Mathematical Models of Retinal Development PDF Download

Author: Giovanna Guidoboni
Publisher: Springer Nature
ISBN: 3030258866
Category : Mathematics
Languages : en
Pages : 606

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Book Description
The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical modeling. Because each fluid receives a thorough analysis from experts in their respective fields, this volume stands out among the existing ophthalmology literature. Ocular Fluid Dynamics is ideal for current and future graduate students in applied mathematics and ophthalmology who wish to explore the field by investigating open questions, experimental technologies, and mathematical models. It will also be a valuable resource for researchers in mathematics, engineering, physics, computer science, chemistry, ophthalmology, and more.

Author: Erika Tatiana Camacho
Publisher:
ISBN:
Category :
Languages : en
Pages : 280

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Book Description

Author: R. Collins
Publisher: Springer Science & Business Media
ISBN: 3642501532
Category : Mathematics
Languages : en
Pages : 111

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Book Description
A rich and abundant literature has developed during the last half century dealing with mechanical aspects of the eye, mainly from clinical and, experimental points of view. For the most part, workers have attempted to shed light on the complex set of conditions known by the general term glaucoma. These conditions are characterised by an increase in intraocular pressure sufficient to cause de generation of the optic disc and concomitant defects in the visual field, which, if not controlled, lead to inevitable permanent blindness. In the United States alone, an estimated 50,000 persons are blind as a result of glaucoma, which strikes about 2% of the population over 40 years of age (Vaughan and Asbury, 1974). An understanding of the underlying mechanisms of glaucoma is hindered by the fact that elevated intraocular pressure, like a runny nose, is but a symptom which may have a variety of causes. Only by turning to the initial pathology can one hope to understand this important class of medical problems.

Author: Jean Petitot
Publisher: Springer
ISBN: 3319655914
Category : Mathematics
Languages : en
Pages : 388

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Book Description
This book describes several mathematical models of the primary visual cortex, referring them to a vast ensemble of experimental data and putting forward an original geometrical model for its functional architecture, that is, the highly specific organization of its neural connections. The book spells out the geometrical algorithms implemented by this functional architecture, or put another way, the “neurogeometry” immanent in visual perception. Focusing on the neural origins of our spatial representations, it demonstrates three things: firstly, the way the visual neurons filter the optical signal is closely related to a wavelet analysis; secondly, the contact structure of the 1-jets of the curves in the plane (the retinal plane here) is implemented by the cortical functional architecture; and lastly, the visual algorithms for integrating contours from what may be rather incomplete sensory data can be modelled by the sub-Riemannian geometry associated with this contact structure. As such, it provides readers with the first systematic interpretation of a number of important neurophysiological observations in a well-defined mathematical framework. The book’s neuromathematical exploration appeals to graduate students and researchers in integrative-functional-cognitive neuroscience with a good mathematical background, as well as those in applied mathematics with an interest in neurophysiology.

Author: E. Y. K. Ng
Publisher: CRC Press
ISBN: 1439869936
Category : Technology & Engineering
Languages : en
Pages : 432

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Book Description
Advanced image processing and mathematical modeling techniques are increasingly being used for the early diagnosis of eye diseases. A comprehensive review of the field, Human Eye Imaging and Modeling details the latest advances and analytical techniques in ocular imaging and modeling. The first part of the book looks at imaging of the fundus as well as infrared imaging. It begins by exploring developments in the analysis of fundus images, particularly for the diagnosis of diabetic retinopathy and glaucoma. It also reviews anterior segment imaging and reports on developments in ocular thermography, especially the use of thermal imaging as the basis of tear evaporimetry and dry eye diagnosis. The second part of the book delves into mathematical modeling of the human eye. Coverage includes modeling of the eye during retinal laser surgery, a framework for optical simulation, heat distribution using a 3D web-splines solution, and exposure to laser radiation. The text also examines computer simulation of the human eye based on principles of heat transfer, as well as various bioheat equations to predict interior temperatures based on the surface temperature. Featuring contributions by established experts in eye imaging, this is a valuable reference for medical personnel and researchers who want to know more about state-of-the-art computer-based imaging and detection methods. It presents novel imaging and modeling algorithms that can aid in early diagnosis, with the aim of enriching the lives of people suffering from eye abnormalities.

Author: Stephen A. Wirkus
Publisher: CRC Press
ISBN: 1498736068
Category : Mathematics
Languages : en
Pages : 788

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Book Description
A Course in Differential Equations with Boundary Value Problems, 2nd Edition adds additional content to the author’s successful A Course on Ordinary Differential Equations, 2nd Edition. This text addresses the need when the course is expanded. The focus of the text is on applications and methods of solution, both analytical and numerical, with emphasis on methods used in the typical engineering, physics, or mathematics student’s field of study. The text provides sufficient problems so that even the pure math major will be sufficiently challenged. The authors offer a very flexible text to meet a variety of approaches, including a traditional course on the topic. The text can be used in courses when partial differential equations replaces Laplace transforms. There is sufficient linear algebra in the text so that it can be used for a course that combines differential equations and linear algebra. Most significantly, computer labs are given in MATLAB®, Mathematica®, and MapleTM. The book may be used for a course to introduce and equip the student with a knowledge of the given software. Sample course outlines are included. Features MATLAB®, Mathematica®, and MapleTM are incorporated at the end of each chapter All three software packages have parallel code and exercises There are numerous problems of varying difficulty for both the applied and pure math major, as well as problems for engineering, physical science and other students. An appendix that gives the reader a "crash course" in the three software packages Chapter reviews at the end of each chapter to help the students review Projects at the end of each chapter that go into detail about certain topics and introduce new topics that the students are now ready to see Answers to most of the odd problems in the back of the book

Author: Robert B. Northrop
Publisher: CRC Press
ISBN: 142004172X
Category : Medical
Languages : en
Pages : 490

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Book Description
Although neural modeling has a long history, most of the texts available on the subject are quite limited in scope, dealing primarily with the simulation of large-scale biological neural networks applicable to describing brain function. Introduction to Dynamic Modeling of Neuro-Sensory Systems presents the mathematical tools and methods that can de

Author: Stephen A. Wirkus
Publisher: CRC Press
ISBN: 1466509104
Category : Mathematics
Languages : en
Pages : 801

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Book Description
A Course in Ordinary Differential Equations, Second Edition teaches students how to use analytical and numerical solution methods in typical engineering, physics, and mathematics applications. Lauded for its extensive computer code and student-friendly approach, the first edition of this popular textbook was the first on ordinary differential equations (ODEs) to include instructions on using MATLAB®, Mathematica®, and MapleTM. This second edition reflects the feedback of students and professors who used the first edition in the classroom. New to the Second Edition Moves the computer codes to Computer Labs at the end of each chapter, which gives professors flexibility in using the technology Covers linear systems in their entirety before addressing applications to nonlinear systems Incorporates the latest versions of MATLAB, Maple, and Mathematica Includes new sections on complex variables, the exponential response formula for solving nonhomogeneous equations, forced vibrations, and nondimensionalization Highlights new applications and modeling in many fields Presents exercise sets that progress in difficulty Contains color graphs to help students better understand crucial concepts in ODEs Provides updated and expanded projects in each chapter Suitable for a first undergraduate course, the book includes all the basics necessary to prepare students for their future studies in mathematics, engineering, and the sciences. It presents the syntax from MATLAB, Maple, and Mathematica to give students a better grasp of the theory and gain more insight into real-world problems. Along with covering traditional topics, the text describes a number of modern topics, such as direction fields, phase lines, the Runge-Kutta method, and epidemiological and ecological models. It also explains concepts from linear algebra so that students acquire a thorough understanding of differential equations.

Author: Riccardo Sacco
Publisher: Academic Press
ISBN: 0128125195
Category : Technology & Engineering
Languages : en
Pages : 856

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Book Description
A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions. - Presents theoretical (modeling), biological (experimental), and computational (simulation) perspectives - Features examples, exercises, and MATLAB codes for further reader involvement - Covers basic and advanced functional and computational techniques throughout the book

Author: Professor Vasilis Z. Marmarelis
Publisher: John Wiley & Sons
ISBN: 9780471469605
Category : Medical
Languages : en
Pages : 564

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Book Description
The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.