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Author: Michael L. Grossbard Publisher: PMPH-USA ISBN: 9781550091526 Category : Lymphomas Languages : en Pages : 488
Book Description
Malignant Lymphomas ACS American Cancer Society Atlas of Clinical Oncology Malignant Lymphomas is a volume in the acclaimed American Cancer Society Atlas of Clinical Oncology series. Dr. Grossbard and his team have summarized current knowledge on the pathology, epidemiology, molecular biology, presentation and management of ......
Author: Michael L. Grossbard Publisher: PMPH-USA ISBN: 9781550091526 Category : Lymphomas Languages : en Pages : 488
Book Description
Malignant Lymphomas ACS American Cancer Society Atlas of Clinical Oncology Malignant Lymphomas is a volume in the acclaimed American Cancer Society Atlas of Clinical Oncology series. Dr. Grossbard and his team have summarized current knowledge on the pathology, epidemiology, molecular biology, presentation and management of ......
Author: Karl Lennert Publisher: Springer ISBN: 9783540080206 Category : Medical Languages : en Pages : 836
Book Description
A.G. STANSFELD, and J.A.M. VAN UNNIK. In joint discussions in 1974, the Club worked out a new terminology that was acceptable to all members and will hopefully be acceptable to other pathologists. Since then, it has been called the Kiel Classification. We are also pleased that the clinicians belonging to the Kiel Lymphoma Study Group-foremost A. STACHER and G. BRITTINGER have been able to present preliminary data on the clinical relevance of the new classification. Finally, our optimism was fortified by the findings of R.J. LUKES and R.D. COLLINS, which largely concur with ours in both concept and practical significance. This book is divided into six main sections. First, there is a chapter on normal cytology that supplements and, in some respects, revises the presentation given in Part A of this Handbook (1961). H.K. MULLER-HERMELINK played a major role in the writing of the first chapter. The second chapter is a brief description of the light-microscopic techniques that are used in our laboratories and have proved to be suitable for a precise diagnosis of lymph-node diseases.
Author: Bruce W. Dana Publisher: Springer Science & Business Media ISBN: 1461530849 Category : Medical Languages : en Pages : 248
Book Description
This volume is intended to present an eclectic selection of informative reviews on aspects of the malignant lymphomas, including Hodgkin's disease. The choice of suitable review topics in this field is made hazardous by several facts. First, the growth of insight into basic mechanisms of lymphomagenesis is explosive, as is the expansion of our understanding of the need for precise morphologic classification of these diseases. Second, new therapeutic agents, cytotoxic and biologic, as well as new drug delivery strategies, are appearing with remarkable frequency. Finally, old "standard" approaches, such as the staging laparotomy for Hodgkin's disease, are being reconsidered and deserve attention in an up-to-date collection of papers. The 10 reviews presented here fall generally into three categories. First, the optimal diagnostic and therapeutic approaches to Hodgkin's disease are considered by Mark Leibenhaut, who reviews the status of the diagnostic staging laparotomy, and by Philip Bierman, who discusses his thoughts on the timing of high-dose treatment with bone marrow transplantation for this disease. There follow four reviews of current management of specific histologic subtypes of malignant lymphoma. First, Velasquez reviews prognostic factors in both intermediate and high grade lymphomas. Miller and Dahlberg review and update the Southwest Oncology Group experience in developing curative cytotoxic combination therapies for diffuse large-cell lymphomas. Lastly, optimal therapy for two kinds of high grade lymphoma are presented. Butler and Hainsworth describe the Vanderbilt experience with diffuse small noncleaved cell lymphoma and Picozzi reviews lymphoblastic lymphoma.
Author: M. L. Jacobs Publisher: Springer Science & Business Media ISBN: 3642999506 Category : Medical Languages : en Pages : 56
Book Description
Over the years, the management of lymphomatous disease has followed a general trend from the purely empirical and intuitive use of medications to radiation, to surgery, and to chemotherapy with alkylating agents and anti-metabolites. In the 20th century, the treatment of these diseases has been predominantly by radiation. As radiology emerged from ROENTGEN'S original work to the sophisticated science of the present, the radiological equipment, which had been crude and inaccurate, evolved into mechanical and electronic instruments of enormous complexity and capable of great accuracy. The progress and success of radiation therapy for malig nant disease paralleled the technical development of the devices employed. For this reason, the chronology of the parallel development is given in detail. The gross and histologic descriptions of the lymphomas, from 1832 to the present, are voluminous and controversial. Therefore the pathology is reviewed and these diseases classified before reviewing therapy of the lymphomas. I. Hodgkin's Disease 1. Pathology and Classification The current classification of the so-called lymphomata into HODGKIN'S disease, lymphosarcoma, and reticulum cell sarcoma is modern. Any historical or scientific review of ,the subject rightfully begins with a discussion of HODGKIN'S original paper entitled "On Some Morbid Appearances of the Absorbent Glands and Spleen" published in 1832. This classical report describes the clinical and gross pathologic findings in a group of patients whose symptomatology presented striking similarities; notably enlargement of peripheral lymph nodes in the neck, the axillae, and the groin and, frequently, enlargement of the mediastinal nodes.
Author: K. Musshoff Publisher: Springer Science & Business Media ISBN: 3642808298 Category : Medical Languages : en Pages : 301
Book Description
K. MUSSHOFF The group of diseases known as malignant lymphomas are, for a number of reasons, of equal interest to theoretical and clinical medicine. New findings in the fields of virology and immunology could conceivably shed some light on the so far unknown etiology of malignant lymphomas. A viral etiology could explain many of the dis parate findings with such a puzzling disease as lymphogranulomatosis, which shows both all the signs of malignancy, such as the characteristic Reed-Sternberg and Hodgkin cells and chromosome abnormalities, and those of an inflammatory disease, i.e. typical changes in the blood count and bone marrow and in the distribution of serum proteins. So far we have not been able to identify the etiology of this disease. However, clinical observations and pathomorphological investigations involving a joint effort by different branches of medicine have brought us closer to an understanding of the clinical picture. Descriptive anatomy has given us a clear picture of the regional distribution of the lymphatic system, which has long been neglected in the past. The introductory paper by Dr. S. KUBIK (Zurich), who has made valuable contributions to our knowl edge of the anatomy of the lymphatic system, deals with this subject.
Author: Georg Lenz Publisher: Walter de Gruyter GmbH & Co KG ISBN: 3110366916 Category : Medical Languages : en Pages : 426
Book Description
This book is an up to date compendium on the biology and molecular pathogenesis of lymphomas, which represent malignant cancers of the lymphoid system. With its focus on the biology and genetic basis of these diseases, the book is of interest to basic scientists, biologists, clinical hematologists and pathologists as well as medical students. Different chapters will cover all major lymphoma subtypes, as well as chronic lymphocytic leukemia and selected less common lymphoma entities such as T-cell lymphomas and central nervous system lymphomas.
Author: G.A. Pangalis Publisher: Springer Science & Business Media ISBN: 3642799132 Category : Medical Languages : en Pages : 188
Book Description
In the last few years a good deal of information related to the biology and treatment of malignant lymphomas has been accumulated and published in journals and monographs. There is, however, no book that gives a concise and objective update of this information or presents a general survey of the subject. The contributors to this book are international authorities, and on the basis of their personal experience and data from the literature they have written a high-level update on malignant lymphomas which will be of interest to both specialists and nonspecialists.
Author: Karl Lennert Publisher: Springer Science & Business Media ISBN: 3642810926 Category : Medical Languages : en Pages : 843
Book Description
A.G. STANSFELD, and J.A.M. VAN UNNIK. In joint discussions in 1974, the Club worked out a new terminology that was acceptable to all members and will hopefully be acceptable to other pathologists. Since then, it has been called the Kiel Classification. We are also pleased that the clinicians belonging to the Kiel Lymphoma Study Group-foremost A. STACHER and G. BRITTINGER have been able to present preliminary data on the clinical relevance of the new classification. Finally, our optimism was fortified by the findings of R.J. LUKES and R.D. COLLINS, which largely concur with ours in both concept and practical significance. This book is divided into six main sections. First, there is a chapter on normal cytology that supplements and, in some respects, revises the presentation given in Part A of this Handbook (1961). H.K. MULLER-HERMELINK played a major role in the writing of the first chapter. The second chapter is a brief description of the light-microscopic techniques that are used in our laboratories and have proved to be suitable for a precise diagnosis of lymph-node diseases.
Author: K. Jellinger Publisher: Springer Science & Business Media ISBN: 3662084562 Category : Medical Languages : en Pages : 290
Book Description
More than 150 years have passed since involvement of the nervous system in leukemia was first reported by BURNS, while the possibility of the primary brain tumor derived from the lymphoreticular tissue was recognized much later. BAILEY in 1929 described such neoplasms under the term perithelial sarcoma. Later these tumors of the nervous system have been variously designated as "Perivascular of perithelial sarcomas, reticulum cell sarcomas or microgliomas", as controversy has evolved and still exists on the definition of this group of neoplasms and on the nature of their cells of origin. Much of the unfortunate confusion concerning the neoplastic lesions attributed to "microglia" and other derivations of the RE system arose because their close relationship to extra neural cells has been ignored. On the other hand, communication in the field of malignant lymphomas has become increasingly difficult because of the termino logic maze and conceptual diversities of traditional morphological classifica tions that have limited valid comparisons. Although at present we are still far from a precise recognition of the basic features of lymphoproliferative processes and from a fairly general agreement on the terminology of non-Hodgkin lymphomas, there is encouraging evidence recently of some enlightment on the nature of tumor cells that provides the basis for a reasonable and generally acceptable lymphoma classification.
Author: Franco Cavalli Publisher: Springer Science & Business Media ISBN: 1461326079 Category : Medical Languages : en Pages : 644
Book Description
Malignant lymphomas remain a fascinating research topic for clinicians as well as basic scientists. Rapidly increasing technical sophistication, ex panded knowledge and broader implications of new findings underline the need for a forum to integrate the latest developments in the multiple areas involved in the challenging study of lymphoid malignancies. This volume includes contributions of renowned experts and is based on a selection of papers presented at the Second International Conference on Malignant Lymphomas that was held in Lugano, Switzerland, in June 1984. Updated information is provided on various experimental fields including cell biolo gy, immunology, genetics and cell biochemistry. Particular attention has been given to special clinical entities such as the lymphomas associated with the Acquired Immune Deficiency Syndrome. Recent advances in the treat of Hodgkin's disease, ncin-Hodgkin's lymphomas and childhood lym ment phomas are highlighted with emphasis on growing experience with new therapeutic approaches including monoclonal antibodies and bone marrow transplantation. The contents of the volume reflect and translate numerous avenues of exploration. While there might be some unavoidable overlap, most appear essentially complementary. The intent of the Program Committee of the Second International Conference on Malignant Lymphomas was to promote further interactions between all those who are devoting major efforts to elucidate the nature of these diseases or their optimal therapy. This volume will hopefully amplify this objective. The Editors wish to thank the contributors for delivering the manuscripts on schedule.
Author: Michael L. Grossbard
Author: Michael L. Grossbard
Author: Karl Lennert
Author: Bruce W. Dana
Author: M. L. Jacobs
Author: K. Musshoff
Author: Georg Lenz
Author: G.A. Pangalis
Author: Karl Lennert
Author: K. Jellinger
Author: Franco Cavalli