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Author: Karoly Vekey Publisher: Elsevier ISBN: 0080554652 Category : Science Languages : en Pages : 607
Book Description
Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.
Author: Karoly Vekey Publisher: Elsevier ISBN: 0080554652 Category : Science Languages : en Pages : 607
Book Description
Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine.The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging.* Provides a broad look at how the medical field is benefiting from advances in mass spectrometry.* Guides the reader from basic principles and methods to cutting edge applications.* There is NO comparable book on the market to fill this fast growing field.
Author: John R. de Laeter Publisher: John Wiley & Sons ISBN: 9780471345398 Category : Science Languages : en Pages : 506
Book Description
Seit über 50 Jahren gehört die Massenspektrometrie zu den wichtigsten analytischen Methoden. Neben einem technologiehistorischen Überblick konzentriert sich dieser Band auf die Analytik von Metallen und Elementen. Beschrieben werden Anwendungen aus der Meteorologie, Kerntechnik, Astrochemie, Geowissenschaft und Umwelttechnik. Dabei wird auf zahlreiche spezielle Verfahren eingegangen, u.a. auf die Sektorfeld- und die Sekundärionen-MS, auf induktiv gekoppelte Plasmen und beschleunigergestützte MS. Erläutert werden auch Isotopenverfahren zur Altersbestimmung von Proben.
Author: Agnieszka Kraj Publisher: John Wiley & Sons ISBN: 047039580X Category : Science Languages : en Pages : 358
Book Description
With contributions from noted experts from Europe and North America, Mass Spectrometry Instrumentation, Interpretation, and Applications serves as a forum to introduce students to the whole world of mass spectrometry and to the many different perspectives that each scientific field brings to its use. The book emphasizes the use of this important analytical technique in many different fields, including applications for organic and inorganic chemistry, forensic science, biotechnology, and many other areas. After describing the history of mass spectrometry, the book moves on to discuss instrumentation, theory, and basic applications.
Author: Oscar Alzate Publisher: CRC Press ISBN: 1420076264 Category : Medical Languages : en Pages : 356
Book Description
In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg
Author: J. D. Waldron Publisher: Elsevier ISBN: 1483184412 Category : Science Languages : en Pages : 721
Book Description
Advances in Mass Spectrometry documents the proceedings of a Joint Conference on Mass Spectrometry held at the University of London, Great Britain on September 24-26, 1958. This compilation reviews the instruments, techniques, applications, and major developments in mass spectrometry over the past years. The topics discussed include the performance and image error correction of the new stigmatic focusing mass spectrograph; correction of second order aberrations in inhomogeneous magnetic sector fields; and high sensitivity solid source mass spectrometry. The isotope dilution analysis; digitization of mass spectra; ionization potentials of alkyl and halogenated alkyl free radicals; and negative ion formation and electric breakdown in some halogenated gases are also elaborated. This book likewise covers the mass spectrometer as a geological instrument and absorption and desorption of gases in the ionized state on metal and glass surfaces. This publication is a useful reference to students and researchers conducting work on mass spectrometry.
Author: Philip F. Kane Publisher: Springer Science & Business Media ISBN: 1461344905 Category : Technology & Engineering Languages : en Pages : 675
Book Description
Until comparatively recently, trace analysis techniques were in general directed toward the determination of impurities in bulk materials. Methods were developed for very high relative sensitivity, and the values determined were average values. Sampling procedures were devised which eliminated the so-called sampling error. However, in the last decade or so, a number of developments have shown that, for many purposes, the distribution of defects within a material can confer important new properties on the material. Perhaps the most striking example of this is given by semiconductors; a whole new industry has emerged in barely twenty years based entirely on the controlled distribu tion of defects within what a few years before would have been regarded as a pure, homogeneous crystal. Other examples exist in biochemistry, metallurgy, polyiners and, of course, catalysis. In addition to this of the importance of distribution, there has also been a recognition growing awareness that physical defects are as important as chemical defects. (We are, of course, using the word defect to imply some dis continuity in the material, and not in any derogatory sense. ) This broadening of the field of interest led the Materials Advisory Board( I} to recommend a new definition for the discipline, "Materials Character ization," to encompass this wider concept of the determination of the structure and composition of materials. In characterizing a material, perhaps the most important special area of interest is the surface.
Author: Sabine Becker Publisher: John Wiley & Sons ISBN: 9780470517208 Category : Science Languages : en Pages : 514
Book Description
Providing an exhaustive review of this topic, Inorganic Mass Spectrometry: Principles and Applications provides details on all aspects of inorganic mass spectrometry, from a historical overview of the topic to the principles and functions of mass separation and ion detection systems. Offering a comprehensive treatment of inorganic mass spectrometry, topics covered include: Recent developments in instrumentation Developing analytical techniques for measurements of trace and ultratrace impurities in different materials This broad textbook in inorganic mass spectrometry, presents the most important mass spectrometric techniques used in all fields of analytical chemistry. By covering recent developments and advances in all fields of inorganic mass spectrometry, this text provides researchers and students with information to answer any questions on this topic as well as providing the basic fundamentals for understanding this potentially complex, but increasingly relevant subject.
Author: Despina Tsipi Publisher: John Wiley & Sons ISBN: 1119070007 Category : Science Languages : en Pages : 288
Book Description
Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites. Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in combination with MS for the analysis of pesticides Describes various established and new ionization techniques as well as the main MS platforms, software tools and mass spectral libraries
Author: Karoly Vekey
Author: Karoly Vekey
Author: Chester R. Fultz
Author: John R. de Laeter
Author: Agnieszka Kraj
Author: Oscar Alzate
Author: J. D. Waldron
Author: 
Author: Philip F. Kane
Author: Sabine Becker
Author: Despina Tsipi