Author: Nianrong Sun
Publisher: World Scientific
ISBN: 9811230560
Category : Science
Languages : en
Pages : 632
Book Description
Proteomics is a study which takes the existence and activities of all proteins in cells as the research object for a more in-depth understanding of the laws of life activity. Since the concept of proteome was proposed in 1995, proteomics has achieved rapid development during the past decades. As a significant part of post-genomics, proteomics has strengthened its position and also become the forefront of scientific research in this century. Magnetic nanomaterials in proteomics analysis is an interdisciplinary field combining magnetic nanomaterials science and proteomics. From the current research, magnetic nanomaterials have shown great potential in complex proteomics research.This book focuses on the application of magnetic nanomaterials in the forefront of proteomics research, and describes in details the synthetic methods, properties, principles and performance of magnetic nanomaterials in various branches of proteomics, which includes digestion studies, enrichment of low abundance peptides, as well as the analysis of phosphoprotein and glycoprotein. Past 10 years' research on magnetic materials in proteomics is integrated, and then the application of magnetic nanomaterials in proteomics analysis are stated systematically.This book can serve as reference book for teaching in the major of proteomics analysis, and also can be reference book for researchers who are studying materials for proteomics.
Magnetic Micro-/nano-materials For Proteomics Analysis
Author: Nianrong Sun
Publisher: World Scientific
ISBN: 9811230560
Category : Science
Languages : en
Pages : 632
Book Description
Proteomics is a study which takes the existence and activities of all proteins in cells as the research object for a more in-depth understanding of the laws of life activity. Since the concept of proteome was proposed in 1995, proteomics has achieved rapid development during the past decades. As a significant part of post-genomics, proteomics has strengthened its position and also become the forefront of scientific research in this century. Magnetic nanomaterials in proteomics analysis is an interdisciplinary field combining magnetic nanomaterials science and proteomics. From the current research, magnetic nanomaterials have shown great potential in complex proteomics research.This book focuses on the application of magnetic nanomaterials in the forefront of proteomics research, and describes in details the synthetic methods, properties, principles and performance of magnetic nanomaterials in various branches of proteomics, which includes digestion studies, enrichment of low abundance peptides, as well as the analysis of phosphoprotein and glycoprotein. Past 10 years' research on magnetic materials in proteomics is integrated, and then the application of magnetic nanomaterials in proteomics analysis are stated systematically.This book can serve as reference book for teaching in the major of proteomics analysis, and also can be reference book for researchers who are studying materials for proteomics.
Publisher: World Scientific
ISBN: 9811230560
Category : Science
Languages : en
Pages : 632
Book Description
Proteomics is a study which takes the existence and activities of all proteins in cells as the research object for a more in-depth understanding of the laws of life activity. Since the concept of proteome was proposed in 1995, proteomics has achieved rapid development during the past decades. As a significant part of post-genomics, proteomics has strengthened its position and also become the forefront of scientific research in this century. Magnetic nanomaterials in proteomics analysis is an interdisciplinary field combining magnetic nanomaterials science and proteomics. From the current research, magnetic nanomaterials have shown great potential in complex proteomics research.This book focuses on the application of magnetic nanomaterials in the forefront of proteomics research, and describes in details the synthetic methods, properties, principles and performance of magnetic nanomaterials in various branches of proteomics, which includes digestion studies, enrichment of low abundance peptides, as well as the analysis of phosphoprotein and glycoprotein. Past 10 years' research on magnetic materials in proteomics is integrated, and then the application of magnetic nanomaterials in proteomics analysis are stated systematically.This book can serve as reference book for teaching in the major of proteomics analysis, and also can be reference book for researchers who are studying materials for proteomics.
Novel Nanomaterials for Biomedical, Environmental and Energy Applications
Author: Xiaoru Wang
Publisher: Elsevier
ISBN: 012814498X
Category : Technology & Engineering
Languages : en
Pages : 496
Book Description
Novel Nanomaterials for Biomedical, Environmental, and Energy Applications is a comprehensive study on the cutting-edge progress in the synthesis and characterization of novel nanomaterials and their subsequent advances and uses in biomedical, environmental and energy applications. Covering novel concepts and key points of interest, this book explores the frontier applications of nanomaterials. Chapters discuss the overall progress of novel nanomaterial applications in the biomedical, environmental and energy fields, introduce the synthesis, characterization, properties and applications of novel nanomaterials, discuss biomedical applications, and cover the electrocatalytical and photothermal effects of novel nanomaterials for efficient energy applications. The book will be invaluable to academic researchers and biomedical clinicians working with nanomaterials. - Offers comprehensive details on novel and emerging nanomaterials - Presents a comprehensive view of new and emerging tactics for the synthesis of efficient nanomaterials - Describes and monitors the functions of applications of new and emerging nanomaterials in the biomedical, environmental and energy fields
Publisher: Elsevier
ISBN: 012814498X
Category : Technology & Engineering
Languages : en
Pages : 496
Book Description
Novel Nanomaterials for Biomedical, Environmental, and Energy Applications is a comprehensive study on the cutting-edge progress in the synthesis and characterization of novel nanomaterials and their subsequent advances and uses in biomedical, environmental and energy applications. Covering novel concepts and key points of interest, this book explores the frontier applications of nanomaterials. Chapters discuss the overall progress of novel nanomaterial applications in the biomedical, environmental and energy fields, introduce the synthesis, characterization, properties and applications of novel nanomaterials, discuss biomedical applications, and cover the electrocatalytical and photothermal effects of novel nanomaterials for efficient energy applications. The book will be invaluable to academic researchers and biomedical clinicians working with nanomaterials. - Offers comprehensive details on novel and emerging nanomaterials - Presents a comprehensive view of new and emerging tactics for the synthesis of efficient nanomaterials - Describes and monitors the functions of applications of new and emerging nanomaterials in the biomedical, environmental and energy fields
Applications of Nanomaterials in Proteomics
Author: Nianrong Sun
Publisher: Springer Nature
ISBN: 9811658161
Category : Science
Languages : en
Pages : 431
Book Description
This book provides a comprehensive and systematic overview of the latest advances in nanomaterials for proteomics, both theoretical and practical. Consisting of seven chapters, it first covers the synthesis methods, characterization, principles, and performance of functional nanomaterials in various branches of proteomics in detail. This is followed by the applications of nanomaterials for the separation and analysis of various proteins and peptides. Given its scope, the book appeals to a broad readership, including those active in proteomics and materials science; it can also serve as a reference book for students majoring in proteomics analysis.
Publisher: Springer Nature
ISBN: 9811658161
Category : Science
Languages : en
Pages : 431
Book Description
This book provides a comprehensive and systematic overview of the latest advances in nanomaterials for proteomics, both theoretical and practical. Consisting of seven chapters, it first covers the synthesis methods, characterization, principles, and performance of functional nanomaterials in various branches of proteomics in detail. This is followed by the applications of nanomaterials for the separation and analysis of various proteins and peptides. Given its scope, the book appeals to a broad readership, including those active in proteomics and materials science; it can also serve as a reference book for students majoring in proteomics analysis.
Analytical Sample Preparation With Nano- and Other High-Performance Materials
Author: Rafael Lucena
Publisher: Elsevier
ISBN: 0128221720
Category : Science
Languages : en
Pages : 573
Book Description
Analytical Sample Preparation With Nano- and Other High-Performance Materials covers advanced sample treatment techniques and the new materials that can be used to boost their performance. The evolution of sample treatment over the last two decades has resulted in the development of new techniques and application of new materials. This is a must-have resource for those studying advanced analytical techniques and the role of high-performance materials in analytical chemistry. The book explains the underlying principles needed to properly understand sample preparation, and also examines the latest materials - including nanomaterials - that result in greater sensitivity and specificity. The book begins with a section devoted to all the various sample preparation techniques and then continues with sections on high-performance sorbents and high-performance solvents. - Combines basic, fundamental principles and advanced concepts and applications for a comprehensive treatment of sample preparation with new materials - Defines nano- and other high-performance materials in this context, including carbon nanoparticles, inorganic nanoparticles, ionic liquids, supramolecular solvents, and more - Includes discussion of all the latest advancements and new findings in both techniques and materials used for proper sample preparation
Publisher: Elsevier
ISBN: 0128221720
Category : Science
Languages : en
Pages : 573
Book Description
Analytical Sample Preparation With Nano- and Other High-Performance Materials covers advanced sample treatment techniques and the new materials that can be used to boost their performance. The evolution of sample treatment over the last two decades has resulted in the development of new techniques and application of new materials. This is a must-have resource for those studying advanced analytical techniques and the role of high-performance materials in analytical chemistry. The book explains the underlying principles needed to properly understand sample preparation, and also examines the latest materials - including nanomaterials - that result in greater sensitivity and specificity. The book begins with a section devoted to all the various sample preparation techniques and then continues with sections on high-performance sorbents and high-performance solvents. - Combines basic, fundamental principles and advanced concepts and applications for a comprehensive treatment of sample preparation with new materials - Defines nano- and other high-performance materials in this context, including carbon nanoparticles, inorganic nanoparticles, ionic liquids, supramolecular solvents, and more - Includes discussion of all the latest advancements and new findings in both techniques and materials used for proper sample preparation
Magnetic Characterization Techniques for Nanomaterials
Author: Challa S.S.R. Kumar
Publisher: Springer
ISBN: 3662527804
Category : Technology & Engineering
Languages : en
Pages : 568
Book Description
Sixth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Magnetic Characterization Techniques for Nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.
Publisher: Springer
ISBN: 3662527804
Category : Technology & Engineering
Languages : en
Pages : 568
Book Description
Sixth volume of a 40 volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Magnetic Characterization Techniques for Nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.
Analytical Separation Science, 5 Volume Set
Author: Jared Anderson
Publisher: John Wiley & Sons
ISBN: 3527333746
Category : Science
Languages : en
Pages : 2148
Book Description
Endlich ein Forschungsleitfaden für Wissenschaftler des Fachgebiets, die neue Methoden entwickeln oder einsetzen. Dieses Handbuch umfasst fünf thematische Bände und bietet damit einen umfassenden Überblick über das Fachgebiet. Erläutert werden Grundlagen, die Methodenentwicklung und hochkarätige Anwendungen für alle wichtigen Analyseverfahren, darunter chromatische Verfahren, Techniken in den Bereichen Elektromigration und Membranen. Dieses Referenzwerk umfasst ein breites Spektrum und legt den Schwerpunkt auf Entwicklungen für die Zukunft. Damit ist es ein Muss für Forscher und eine wertvolle Wissensquelle für Studenten im Hauptstudium und Studienabsolventen.
Publisher: John Wiley & Sons
ISBN: 3527333746
Category : Science
Languages : en
Pages : 2148
Book Description
Endlich ein Forschungsleitfaden für Wissenschaftler des Fachgebiets, die neue Methoden entwickeln oder einsetzen. Dieses Handbuch umfasst fünf thematische Bände und bietet damit einen umfassenden Überblick über das Fachgebiet. Erläutert werden Grundlagen, die Methodenentwicklung und hochkarätige Anwendungen für alle wichtigen Analyseverfahren, darunter chromatische Verfahren, Techniken in den Bereichen Elektromigration und Membranen. Dieses Referenzwerk umfasst ein breites Spektrum und legt den Schwerpunkt auf Entwicklungen für die Zukunft. Damit ist es ein Muss für Forscher und eine wertvolle Wissensquelle für Studenten im Hauptstudium und Studienabsolventen.
Handbook of Smart Materials in Analytical Chemistry
Author: Miguel de la Guardia
Publisher: John Wiley & Sons
ISBN: 1119422590
Category : Science
Languages : en
Pages : 996
Book Description
A comprehensive guide to smart materials and how they are used in sample preparation, analytical processes, and applications This comprehensive, two-volume handbook provides detailed information on the present state of new materials tailored for selective sample preparation and the legal frame and environmental side effects of the use of smart materials for sample preparation in analytical chemistry, as well as their use in the analytical processes and applications. It covers both methodological and applied analytical aspects, relating to the development and application of new materials for solid-phase extraction (SPE) and solid-phase microextraction (SPME), their use in the different steps and techniques of the analytical process, and their application in specific fields such as water, food, air, pharmaceuticals, clinical sciences and forensics. Every chapter in Handbook of Smart Materials in Analytical Chemistry is written by experts in the field to provide a comprehensive picture of the present state of this key area of analytical sciences and to summarize current applications and research literature in a critical way. Volume 1 covers New Materials for Sample Preparation and Analysis. Volume 2 handles Analytical Processes and Applications. Focuses on the development and applications of smart materials in analytical chemistry Covers both, methodological and applied analytical aspects, for the development of new materials and their use in the different steps and techniques of the analytical process and their application in specific fields Features applications in key areas including water, air, environment, pharma, food, forensic, and clinical Presents the available tools for the use of new materials suitable to aid recognition process to the sample preparation and analysis A key resource for analytical chemists, applied laboratories, and instrument companies Handbook of Smart Materials in Analytical Chemistry, 2V Set is an excellent reference book for specialists and advanced students in the areas of analytical chemistry, including both research and application environments.
Publisher: John Wiley & Sons
ISBN: 1119422590
Category : Science
Languages : en
Pages : 996
Book Description
A comprehensive guide to smart materials and how they are used in sample preparation, analytical processes, and applications This comprehensive, two-volume handbook provides detailed information on the present state of new materials tailored for selective sample preparation and the legal frame and environmental side effects of the use of smart materials for sample preparation in analytical chemistry, as well as their use in the analytical processes and applications. It covers both methodological and applied analytical aspects, relating to the development and application of new materials for solid-phase extraction (SPE) and solid-phase microextraction (SPME), their use in the different steps and techniques of the analytical process, and their application in specific fields such as water, food, air, pharmaceuticals, clinical sciences and forensics. Every chapter in Handbook of Smart Materials in Analytical Chemistry is written by experts in the field to provide a comprehensive picture of the present state of this key area of analytical sciences and to summarize current applications and research literature in a critical way. Volume 1 covers New Materials for Sample Preparation and Analysis. Volume 2 handles Analytical Processes and Applications. Focuses on the development and applications of smart materials in analytical chemistry Covers both, methodological and applied analytical aspects, for the development of new materials and their use in the different steps and techniques of the analytical process and their application in specific fields Features applications in key areas including water, air, environment, pharma, food, forensic, and clinical Presents the available tools for the use of new materials suitable to aid recognition process to the sample preparation and analysis A key resource for analytical chemists, applied laboratories, and instrument companies Handbook of Smart Materials in Analytical Chemistry, 2V Set is an excellent reference book for specialists and advanced students in the areas of analytical chemistry, including both research and application environments.
Bio- and Bioinspired Nanomaterials
Author: Daniel Ruiz-Molina
Publisher: John Wiley & Sons
ISBN: 3527675841
Category : Technology & Engineering
Languages : en
Pages : 484
Book Description
A comprehensive overview of nanomaterials that are inspired by or targeted at biology, including some of the latest breakthrough research. Throughout, valuable contributions from top-level scientists illustrate how bionanomaterials could lead to novel devices or structures with unique properties. The first and second part cover the most relevant synthetic and bioinspired nanomaterials, including surfaces with extreme wettability properties, functional materials with improved adhesion or structural and functional systems based on the complex and hierarchical organization of natural composites. These lessons from nature are explored in the last section where bioinspired materials are proposed for biomedical applications, showing their potential for future applications in drug delivery, theragnosis, and regenerative medicine. A navigational guide aimed at advanced and specialist readers, while equally relevant for readers in research, academia or private companies focused on high added-value contributions. Young researchers will also find this an indispensable guide in choosing or continuing to work in this stimulating area, which involves a wide range of disciplines, including chemistry, physics, materials science and engineering, biology, and medicine.
Publisher: John Wiley & Sons
ISBN: 3527675841
Category : Technology & Engineering
Languages : en
Pages : 484
Book Description
A comprehensive overview of nanomaterials that are inspired by or targeted at biology, including some of the latest breakthrough research. Throughout, valuable contributions from top-level scientists illustrate how bionanomaterials could lead to novel devices or structures with unique properties. The first and second part cover the most relevant synthetic and bioinspired nanomaterials, including surfaces with extreme wettability properties, functional materials with improved adhesion or structural and functional systems based on the complex and hierarchical organization of natural composites. These lessons from nature are explored in the last section where bioinspired materials are proposed for biomedical applications, showing their potential for future applications in drug delivery, theragnosis, and regenerative medicine. A navigational guide aimed at advanced and specialist readers, while equally relevant for readers in research, academia or private companies focused on high added-value contributions. Young researchers will also find this an indispensable guide in choosing or continuing to work in this stimulating area, which involves a wide range of disciplines, including chemistry, physics, materials science and engineering, biology, and medicine.
Nanomaterials Recycling
Author: Mahendra Rai
Publisher: Elsevier
ISBN: 0323909833
Category : Technology & Engineering
Languages : en
Pages : 430
Book Description
Nanomaterial Recycling provides an update on the many benefits nanomaterials can provide on both environmental and economic issues. Sections cover the appropriate recycling strategies of nanowastes, nanowaste regulations (including nanowaste disposal and recycling standards), promising applications (reuses) of these recycled nanomaterials, and various methods used for the separation of nanoparticles, including (i) centrifugation, (ii)solvent evaporation, (iii) magnetic separation, (iv) using pH/thermal responsive materials, (v) molecular antisolvents, (vi) nanostructured colloidal solvents, and more. This book is an important reference source for materials scientists and engineers who are seeking to increase their understanding of nanomaterials, recycling processes and techniques. As nanomaterials can be recycled from both new/pure products (from nano manufacturing) and used products (nano waste: waste from nano integrated products), this book is a welcomed addition to many disciplines. - Provides information on how nanoscale recycling techniques can mitigate the most hazardous effects of nanomaterials - Explains the major recycling processes and techniques used for nanoscale materials - Assesses the major challenges of implementing nanoscale recycling approaches in a scalable and cost-effective manner
Publisher: Elsevier
ISBN: 0323909833
Category : Technology & Engineering
Languages : en
Pages : 430
Book Description
Nanomaterial Recycling provides an update on the many benefits nanomaterials can provide on both environmental and economic issues. Sections cover the appropriate recycling strategies of nanowastes, nanowaste regulations (including nanowaste disposal and recycling standards), promising applications (reuses) of these recycled nanomaterials, and various methods used for the separation of nanoparticles, including (i) centrifugation, (ii)solvent evaporation, (iii) magnetic separation, (iv) using pH/thermal responsive materials, (v) molecular antisolvents, (vi) nanostructured colloidal solvents, and more. This book is an important reference source for materials scientists and engineers who are seeking to increase their understanding of nanomaterials, recycling processes and techniques. As nanomaterials can be recycled from both new/pure products (from nano manufacturing) and used products (nano waste: waste from nano integrated products), this book is a welcomed addition to many disciplines. - Provides information on how nanoscale recycling techniques can mitigate the most hazardous effects of nanomaterials - Explains the major recycling processes and techniques used for nanoscale materials - Assesses the major challenges of implementing nanoscale recycling approaches in a scalable and cost-effective manner
Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine
Author: Paola Italiani
Publisher: Frontiers Media SA
ISBN: 2889453871
Category :
Languages : en
Pages : 177
Book Description
The immune system has the double role of maintaining tissue integrity and homeostasis and of protecting the organism from possible dangers, from invading pathogens to environmentally-borne dangerous chemicals. New chemicals recognisable by the immune system are engineered nanomaterials/ nanoparticles, new agents in our environment that are becoming common due to their presence in many products, from constructions and building material (e.g., solar cells, pigments and paints, tilesand masonry materials) to daily products (e.g., food packaging, cosmetics, and cigarettes). Human beings can be accidentally exposed to engineered nanomaterials when these are released from products containing them or during production in workplaces. Furthermore, intentional exposure occurs in medicine, as engineered nanoparticles are used as tools for improving delivery of drugs and vaccines, vaccine adjuvants and contrast agents in therapeutic, preventive and diagnostic strategies. Nanoparticles that come in contact with the immune system after unintentional exposure need to be eliminated from the organism as they represent a potential threat. In this case, however, due to their peculiar characteristics of size, shape, surface charge and persistence, nanoparticles may elicit undesirable reactions and have detrimental effects on the immune system, such as cytotoxicity, inflammation, anaphylaxis, immunosuppression. Conversely, nanomedicines need to escape immune recognition/elimination and must persist in the organism long enough for reaching their target and exerting their beneficial effects. Immune cells and molecules at the body surface (airway and digestive mucosae, skin) are the first that come in contact with nanomaterials upon accidental exposure, while immune effectors in blood are those that more easily come in contact with nanomedical products. Thus, evaluating the interaction of the immune system with nanoparticles/nanomaterials is a topic of key importance both in nanotoxicology and in nanomedicine. Immuno-nanosafety studies consider both accidental exposure to nanoparticles, which may occur by skin contact, ingestion or inhalation (at doses and with a frequency that are not known), and medical exposure, which takes place with a defined administration schedule (route, dose, frequency). Many studies focus on the interaction between the immune system and nanoparticles that, for medical purposes, have been specifically modified to stimulate immunity or to avoid immune recognition, as in the case of vaccine carriers/adjuvants or drug delivery systems, respectively. The aims of this Research Topic is to provide an overview of recent strategies: 1.for assessing the immunosafety of engineered nanomaterials/nanoparticles, in particular in terms of activation of inflammatory responses, such as complement activation and allergic reactions, based on the nanomaterial intrinsic characteristics and on the possible carry-over of bioactive contaminants such as LPS. Production of new nanoparticles taking into account their effects on immune responses, in order to avoid undesirable effects on one hand, and to design particles with desirable effects for medical applications on the other hand; 2.for designing more effective nanomedicines by either avoiding or exploiting their interaction with the immune systems, with particular focus on cancer diagnosis and therapy, and vaccination. This collection of articles gives a comprehensive view of the state-of-the-art of the interaction of nanoparticles with the immune system from the two perspectives of safety and medical use, and aims at providing immunologists with the relevant knowledge for designing improved strategies for immunologically safe nanomaterial applications.
Publisher: Frontiers Media SA
ISBN: 2889453871
Category :
Languages : en
Pages : 177
Book Description
The immune system has the double role of maintaining tissue integrity and homeostasis and of protecting the organism from possible dangers, from invading pathogens to environmentally-borne dangerous chemicals. New chemicals recognisable by the immune system are engineered nanomaterials/ nanoparticles, new agents in our environment that are becoming common due to their presence in many products, from constructions and building material (e.g., solar cells, pigments and paints, tilesand masonry materials) to daily products (e.g., food packaging, cosmetics, and cigarettes). Human beings can be accidentally exposed to engineered nanomaterials when these are released from products containing them or during production in workplaces. Furthermore, intentional exposure occurs in medicine, as engineered nanoparticles are used as tools for improving delivery of drugs and vaccines, vaccine adjuvants and contrast agents in therapeutic, preventive and diagnostic strategies. Nanoparticles that come in contact with the immune system after unintentional exposure need to be eliminated from the organism as they represent a potential threat. In this case, however, due to their peculiar characteristics of size, shape, surface charge and persistence, nanoparticles may elicit undesirable reactions and have detrimental effects on the immune system, such as cytotoxicity, inflammation, anaphylaxis, immunosuppression. Conversely, nanomedicines need to escape immune recognition/elimination and must persist in the organism long enough for reaching their target and exerting their beneficial effects. Immune cells and molecules at the body surface (airway and digestive mucosae, skin) are the first that come in contact with nanomaterials upon accidental exposure, while immune effectors in blood are those that more easily come in contact with nanomedical products. Thus, evaluating the interaction of the immune system with nanoparticles/nanomaterials is a topic of key importance both in nanotoxicology and in nanomedicine. Immuno-nanosafety studies consider both accidental exposure to nanoparticles, which may occur by skin contact, ingestion or inhalation (at doses and with a frequency that are not known), and medical exposure, which takes place with a defined administration schedule (route, dose, frequency). Many studies focus on the interaction between the immune system and nanoparticles that, for medical purposes, have been specifically modified to stimulate immunity or to avoid immune recognition, as in the case of vaccine carriers/adjuvants or drug delivery systems, respectively. The aims of this Research Topic is to provide an overview of recent strategies: 1.for assessing the immunosafety of engineered nanomaterials/nanoparticles, in particular in terms of activation of inflammatory responses, such as complement activation and allergic reactions, based on the nanomaterial intrinsic characteristics and on the possible carry-over of bioactive contaminants such as LPS. Production of new nanoparticles taking into account their effects on immune responses, in order to avoid undesirable effects on one hand, and to design particles with desirable effects for medical applications on the other hand; 2.for designing more effective nanomedicines by either avoiding or exploiting their interaction with the immune systems, with particular focus on cancer diagnosis and therapy, and vaccination. This collection of articles gives a comprehensive view of the state-of-the-art of the interaction of nanoparticles with the immune system from the two perspectives of safety and medical use, and aims at providing immunologists with the relevant knowledge for designing improved strategies for immunologically safe nanomaterial applications.