Morphological and Cellular Aspects of Tail and Limb Regeneration in Lizards PDF Download

Author: Lorenzo Alibardi
Publisher: Springer Science & Business Media
ISBN: 364203733X
Category : Medical
Languages : en
Pages : 117

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Book Description
The present review covers a very neglected field in regeneration studies, namely, tissue and organ regeneration in reptiles, especially represented by the lizard model of regeneration. The term “regeneration” is intended here as “the ability of an adult organism to recover damaged or completely lost body parts or organs.” The process of recovery is further termed “restitutive regeneration” when the lost part is reformed and capable of performing the complete or partial physiological activity performed by the original, lost body part. Lizards represent the only amniotes that at the same time show successful organ regeneration, in the tail, and organ failure, in the limb (Marcucci 1930a, b; Simpson 1961, 1970, 1983). This condition offers a unique opportunity to study at the same time mechanisms that in different regions of the same animal control the success or failure of regeneration. The lizard model is usually neglected in the literature despite the fact that the lizard is an amniote with a basic histological structure similar to that of mammals, and it is therefore a better model than the salamander (an a- mniote) model to investigate regeneration issues.

Author: David L. Stocum
Publisher: Academic Press
ISBN: 012384861X
Category : Technology & Engineering
Languages : en
Pages : 474

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Book Description
Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. - Highly Commended 2013 BMA Medical Book Award for Medicine - Includes coverage of skin, hair, teeth, cornea, and central neural tissues - Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems - Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals

Author: Ivo Hodek
Publisher: Springer Science & Business Media
ISBN: 9401713499
Category : Science
Languages : en
Pages : 475

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Book Description
Coccinellids have been very actively studied in the course of the twenty three years since "Biology of Coccinellidae" was published. The great amount of new, and often very important findings have made the previous book outdated and a new synthesis is needed. No other monograph of similar focus and extent has appeared. Iablokoff Khnzorian's "Les Coccinelles" (1982), limited to the tribus Coccinellini, and Gor don's "The Coccinellidae of America North of Mexico" (1985) both concentrate on taxonomy. Majerus' beautiful "Ladybirds" (1994) deal specifically with British coc cinellids and address chiefly amateur naturalists. The focus and the title of the recent book are slightly different from the 1973 vol ume. If a satisfactory comprehensive review of important new findings is attempted, the book would grow too much, due also to References and Indexes. To keep the vol ume at a tolerable extent, the section on larval identification of Palaearctic species has been omitted; not much could be added to the previous version of that part, any way. However, we have kept Kovar's chapter on morphology and anatomy, because of its relation to feeding and other ecological aspects. The chapter on phylogeny was updated also by him. Our Polish friend, Piotr Ceryngier, who has recently specialised in parasites, updated perfectly the parts on parasites and pathogens in Chapter 8. We would be glad if their contribution is quoted by their names. It seems to us that the remarks, contained in the reprinted preface to the previous volume, remain pertinent today.

Author: Robert Becker
Publisher: Harper Collins
ISBN: 0688069711
Category : Science
Languages : en
Pages : 370

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Book Description
The Body Electric tells the fascinating story of our bioelectric selves. Robert O. Becker, a pioneer in the filed of regeneration and its relationship to electrical currents in living things, challenges the established mechanistic understanding of the body. He found clues to the healing process in the long-discarded theory that electricity is vital to life. But as exciting as Becker's discoveries are, pointing to the day when human limbs, spinal cords, and organs may be regenerated after they have been damaged, equally fascinating is the story of Becker's struggle to do such original work. The Body Electric explores new pathways in our understanding of evolution, acupuncture, psychic phenomena, and healing.

Author: Lewis Wolpert
Publisher: Oxford University Press
ISBN: 0199601194
Category : Science
Languages : en
Pages : 153

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Book Description
"A concise account of what we know about development discusses the first vital steps of growth and explores one of the liveliest areas of scientific research."--P. [2] of cover.

Author: Brian K. Hall
Publisher: Academic Press
ISBN: 0124166857
Category : Science
Languages : en
Pages : 911

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Book Description
Bones and Cartilage provides the most in-depth review and synthesis assembled on the topic, across all vertebrates. It examines the function, development and evolution of bone and cartilage as tissues, organs and skeletal systems. It describes how bone and cartilage develop in embryos and are maintained in adults, how bone is repaired when we break a leg, or regenerates when a newt grows a new limb, or a lizard a new tail. The second edition of Bones and Cartilage includes the most recent knowledge of molecular, cellular, developmental and evolutionary processes, which are integrated to outline a unified discipline of developmental and evolutionary skeletal biology. Additionally, coverage includes how the molecular and cellular aspects of bones and cartilage differ in different skeletal systems and across species, along with the latest studies and hypotheses of relationships between skeletal cells and the most recent information on coupling between osteocytes and osteoclasts All chapters have been revised and updated to include the latest research. - Offers complete coverage of every aspect of bone and cartilage, with updated references and extensive illustrations - Integrates development and evolution of the skeleton, as well a synthesis of differentiation, growth and patterning - Treats all levels from molecular to clinical, embryos to evolution, and covers all vertebrates as well as invertebrate cartilages - Includes new chapters on evolutionary skeletal biology that highlight normal variation and variability, and variation outside the norm (neomorphs, atavisms) - Updates hypotheses on the origination of cartilage using new phylogenetic, cellular and genetic data - Covers stem cells in embryos and adults, including mesenchymal stem cells and their use in genetic engineering of cartilage, and the concept of the stem cell niche

Author: Richard J. Goss
Publisher: Elsevier
ISBN: 1483267652
Category : Science
Languages : en
Pages : 300

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Book Description
Principles of Regeneration focuses on the principles, methodologies, and changes involved in the process of regeneration. The book first underscores the nature of the nucleus in Acetabularia, enzyme effects, role of ribonucleic acid in morphogenesis, and functions of the stentor. The text then takes a look at the turnover in hydroids and flatworms and regeneration blastema. Discussions focus on regeneration in hydra, interstitial cells, colonial hydroids, neoblasts, and morphogenetic fields. The publication surveys segmental addition in annelids and molting, metamorphosis, and regeneration in arthropods. The termination of regeneration, importance of nerves, morphogenesis, histogenesis of the regenerate, and role of the nerves are discussed. The manuscript also examines regeneration in fishes, amphibian limb, horns and antlers, and heads and tails. The manuscript is a dependable source of data for students of developmental biology, anatomy, and evolution, as well as teachers and researchers in biology and medicine.

Author: Panagiotis A. Tsonis
Publisher: Cambridge University Press
ISBN: 9780521441490
Category : Medical
Languages : en
Pages : 264

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Book Description
This is the first book that analyses the mechanisms of limb regeneration by incorporating the information obtained from older experiments with the many new recent advances in molecular and cellular biology.

Author: Heinz Redl
Publisher: Springer
ISBN: 9783319088303
Category : Technology & Engineering
Languages : en
Pages : 0

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Book Description
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

Author: Bruce M. Carlson
Publisher: Elsevier
ISBN: 0080477968
Category : Science
Languages : en
Pages : 400

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Book Description
With the explosion of knowledge from molecular biology and the burgeoning interest in generating or regenerating tissues or organs through various bioengineering or stem cell approaches, many scientists and students have shown a renewed interest in the phenomenon of regeneration. Because relatively few have had the luxury of being able to approach the phenomenon of regeneration from a broad biological perspective, Dr. Carlson has produced a book that outlines the fundamental principles of regeneration biology. Subject matters focus principally on regeneration in vertebrate systems, but also invertebrate regeneration. In order to manipulate regenerative processes, it is important to understand the underlying principles of regeneration. Principles of Regnerative Biology is the key introductory reference for all developmental biologists, geneticists, and tissue and stem cell researchers. - Creates a general understanding of one of the most fascinating and complex phenomena in biology - Discusses the ability and diversity of regeneration in various organisms - Explains the history and origins of cells in regenerating systems - Includes information on stem cells and its important role in regeneration