Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci PDF Download

Author: Stephen Nowicki
Publisher: Prometheus Books
ISBN: 1633880710
Category : Psychology
Languages : en
Pages : 274

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Book Description
How Much Do You Believe That What Happens to You Is the Result of Your Own Actions—or Do Circumstances Beyond Your Control Largely Determine Your Fate? Locus of Control (LOC) is a phrase used by psychologists to describe a widely effective way of assessing an individual’s potential for success—personal, social, and financial. LOC measures how much you believe what happens to you is the result of your own actions or, conversely, of forces and circumstances beyond your control. People who accept that they are largely in control of their lives tend to do better than those who feel that fate or external factors rule what they do, especially in novel and difficult situations. This book explains LOC research, until now mainly confined to academic circles, in terms easily understandable to the average person. The author, a clinical psychologist who has spent nearly five decades investigating and writing about LOC, helps the reader to explore his or her own locus of control and what those orientations might mean for how life is lived. He discusses the extensively documented relationship between LOC and academic achievement, personal and social adjustment, health, and financial success. Dr. Nowicki notes that there has been an increasing tendency among Americans to feel as though their lives are slipping out of their control, and he identifies ways to reverse this negative trend. He describes how the Locus of Control is learned and demonstrates ways in which it can be changed to yield higher levels of achievement, success, personal satisfaction, and better interactions with others.

Author: Victoria N. Alexander
Publisher:
ISBN: 9781689943659
Category :
Languages : en
Pages : 218

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Book Description
In this beautifully nuanced dark comedy, a 9/11 widow and her son, Hamlet, have retreated from Brooklyn to the idyllic rural countryside upstate, where for nearly eight years they have run a sustainable farm. Unfortunately, their outrageously obese neighbors, who prefer the starchy products of industrial agriculture, reject their elitist ways (recycling, eating healthy, reading).Hamlet, who is now eighteen, is beginning to suspect that something is rotten in the United States of America, when health, happiness, and freedom are traded for cheap Walmart goods, Paxil, endless war, standard curriculum, and environmental degradation. He becomes very depressed when, on the very day of the 8th anniversary of his father's death, his mother marries a horrid, boring bureaucrat named Claudius.Things get even more depressing for Hamlet when he learns from Horatio, a conspiracy theorist, that Claudius is a fraud. The deceptions, spying, and corruption will ultimately lead, as in Shakespeare's play, to tragedy.

Author:
Publisher: Academic Press
ISBN: 0128033304
Category : Medical
Languages : en
Pages : 476

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Book Description
Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes. - Focuses on the generation of an effective immune response to invading pathogens - Contains contributions from leading authorities - Informs and updates on all the latest developments in the field of immunology

Author: Nicola J. Camp
Publisher: Springer Science & Business Media
ISBN: 1592591760
Category : Medical
Languages : en
Pages : 362

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Book Description
In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.

Author: Igor M. Rouzine
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110608197
Category : Mathematics
Languages : en
Pages : 207

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Book Description
The book will benefit a reader with a background in physical sciences and applied mathematics interested in the mathematical models of genetic evolution. In the first chapter, we analyze several thought experiments based on a basic model of stochastic evolution of a single genomic site in the presence of the factors of random mutation, directional natural selection, and random genetic drift. In the second chapter, we present a more advanced theory for a large number of linked loci. In the third chapter, we include the effect of genetic recombination into account and find out the advantage of sexual reproduction for adaptation. These models are useful for the evolution of a broad range of asexual and sexual populations, including virus evolution in a host and a host population.

Author: Arthur Cayley
Publisher: University of Michigan Library
ISBN:
Category : Mathematics
Languages : en
Pages : 625

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Book Description
This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Author: Laurent Manivel
Publisher: American Mathematical Soc.
ISBN: 9780821821541
Category : Computers
Languages : en
Pages : 180

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Book Description
This text grew out of an advanced course taught by the author at the Fourier Institute (Grenoble, France). It serves as an introduction to the combinatorics of symmetric functions, more precisely to Schur and Schubert polynomials. Also studied is the geometry of Grassmannians, flag varieties, and especially, their Schubert varieties. This book examines profound connections that unite these two subjects. The book is divided into three chapters. The first is devoted to symmetricfunctions and especially to Schur polynomials. These are polynomials with positive integer coefficients in which each of the monomials correspond to a Young tableau with the property of being ``semistandard''. The second chapter is devoted to Schubert polynomials, which were discovered by A. Lascoux andM.-P. Schutzenberger who deeply probed their combinatorial properties. It is shown, for example, that these polynomials support the subtle connections between problems of enumeration of reduced decompositions of permutations and the Littlewood-Richardson rule, a particularly efficacious version of which may be derived from these connections. The final chapter is geometric. It is devoted to Schubert varieties, subvarieties of Grassmannians, and flag varieties defined by certain incidenceconditions with fixed subspaces. This volume makes accessible a number of results, creating a solid stepping stone for scaling more ambitious heights in the area. The author's intent was to remain elementary: The first two chapters require no prior knowledge, the third chapter uses some rudimentary notionsof topology and algebraic geometry. For this reason, a comprehensive appendix on the topology of algebraic varieties is provided. This book is the English translation of a text previously published in French.

Author: Webster Wells
Publisher:
ISBN:
Category : Geometry
Languages : en
Pages : 490

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Author: William Fulton
Publisher: Springer
ISBN: 3540698043
Category : Mathematics
Languages : en
Pages : 158

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Book Description
Schubert varieties and degeneracy loci have a long history in mathematics, starting from questions about loci of matrices with given ranks. These notes, from a summer school in Thurnau, aim to give an introduction to these topics, and to describe recent progress on these problems. There are interesting interactions with the algebra of symmetric functions and combinatorics, as well as the geometry of flag manifolds and intersection theory and algebraic geometry.

Author: Thomas E. Levy
Publisher: Springer
ISBN: 3319656937
Category : Social Science
Languages : en
Pages : 249

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Book Description
This volume asks how the current Information Technology Revolution influences archaeological interpretations of techno-social change. Does cyber-archaeology provide a way to breathe new life into grand narratives of technological revolution and culture change, or does it further challenge these high-level theoretical explanations? Do digital recording methods have the potential to create large, regional-scale databases to ease investigation of high-level theoretical issues, or have they simply exposed deeper issues of archaeological practice that prevent this? In short, this volume cuts beyond platitudes about the revolutionary potential of the Information Technology Revolution and instead critically engages both its possibilities and limitations. The contributions to this volume are drawn from long-term regional studies employing a cyber-archaeology framework, primarily in the southern Levant, a region with rich archaeological data sets spanning the Paleolithic to the present day. As such, contributors are uniquely placed to comment on the interface between digital methods and grand narratives of long-term techno-social change. Cyber-Archaeology and Grand Narratives provides a much-needed challenge to current approaches, and a first step toward integrating innovative digital methods with archaeological theory.