Membranes for Life Sciences PDF Download

Author: Klaus-Viktor Peinemann
Publisher: John Wiley & Sons
ISBN: 3527631372
Category : Technology & Engineering
Languages : en
Pages : 343

View

Book Description
Examining artificial membranes in terms of biocompatibility, drug delivery and controlled release, this book illustrates how existing membrane technologies are being exploited and advanced in emerging medical applications. This work, edited by internationally recognized experts, has author contributions from prominent members of this field who discuss details of all aspects of this technology. This volume provides broad, yet detailed information on synthetic membranes and their applications, including dialysis and artificial kidneys, gas exchange, artificial lungs, devices to assist liver function, and membrane affinity chromatography.

Author: Enrico Drioli
Publisher: Newnes
ISBN: 0080932509
Category : Technology & Engineering
Languages : en
Pages : 1528

View

Book Description
Comprehensive Membrane Science and Engineering, Four Volume Set covers all aspects of membrane science and technology - from basic phenomena to the most advanced applications and future perspectives. Modern membrane engineering is critical to the development of process-intensification strategies and to the stimulation of industrial growth. The work presents researchers and industrial managers with an indispensable tool toward achieving these aims. Covers membrane science theory and economics, as well as applications ranging from chemical purification and natural gas enrichment to potable water Includes contributions and case studies from internationally recognized experts and from up-and-coming researchers working in this multi-billion dollar field Takes a unique, multidisciplinary approach that stimulates research in hybrid technologies for current (and future) life-saving applications (artificial organs, drug delivery)

Author: Mathias Grote
Publisher: University of Chicago Press
ISBN: 022662515X
Category : Science
Languages : en
Pages : 307

View

Book Description
Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing “proton pump inhibitors” or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences—from practitioner to historian to philosopher.

Author: William Stillwell
Publisher: Newnes
ISBN: 0080931286
Category : Science
Languages : en
Pages : 379

View

Book Description
An Introduction to Biological Membranes: From Bilayers to Rafts covers many aspects of membrane structure/function that bridges membrane biophysics and cell biology. Offering cohesive, foundational information, this publication is valuable for advanced undergraduate students, graduate students and membranologists who seek a broad overview of membrane science. Brings together different facets of membrane research in a universally understandable manner Emphasis on the historical development of the field Topics include membrane sugars, membrane models, membrane isolation methods, and membrane transport

Author: Raz Jelinek
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110453908
Category : Technology & Engineering
Languages : en
Pages : 314

View

Book Description
Describes the properties of cellular membranes and their relationship with fundamental biological processes. This book provides insight on the chemistry, structures, model systems, and techniques employed for studying membrane properties and processes. A major focus is on the prominence of membranes in diverse physiological processes and disease, as well as applications of membranes and biomimetic membrane systems in varied disciplines. The book aims to illuminate the significance and beauty of membrane science, and serve both as an entry point for scholars wishing to embark on membrane research, as well as scientists already working in the field.

Author: J. Flinn
Publisher: Springer Science & Business Media
ISBN: 1468418513
Category : Science
Languages : en
Pages : 243

View

Book Description
This book is a collection of papers derived from a conference on membranes held at the Columbus Laboratories of Battelle Memorial Institute in Columbus, Ohio, on October 20 and 21,1969. When a decision is made to sponsor a membrane conference, the problem immediately arises as to what aspect of the technology needs to be emphasized. There were several alternatives from which to choose. The Office of Saline Water, for example, has been sup porting for many years a tremendous volume of research on the desalination of sea and brackish water. In fact, were it not for this effort, the conference which resulted in this book could probably not have been held. Regardless, one could not easily choose to hold a conference on water desalting because the subject is adequately covered in the literature, and yearly conferences are sponsored by the funding agency. Other government agencies, specifically The National Heart and Lung Institutes and The National Institute of Arthritis and Metabolic Diseases, have supported a sizable number of research programs involving the use of membranes for biomedical devices useful in blood oxygenation and kidney augmentation or replacement. Again, these groups have their own outlets for disseminating research results. Still other choices existed among such areas as permeation processes for petroleum separations, advanced or novel membrane process concepts, or characterization of membranes - morphology, permeation prop erties, etc. , - or biological membranes. None of these areas seemed to provide just the right technological emphasis.

Author: Patricia Bassereau
Publisher: Springer
ISBN: 3030006301
Category : Science
Languages : en
Pages : 623

View

Book Description
This book mainly focuses on key aspects of biomembranes that have emerged over the past 15 years. It covers static and dynamic descriptions, as well as modeling for membrane organization and shape at the local and global (at the cell level) scale. It also discusses several new developments in non-equilibrium aspects that have not yet been covered elsewhere. Biological membranes are the seat of interactions between cells and the rest of the world, and internally, they are at the core of complex dynamic reorganizations and chemical reactions. Despite the long tradition of membrane research in biophysics, the physics of cell membranes as well as of biomimetic or synthetic membranes is a rapidly developing field. Though successful books have already been published on this topic over the past decades, none include the most recent advances. Additionally, in this domain, the traditional distinction between biological and physical approaches tends to blur. This book gathers the most recent advances in this area, and will benefit biologists and physicists alike.

Author: Roy J. Levin
Publisher: Butterworth-Heinemann
ISBN: 1483281183
Category : Science
Languages : en
Pages : 183

View

Book Description
The Living Barrier: A Primer on Transfer across Biological Membranes provides information pertinent to the movement of molecules across cell membranes. This book covers a variety of topics, including cell membrane, membrane transfer, water transfer, and movement of charged solutes. Organized into nine chapters, this book begins with an overview of the basic ideas of the cell membrane and reviews the experimental evidence about the structure of the cell membrane. This text then reviews the classical electron microscope pictures of membranes. Other chapters consider the interactions between electrical potentials and the movements of charged substances, which make the membrane transfer of these substances much more complicated than those of neutral molecules. This book discusses as well the aspects of water structure and its influence on membrane permeability. The final chapter deals with the methods by which membranes are synthesized. This book is a valuable resource for biochemists, physiologists, pharmacologists, and botanists.

Author: Chapman
Publisher: Birkhäuser
ISBN: 3034874545
Category : Science
Languages : en
Pages : 351

View

Book Description
It is well known that basic science can trigger an invention of considerable technological and commercial importance. Indeed basic science and invention are often inextricably linked, each being able to catalyse the other. To engender such developments it is important that there should be good communication between the scientist and the technologist. The field of membrane biotechnology is a growing field where such communication is increasingly taking place and where new inventions are occurring. This book provides an overview of this developing field. It contains chapters by scientist and technologists working in the field of Membrane Biotechnology. The chapters cover the latest advances in basic science as well as some recent technological applications. The basic topics include the application of dynamic X-ray diffraction to lipid water systems, FTIR spectroscopy applied to membrane proteins, fluorescent analogues of phosphoinositides, studies of platelet activating factor, antibody binding to model membranes and phospholipase C induced fusion. The technological topics described include the development of new haemocompatible materials based upon biomembrane mimicry, new lung surfactant materials, drug delivery systems including liposomes and the development of new biosensors including Langmuir Blodgett films. The meeting showed that there are many other useful applications in the pipeline. The potential for new polymeric drug delivery systems, of ion selective systems based on the knowledge of ion-channel protein structures, of new plastics for cell growth and cellular engineering for artificial organs. These are among the interesting developments that are emerging in this field.

Author: Kenneth M. Merz
Publisher: Springer Science & Business Media
ISBN: 1468485806
Category : Science
Languages : en
Pages : 596

View

Book Description
The interface between a living cell and the surrounding world plays a critical role in numerous complex biological processes. Sperm/egg fusion, virus/cell fusion, exocytosis, endocytosis, and ion permeation are a few examples of processes involving membranes. In recent years, powerful tools such as X-ray crystal lography, electron microscopy, nuclear magnetic resonance, and infra-red and Raman spectroscopy have been developed to characterize the structure and dy namics of biomembranes. Despite this progress, many of the factors responsible for the function of biomembranes are still not well understood. The membrane is a very complicated supramolecular liquid-crystalline structure that is largely composed of lipids, forming a bilayer, to which proteins and other biomolecules are anchored. Often, the lipid bilayer environment is pictured as a hydropho bic structureless slab providing a thermodynamic driving force to partition the amino acids of a membrane protein according to their solubility. However, much of the molecular complexity of the phospholipid bilayer environment is ignored in such a simplified view. It is likely that the atomic details of the polar head group region and the transition from the bulk water to the hydrophobic core of the membrane are important. An understanding of the factors responsible for the function of biomembranes thus requires a better characterization at the molec ular level of how proteins interact with lipid molecules, of how lipids affect protein structure and of how lipid molecules might regulate protein function.