Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery PDF full book. Access full book title Mechanisms of Sepsis-Induced Organ Dysfunction and Recovery by E. Abraham. Download full books in PDF and EPUB format.
Author: E. Abraham Publisher: Springer Science & Business Media ISBN: 9783540301585 Category : Medical Languages : en Pages : 476
Book Description
There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.
Author: E. Abraham Publisher: Springer Science & Business Media ISBN: 9783540301585 Category : Medical Languages : en Pages : 476
Book Description
There have been tremendous advances in understanding the cellular mechanisms involved in sepsis and contributing to the development of multiple organ dysfunction and mortality in this setting. The chapters in this book provide up-to-date insights into important pathways that are initiated by sepsis.
Author: Sadis Matalon Publisher: IOS Press ISBN: 9781586031831 Category : Medical Languages : en Pages : 320
Book Description
This book contains contributions of internationally known basic scientists and clinicians with expertise in various aspects of lung injury and repair. This monogram on the pathophysiology and treatment of Acute Lung Injury contains five different sections, each one with contributions from both basic and clinical scientists, outlining existing controversies, an how they can be resolved by future multidisciplinary studies. The various sections discuss: sodium transport and fluid clearance across the normal and injured lungs, the role of the pulmonary surfactant in the pathogenesis and treatment of ARDS, mechanisms and modification of acute and chronic lung injury, ventilatory strategies for the management of acute respiratory distress syndrome and nitric oxide: friend or foe.
Author: Bruce D. Spiess Publisher: ISBN: Category : Medical Languages : en Pages : 264
Book Description
This text takes a close look at the interaction of the facets within the circulatory system to find an understanding of the deviations of homeostatis caused by Cardiopulmonary bypass (CPB). It also examines possible future developments to help clinicians predict individual reactions to CPB.
Author: Israel Vlodavsky Publisher: Springer Nature ISBN: 3030345211 Category : Medical Languages : en Pages : 871
Book Description
Written by internationally recognized leaders in Heparanase biology, the book’s eight chapters offer an opportunity for scientists, clinicians and advanced students in cell biology, tumor biology and oncology to obtain a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications. Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.
Author: Hector R. Wong Publisher: Springer Science & Business Media ISBN: 1461514274 Category : Medical Languages : en Pages : 329
Book Description
Acute lung injury (ALI) impacts patient care in every ICU in the world. Our collective understanding of this condition has grown immensely over the past decade but morbidity and mortality remain unacceptably high. To enhance the understanding of clinicians and researchers, this book addresses the pathophysiology of acute lung injury from a molecular and cellular standpoint; includes animal models of acute lung injury and points to potential therapeutic advances based on scientific findings. It is a concise compendium of the multiple pathways, mechanisms and molecules involved in the pathophysiology of acute lung injury and is intended to help caregivers understand the process and thus care for patients more effectively.
Author: Lawrence H. Lash Publisher: Elsevier ISBN: 1483218619 Category : Science Languages : en Pages : 527
Book Description
Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Author: Sergei P. Atamas Publisher: BioBitField ISBN: 0982956916 Category : Medical Languages : en Pages : 60
Book Description
The conference focused on pathophysiologic mechanisms, as well as diagnostic approaches to and care for patients with diffuse parenchymal disease. The conference brought together experts from various fields of research in pulmonary fibrosis, and allowed for cross-dissemination of ideas and experiences. 58 pages, perfect binding. Published by BioBitField, P.O. Box 1816, Ellicott City, MD 21041-1816, U.S.A. Table of Contents: 1. Sergei P. Atamas and Jeffrey D. Hasday.2009 Hales Lung Conference: Clinical and Pathophysiologic Aspects of Diffuse Parenchymal Lung Disease. 2. Richard P. Phipps, Geniece M. Lehmann, and Patricia J. Sime. Lung Fibrosis: the Impact of Fibroblast Diversity and Differentiation. 3. Jonathan K. Alder and Mary Armanios. Idiopathic Pulmonary Fibrosis as a Disease of Aging: the Connection to Short Telomeres. 4. Sem H. Phan. Induction of Telomerase in Pulmonary Fibrosis. 5. Cory M. Hogaboam. On the Clinical Progression of IPF: Can We Blame the Innate Immune System? 6. Irina G. Luzina and Sergei P. Atamas. The Integrin-Mediated Profibrotic Effect of T Lymphocytes. 7. Patricia J. Sime, Thomas H. Thatcher, Ajit Kulkarni, and Richard P. Phipps. Stamping Out the Fires of Lung Inflammation: a Role for the Aryl Hydrocarbon Receptor. 8. Rose M. Viscardi. Ureaplasma Intrauterine Infection: Evidence for its Role in BPD Pathogenesis in Preterm Infants. 9. Timothy S. Blackwell and William E. Lawson. Impact of ER Stress and Apoptosis of Epithelial Cells on Pulmonary Fibrosis. 10. Jeffrey R. Galvin, Aletta A. Frazier, and Teri J. Franks. Lung Fibrosis Pathogenesis from the Clinical Perspective: Collaborative Radiologic and Histologic Assessment of Fibrotic Lung Disease.
Author: E. Abraham
Author: E. Abraham
Author: 
Author: Sadis Matalon
Author: Ewald R. Weibel
Author: Bruce D. Spiess
Author: Israel Vlodavsky
Author: Hector R. Wong
Author: Christoph Thiemermann
Author: Lawrence H. Lash
Author: Sergei P. Atamas