Book Description
Au moment où l'on jugeait qu'elle commençait à tenir ses promesses, la thérapie génique a connu des ratés marquants. Aux Etats-Unis, chef de file des essais cliniques dans ce secteur de pointe, un jeune homme est mort des suites d'une thérapie génique à la fin des années 90. En toile de fond de ce drame : des allégations de laxisme et de conflit d'intérêts. En France, des cas de leucémie ont par la suite été rapportés chez des bébés-bulles soignés par la thérapie génique. Quelques années plus tôt, on les avait crus guéris. Ces mésaventures ont cruellement rappelé que la thérapie génique n'est pas une panacée et qu'elle demeure une procédure à l'efficacité incertaine. D'où l'importance, souligne Geneviève Cardinal, d'un encadrement conforme aux risques de cette nouvelle branche de la médecine. Or, à la suite d'une analyse de divers modèles normatifs en la matière, l'auteure témoigne des errances du gouvernement canadien d'une façon saisissante. L'étude comparative de Me Cardinal tombe à point nommé. En déficit de confiance, la technologie novatrice pourrait voir son avenir compromis. Chercheurs et décideurs doivent démontrer que l'évaluation et le contrôle des risques sont sans faille. C'est pourquoi ce livre, qui fait date au Canada, profitera aux scientifiques, éthiciens, juristes et politiciens. Il doit être lu attentivement. Les conclusions de son auteure susciteront le débat et, espérons-le, la réforme et l'innovation. La parution de ce premier liure donne un coup d'envoi à la toute nouvelle collection juridique intitulée " Droit, biotechnologie et société ". Cette collection a vu le jour grâce à un heureux partenariat regroupant lnstitut International de Recherche en Ethique Biomédicale (IIREB), la Chaire de recherche du Canada en droit et en médecine, le Centre de recherche en droit public (CRDP) et les Editions Thémis. Cette action commune porte aujourd'hui fruit. Nous souhaitons que l'analyse de sujets contemporains contribue à la réflexion collective nécessaire face au développement des biotechnologies.
Author: Andrea Boggio Publisher: Cambridge University Press ISBN: 9781108718448 Category : Law Languages : en Pages : 0
Book Description
The advent of the CRISPR/Cas9 class of genome editing tools is transforming not just science and medicine, but also law. When the genome of germline cells is modified, the modifications could be inherited, with far-reaching effects in time and scale. Legal systems are struggling with keeping up with the CRISPR revolution and both lawyers and scientists are often confused about existing regulations. This book contains an analysis of the national regulatory framework in eighteen selected countries. Written by national legal experts, it includes all major players in bioengineering, plus an analysis of the emerging international standards and a discussion of how international human rights standards should inform national and international regulatory frameworks. The authors propose a set of principles for the regulation of germline engineering, based on international human rights law, that can be the foundation for regulating heritable gene editing both at the level of countries as well as globally.
Author: Rodolphe Barrangou Publisher: Springer Science & Business Media ISBN: 364234657X Category : Science Languages : en Pages : 300
Book Description
CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.
Author: Kent Gustavson Publisher: World Bank Publications ISBN: 9780821346280 Category : Science Languages : en Pages : 316
Book Description
"The applied research indicates that, to improve awareness, park education programs should be targeted specifically to the user groups primarily through outreach programs. Further, the Park's management programs should be highlighted, particularly the beneficial, tangible products and services (benefits) the Park provides to each user group... The closer the tie between reef conditions and business earnings, the greater the users' support for reef conservation." Coral reefs are sometimes referred to as "canaries of the sea" because of their early warning ability to show near-shore oceanic stress. Because of their biological diversity, they are also called "rainforests of the sea." Coral reefs are vital to the well being of millions of people. Coral reef managers and government officials trying to save their valuable national resources have turned to research on coral reefs for help. The research presented in this publication merits a great deal of notice because the output is useful for decision support and training tools in integrated coastal zone management (ICZM). The work on cost-effectiveness analysis has developed integrated economic and ecological models, relying extensively on fuzzy logic procedures to model impacts and effects of interventions within the reef environment. By contrast, the marine system valuation work provides economic valuations of coral reefs, demonstrating the use of different modeling methods and treating key policy issues within this context. This publication will interest coastal zone experts and managers worldwide
Author: Patricia H. Miller Publisher: Macmillan Higher Education ISBN: 1319018734 Category : Psychology Languages : en Pages : 508
Book Description
Always reflective of the latest research and thinking in the field, Patricia Miller’s acclaimed text offers an ideal way to help students understand and distinguish the major theoretical schools of child development. This fully updated new edition includes a new focus on biological theories of development, and offers new instructor resource materials.
Author: Sibel Erduran Publisher: Springer Science & Business Media ISBN: 1402066708 Category : Science Languages : en Pages : 295
Book Description
Educational researchers are bound to see this as a timely work. It brings together the work of leading experts in argumentation in science education. It presents research combining theoretical and empirical perspectives relevant for secondary science classrooms. Since the 1990s, argumentation studies have increased at a rapid pace, from stray papers to a wealth of research exploring ever more sophisticated issues. It is this fact that makes this volume so crucial.
Author: Evelyn Fox KELLER Publisher: Harvard University Press ISBN: 0674039432 Category : Science Languages : en Pages : 194
Book Description
In a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology’s progress from gene to genome in one hundred years, The Century of the Gene also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene—word and object—as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.
Author: Samuel L. Odom Publisher: Guilford Press ISBN: 1606232487 Category : Psychology Languages : en Pages : 673
Book Description
This authoritative handbook reviews the breadth of current knowledge about developmental disabilities: neuroscientific and genetic foundations; the impact on health, learning, and behavior; and effective educational and clinical practices. Leading authorities analyze what works in intervening with diverse children and families, from infancy through the school years and the transition to adulthood. Chapters present established and emerging approaches to promoting communication and language abilities, academic skills, positive social relationships, and vocational and independent living skills. Current practices in positive behavior support are discussed, as are strategies for supporting family adaptation and resilience.
Author: Geneviève Cardinal
Author: Geneviève Cardinal
Author: Andrea Boggio
Author: Rodolphe Barrangou
Author: Kent Gustavson
Author: Patricia H. Miller
Author: Robert Plomin
Author: Sibel Erduran
Author: Evelyn Fox KELLER
Author: Samuel L. Odom