Methylxanthines PDF Download

Author: Bertil B. Fredholm
Publisher: Springer Science & Business Media
ISBN: 3642134432
Category : Medical
Languages : en
Pages : 566

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Book Description
In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area.

Author: H. C. Andersson
Publisher: Nordic Council of Ministers
ISBN: 9289310987
Category : Medical
Languages : en
Pages : 390

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Book Description
The first part of the report deals with occurrence of methylxanthines in foods, beverages, and medicines, and estimates of caffeine intake. In addition, a short review of the pharmacological and toxicological actions of caffeine is given. The second and main part of the report reviews available information from epidemiological studies on the potential health hazards to the human foetus associated with parental intake during pregnancy of caffeine and related methylxanthines in foods, beverages and medicines. The studied adverse effects are influence on fertility, spontaneous abortion, congenital malformation, pre-term delivery, foetal growth retardation, foetal behaviour and effects on neonates, infants and young children. The conclusion of the report demonstrates the need for limiting caffeine exposure during pregnancy. The Nordic Working Group on Food Toxicology and Risk Evaluation (NNT) recognizes that the human exposure to caffeine and related compounds causes a spectrum of pharmacological effects, for instance cardiovascular, renal, neurological and behavioural effects. The increasing use of caffeine and related methylxanthines in various foods and beverages consumed by children and adolescents cause concern. NNT recommends that a full hazard characterization of caffeine and related methylxanthines should be performed with the aim to reach a conclusion about the upper safe level of intake of these compounds.

Author: J.F. Costello
Publisher: CRC Press
ISBN: 9781850705970
Category : Medical
Languages : en
Pages : 208

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Book Description
This is a technically detailed state-of-the-art text on phosphodiesterase inhibition and the practical applications of theophylline and other phosphodiesterase inhibitors in asthma and chronic obstructive airways disease. It contains important new information on the mechanisms of drug action and on the inhibition of individual isoenzymes of the phosphodiesterase enzyme family as a potentially useful, safe, and non-toxic approach to asthma therapy.

Author: Astrid Nehlig
Publisher: CRC Press
ISBN: 0203618858
Category : Medical
Languages : en
Pages : 251

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Book Description
Coffee, tea, and chocolate are among the most frequently consumed products in the world. The pleasure that many experience from these edibles is accompanied by a range of favorable and adverse effects on the brain that have been the focus of a wealth of recent research. Coffee, Tea, Chocolate, and the Brain presents new information on the

Author: Gene A. Spiller
Publisher: CRC Press
ISBN: 9781420050134
Category : Medical
Languages : en
Pages : 392

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Book Description
Caffeine-found in tea, coffee, mate, cola beverages, cocoa, and chocolate products-is an integral part of the diet of many people. Caffeine answers questions for a broad range of readers interested in the effects beverages and foods containing this dietary methylxanthine have on human health, nutrition, and physiological functioning. The composition, processing, consumption, health effects, and epidemiological correlations of caffeine are examined in detail. It is often said that too much caffeine is "bad for you." How much is too much? Get the facts on consumption of caffeine-containing products with this authoritative text. Chapters 1 and 2 offer an introductory, concise overview of the chemistry and analysis of methylxanthines. In Chapters 3 through 8, each natural product-tea, coffee, mate, and cocoa and chocolate products-is described in terms of botany, cultivation, processing, composition, and consumption patterns. Consumption of caffeine is also examined in detail in Chapter 9. Chapter 10 provides an easy-to-read overview of the basic physiology and biochemistry of caffeine. The ergogenic, cognitive, and emotional effects of caffeine are discussed in Chapters 11 and 12. Chapters 13 through 16 deal with specific health effects-serum cholesterol, cancer and fibrocystic breast disease, calcium and bone health, and human reproduction. For physicians, nutritionists, other health professionals, food scientists, and everyone interested in the effects of caffeine on the human body, Caffeine is a convenient, single-source reference.

Author: Adriana Farah
Publisher: Royal Society of Chemistry
ISBN: 1788016580
Category : Technology & Engineering
Languages : en
Pages : 874

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Book Description
Coffee is one of the most popular drinks in the world but how does the production influence chemistry and quality? This book covers coffee production, quality and chemistry from the plant to the cup. Written by an international collection of contributors in the field who concentrate on coffee research, it is edited expertly to ensure quality of content, consistency and organization across the chapters. Aimed at advanced undergraduates, postgraduates and researchers and accompanied by a sister volume covering how health is influenced by the consumption of coffee, these titles provide an impactful and accessible guide to the current research in the field.

Author: Bennett Alan Weinberg
Publisher: Routledge
ISBN: 1135958173
Category : History
Languages : en
Pages : 428

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Book Description
Caffeine is the world's most popular drug! Almost all of us start our day with a jolt of caffeine from coffee, tea or cola. And many of us crave chocolate when we're stressed or depressed. Without it we're lethargic, head-achy and miserable. Why? Why do we crave caffeine? How much do we really know about our number one drug of choice? Here is the first natural, cultural, and artistic history of our favorite mood enhancer--how it was discovered, its early uses, and the unexpected parts it has played in medicine, religion, painting, poetry, learning, and love. Weinberg and Bealer tell an intriguing story of a remarkable substance that has figured prominently in the exchanges of trade and intelligence among nations and whose most common sources, coffee, tea, and chocolate, have been both promoted as productive of health and creativity and banned as corrupters of the body and mind or subverters of social order. Some Highlights From the World of Caffeine Balzac's addiction to caffeine drove him to eat coffee, as some schizophrenic patients are observed to do today, and may have killed him Mary Tuke breaks the male monopoly on tea in England in 1725 The ways caffeine functions as a smart pill Goethe's responsibility for the discovery of caffeine Did a mini Ice Age help bring coffee, tea and chocolate to popularity in Europe? What is the mystery of coffee's origin? As good as gold: the stories of how caffeine, in its various forms, was used as cash in China, Africa, Central America and Egypt What does the civet cat have to do with the most costly coffee on earth today? The World of Caffeine is a captivating tale of art and society -- from India to Balzac to cybercafes -- and the ultimate caffeine resource.

Author: Solomon Habtemariam
Publisher: Academic Press
ISBN: 0081029233
Category : Medical
Languages : en
Pages : 1180

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Book Description
Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases Examines the pharmacological findings on medicinal foods, including available clinical trials

Author: Magdalena Jeszka-Skowron
Publisher: Springer Nature
ISBN: 303061879X
Category : Technology & Engineering
Languages : en
Pages : 380

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Book Description
Most bioactive compounds have antioxidant activity, particularly tocochromanols, phenolics (flavonoids and phenolic acids), methylxantines and capsaicinoids. Some of these compounds have also other properties important for human health. For example, vitamin E protects against oxidative stress, but it is also known for its “non-antioxidant” functions, including cell signalling and antiproliferation. Selenium compounds and indoleamins are the components of the antioxidant enzymes. Selenium makes vitamin E acquisition easier and controls its physiological functions. In taking part in enzymatic reactions and protecting the cell against free radicals, selenium shows immunomodulative, antiphlogistic, and antiviral activity. Capsaicinoids possess not only antioxidant, but also antibacterial, analgesic, weight-reducing and thermoregulation properties. Studies have also demonstrated their gastroprotective and anticancer properties. Analytical Methods in the Determination of Bioactive Compounds and Elements in Food explores both the influence of particular compounds on human health and the methods used for their determination. Chapters describe various aspects of food and plant analysis, including chromatographic and non‐chromatographic approaches as well as hyphenated techniques. Readers of this book will gain a comprehensive understanding of the important groups of bioactive compounds relevant to human health.

Author: Lippincott Williams & Wilkins
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781792899
Category : Medical
Languages : en
Pages : 740

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Book Description
Written in the award-winning Incredibly Easy! style, this book presents everything the nurse and nursing student needs to know about how drugs act and interact in the treatment of disease. The book focuses on mechanisms of drug action; details specific drugs by pharmacologic class; reviews the nursing process related to each drug category for all body systems, plus pain medications, anti-infective drugs, and cancer drugs; and highlights potentially dangerous interactions, including drug-herb interactions. This thoroughly updated Second edition includes the most current NANDA diagnoses. New chapters cover genitourinary drugs and drugs to treat fluid and electrolyte imbalances. Obesity drugs have been added to the gastrointestinal drugs chapter.