lippincott Williams & Wilkins ISBN: 1451153155 Category : Medical Languages : en Pages : 1308
Book Description
The leading reference on electroencephalography since 1982, Niedermeyer's Electroencephalography is now in its thoroughly updated Sixth Edition. An international group of experts provides comprehensive coverage of the neurophysiologic and technical aspects of EEG, evoked potentials, and magnetoencephalography, as well as the clinical applications of these studies in neonates, infants, children, adults, and older adults. This edition's new lead editor, Donald Schomer, MD, has updated the technical information and added a major new chapter on artifacts. Other highlights include complete coverage of EEG in the intensive care unit and new chapters on integrating other recording devices with EEG; transcranial electrical and magnetic stimulation; EEG/TMS in evaluation of cognitive and mood disorders; and sleep in premature infants, children and adolescents, and the elderly. A companion website includes fully searchable text and image bank.
Author: Peter Hansen Publisher: Oxford University Press ISBN: 0199719136 Category : Medical Languages : en Pages : 449
Book Description
Magnetoencephalography (MEG) is an exciting brain imaging technology that allows real-time tracking of neural activity, making it an invaluable tool for advancing our understanding of brain function. In this comprehensive introduction to MEG, Peter Hansen, Morten Kringelbach, and Riitta Salmelin have brought together the leading researchers to provide the basic tools for planning and executing MEG experiments, as well as analyzing and interpreting the resulting data. Chapters on the basics describe the fundamentals of MEG and its instrumentation, and provide guidelines for designing experiments and performing successful measurements. Chapters on data analysis present it in detail, from general concepts and assumptions to analysis of evoked responses and oscillatory background activity. Chapters on solutions propose potential solutions to the inverse problem using techniques such as minimum norm estimates, spatial filters and beamformers. Chapters on combinations elucidate how MEG can be used to complement other neuroimaging techniques. Chapters on applications provide practical examples of how to use MEG to study sensory processing and cognitive tasks, and how MEG can be used in a clinical setting. These chapters form a complete basic reference source for those interested in exploring or already using MEG that will hopefully inspire them to try to develop new, exciting approaches to designing and analyzing their own studies. This book will be a valuable resource for researchers from diverse fields, including neuroimaging, cognitive neuroscience, medical imaging, computer modelling, as well as for clinical practitioners.
Author: G. Buzsáki Publisher: Oxford University Press ISBN: 0199828237 Category : Medical Languages : en Pages : 465
Book Description
Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive "metastable" state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.
Author: Mithun Diwakar
Author: Mithun Diwakar
Author: Andrew C. Papanicolaou
Author: Selma Supek
Author: Roland Lee
Author: Riitta Hari
Author: Risto J. Ilmoniemi
Author: Donald L. Schomer
Author: Peter Hansen
Author: IEEE Engineering in Medicine and Biology Society. Conference
Author: G. Buzsáki