Microbial Stress Responses: Antioxidants, the Plasma Membrane, and Beyond PDF Download

Author: Sukesh Chander Sharma
Publisher: Frontiers Media SA
ISBN: 288974728X
Category : Science
Languages : en
Pages : 149

View

Book Description

Author: Sajad Majeed Zargar
Publisher: Springer
ISBN: 9811074798
Category : Science
Languages : en
Pages : 358

View

Book Description
The natural environment for plants is composed of a complex set of abiotic and biotic stresses; plant responses to these stresses are equally complex. Systems biology allows us to identify regulatory hubs in complex networks. It also examines the molecular “parts” (transcripts, proteins and metabolites) of an organism and attempts to combine them into functional networks or models that effectively describe and predict the dynamic activities of that organism in different environments. This book focuses on research advances regarding plant responses to abiotic stresses, from the physiological level to the molecular level. It highlights new insights gained from the integration of omics datasets and identifies remaining gaps in our knowledge, outlining additional focus areas for future crop improvement research. Plants have evolved a wide range of mechanisms for coping with various abiotic stresses. In many crop plants, the molecular mechanisms involved in a single type of stress tolerance have since been identified; however, in order to arrive at a holistic understanding of major and common events concerning abiotic stresses, the signaling pathways involved must also be elucidated. To date several molecules, like transcription factors and kinases, have been identified as promising candidates that are involved in crosstalk between stress signalling pathways. However, there is a need to better understand the tolerance mechanisms for different abiotic stresses by thoroughly grasping the signalling and sensing mechanisms involved. Accordingly, this book covers a range of topics, including the impacts of different abiotic stresses on plants, the molecular mechanisms leading to tolerance for different abiotic stresses, signaling cascades revealing cross-talk among various abiotic stresses, and elucidation of major candidate molecules that may provide abiotic stress tolerance in plants.

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309069491
Category : Medical
Languages : en
Pages : 530

View

Book Description
This volume is the newest release in the authoritative series of quantitative estimates of nutrient intakes to be used for planning and assessing diets for healthy people. Dietary Reference Intakes (DRIs) is the newest framework for an expanded approach developed by U.S. and Canadian scientists. This book discusses in detail the role of vitamin C, vitamin E, selenium, and the carotenoids in human physiology and health. For each nutrient the committee presents what is known about how it functions in the human body, which factors may affect how it works, and how the nutrient may be related to chronic disease. Dietary Reference Intakes provides reference intakes, such as Recommended Dietary Allowances (RDAs), for use in planning nutritionally adequate diets for different groups based on age and gender, along with a new reference intake, the Tolerable Upper Intake Level (UL), designed to assist an individual in knowing how much is "too much" of a nutrient.

Author: D. K. Choudhary
Publisher: Frontiers Media SA
ISBN: 2832516114
Category : Science
Languages : en
Pages : 260

View

Book Description

Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

View

Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Author: W.Wolfgang Fleischhacker
Publisher: Springer Science & Business Media
ISBN: 9783211838662
Category : Medical
Languages : en
Pages : 164

View

Book Description
Atherosclerosis, the underlying cause of heart attacks, strokes and peripheral vascular disease, is one of the major killers in the world. By 2020 WHO statistics indicate that it will be the most common cause of morbidity and mortality in both the industrialised world and the underdeveloped world. The disease develops slowly over many years in the innermost layer of large and medium-sized arteries (Fig. 1) (Scott, 1995; Ross, 1999; Naumova and Scott, 2000; Glass and Witztum, 2001; Libby, 2001). It does not usually become manifest before the fourth of fifth decade, but then often strikes with devas tating suddenness. Fifty per cent of individuals still die (25 per cent immedi ately) from their first heart attack; and morbidity from coronary heart disease and stroke is very significant. The disease has a profound impact on health care services and on industrial economies. The lesions of atherosclerosis Autopsy studies show that in humans atherosclerosis begins in the first and second decade of life. A similar disease can be produced in experimental animals, where diet and genetics can be manipulated to produce identical lesions. The earliest lesions are fatty streaks. These consist of an accumulation of lipid-engorged macrophages (foam cells) and T and B lymphocytes in the arterial intima. With time, the fatty streaks progress to intermediate lesions, composed of foam cells and smooth muscle cells.

Author: Michel Félétou
Publisher: Morgan & Claypool Publishers
ISBN: 1615041230
Category : Science
Languages : en
Pages : 309

View

Book Description
The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References

Author: R.A.S Hemat
Publisher: Urotext
ISBN: 1903737079
Category : Internal medicine
Languages : en
Pages : 600

View

Book Description
Principles of Modern Urology is an authorative guide to urology and integrated urology. Principles of Modern Urology is an advanced urological textbook. This book begins by showing you how to implement your pathobiology, anatomy and physiology into practical simple approach to every client you meet. This book was written for medical student, resident and professional in medicine and especially urology. The author had adapted his proven teaching strategies into a unique approach that makes integrated urology accessible, and provides the foundations for understanding urology based upon the principles of structural pathobiology. Principles of Modern Urology presents well-integrated and practical approach to most urological condition. It is a versatile retrievable e-book. Principles of Modern Urology provides the reader with current concepts of the pathobiology and interventions for diseases. Anatomy, physiology, and radiology are also included within specific topical chapters. Principles of Modern Urology is based on the extensive international clinical and teaching experience of the author, both in traditional and integrated systems of medical schools.

Author: Arun Shanker
Publisher: BoD – Books on Demand
ISBN: 9533076720
Category : Science
Languages : en
Pages : 362

View

Book Description
Plants, unlike animals, are sessile. This demands that adverse changes in their environment are quickly recognized, distinguished and responded to with suitable reactions. Drought, heat, cold and salinity are among the major abiotic stresses that adversely affect plant growth and productivity. In general, abiotic stress often causes a series of morphological, physiological, biochemical and molecular changes that unfavorably affect plant growth, development and productivity. Drought, salinity, extreme temperatures (cold and heat) and oxidative stress are often interrelated; these conditions singularly or in combination induce cellular damage. To cope with abiotic stresses, of paramount significance is to understand plant responses to abiotic stresses that disturb the homeostatic equilibrium at cellular and molecular level in order to identify a common mechanism for multiple stress tolerance. This multi authored edited compilation attempts to put forth an all-inclusive biochemical and molecular picture in a systems approach wherein mechanism and adaptation aspects of abiotic stress are dealt with. The chief objective of the book hence is to deliver state of the art information for comprehending the effects of abiotic stress in plants at the cellular level.

Author: Tariq Aftab
Publisher: Springer Nature
ISBN: 9811679819
Category : Science
Languages : en
Pages : 458

View

Book Description
This edited book highlights the molecular basis of various enzymatic and non-enzymatic antioxidants, defense mechanisms and adaptation strategies employed by plants to avoid the stressful conditions. Special focus is given to gene expression, omics and other latest technologies such as CRISPR-Cas mediated genome editing applications for defense related studies in plants. Environmental stresses such as drought, salinity or floods etc. induce the generation of reactive oxygen species (ROS) which causes severe damage to cell membrane integrity by accelerating lipid peroxidation. To counteract the detrimental effect of ROS, plants are inherited with an intricate and vibrant antioxidant defense system, comprised of enzymatic (catalase, peroxidase, superoxide dismutase, glutathione reductase, glutathione S-transferase, guaiacol peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase etc.), and non-enzymatic (glutathione, ascorbate, α-tocopherol, carotenoids, flavonoids etc.) antioxidants, which scavenge and/or reduce excess ROS and improve plant tolerance to various stresses. Stress tolerance in most crop plants is positively correlated with an efficient antioxidant system. Therefore, studying the efficiency of antioxidant defense systems in plants is necessary for facilitating the plant’s nature of adaptation against challenging environments. This book is of interest to teachers, researchers and academic experts. Also, the book serves as additional reading material for undergraduate and graduate students of biotechnology and molecular biology of plants.