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Author: Curtis D. Klaassen Publisher: CRC Press ISBN: 9780849388323 Category : Medical Languages : en Pages : 436
Book Description
This book brings together work from leading researchers to present the most recent advances in research on metallothionein. This protein interests toxicologists because it is thought that metallothionein protects against metal toxicity and possibly against oxidative stress. It is of interest to pharmacologists because modification of metallothionein levels might have a role in cancer chemotherapy. Nutritionists have an interest in this protein because it appears to be a major storage protein for zinc. Biochemists and molecular biologists will be interested in the mechanisms of regulation of this protein because it is extremely inducible.
Author: Curtis D. Klaassen Publisher: CRC Press ISBN: 9780849388323 Category : Medical Languages : en Pages : 436
Book Description
This book brings together work from leading researchers to present the most recent advances in research on metallothionein. This protein interests toxicologists because it is thought that metallothionein protects against metal toxicity and possibly against oxidative stress. It is of interest to pharmacologists because modification of metallothionein levels might have a role in cancer chemotherapy. Nutritionists have an interest in this protein because it appears to be a major storage protein for zinc. Biochemists and molecular biologists will be interested in the mechanisms of regulation of this protein because it is extremely inducible.
Author: C. Klaasen Publisher: Birkhäuser ISBN: 3034888473 Category : Science Languages : en Pages : 641
Book Description
The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.
Author: Piotr Dziegiel Publisher: Springer ISBN: 3319274724 Category : Science Languages : en Pages : 126
Book Description
This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
Author: Philippe Collery Publisher: John Libbey Eurotext ISBN: 9782742002948 Category : Medical Languages : en Pages : 852
Book Description
The objective of the 6th ISMIBM is to foster exchange of opinions between professionals and specialists working on analysis, research and applications of metal ions, trace elements and minerals in biological, biochemical, medical sciences, toxicology and environmental health. The scientific program, composed of plenary and concurrent sessions, and poster presentations is designed to promote intensive and productive dialogue among experts in these fields. A special program with short courses and mini-symposia have also been organised, featuring specialised areas including toxicology, analysis, pathology, remediation strategies, and environmental medicine. Original contributions (oral and/or poster presentations) are invited on the following themes: Metals and Environmental Health; Molecular Toxicology of Metals; Carcinogenicity of Metals; Speciation of Metals and Other Elements; Uses of Metals in Clinical Applications; Metals and Disease: Environmental and Toxicologic Pathology; Epidemiology and Occupational Health; Metals and Aging; Metals and Homeostasis; Effects of Low and High Nutritional Trace Element Status; Metals and Hormone Actions; Metals and Enzyme Activity; Metals and Chelation Therapy; Health Effects of Arsenic; Risk Assessment of Trace Element Status and Health; Advanced Methods for the Analysis of Trace Elements and Metal Ions.
Author: Paolo Zatta Publisher: World Scientific ISBN: 9812778934 Category : Medical Languages : en Pages : 335
Book Description
Metallothioneins (MTs) represent a large family of proteins characterized by high heavy metal content (mainly CuII and ZnII) and by an unusual cysteine abundance. They have a powerful protective function in all animal tissues, due most likely to their properties as free radical scavengers protecting against oxidative damage. Moreover, the presence and overexpression of MTs in various pathological conditions, such as metal dyshomeostasis, cell proliferation, neurological disorders, and chemotherapy and radiotherapy resistance, could be used as an important prognostic marker, as a histopathological diagnostic tool, and to follow specific pharmacological treatments.This important book explores the role of MTs in the field of neurological disorders (brain inflammation, Alzheimer's and prion diseases, autism, ALS, etc.), cardiology (cardiomyopathy, atherosclerosis), and oncology (melanoma, prostate and breast cancer), through authoritative contributions and a description of basic biochemical information and paradigmatic pathological events.
Author: K.T. Suzuki Publisher: Birkhäuser ISBN: 9783764327699 Category : Science Languages : en Pages : 483
Book Description
Focuses on the biological roles and medical implications of metallothioneins, and related chemical and biochemical developments. The contributors present and discuss findings on the roles of metallothionein in various kinds of stress conditions, including exposure to heavy metals.
Author: Curtis D. Klaassen
Author: Curtis D. Klaassen
Author: M. George Cherian
Author: C. Klaasen
Author: Kazuo T. Suzuki
Author: 
Author: Piotr Dziegiel
Author: Philippe Collery
Author: C Klaasen
Author: Paolo Zatta
Author: K.T. Suzuki