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Author: Richard D. Granstein Publisher: Springer Science & Business Media ISBN: 3540359893 Category : Medical Languages : en Pages : 248
Book Description
Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.
Author: Richard D. Granstein Publisher: Springer Science & Business Media ISBN: 3540359893 Category : Medical Languages : en Pages : 248
Book Description
Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.
Author: Vincenzo Guidetti Publisher: Springer ISBN: 3319547267 Category : Medical Languages : en Pages : 246
Book Description
This book aims to provide clinicians and other practitioners and professionals with up-to-date information on how to evaluate and manage headaches in children and adolescents, highlighting the most recent recommendations. Unlike in other books on the subject, detailed attention is devoted to the various comorbidities commonly associated with headache, including psychiatric comorbidities such as depression, anxiety, attention deficit hyperactivity disorder, and learning disabilities and medical conditions such as epilepsy, vascular disorders, brain tumors, atopic disease, and obesity. The intimate link between these conditions and headache is explained with a view to enabling the reader to recognize their presence and, on that basis, to institute the most effective pharmacological or non-pharmacological treatment strategy. Moreover, knowledge of the comorbidities associated with headache will help readers to understand more fully the causes of this serious disorder and also its consequences, e.g., for school performance, relationships, and daily activities. The authors are all international experts who care for children with headache or the other described disorders.
Author: Jason B. Wolf Publisher: Oxford University Press, USA ISBN: 9780195128062 Category : Science Languages : en Pages : 348
Book Description
Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.
Author: Beverley Greenwood-Van Meerveld Publisher: Springer ISBN: 3319563602 Category : Medical Languages : en Pages : 446
Book Description
This volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
Author: Marc G. Jeschke Publisher: Springer Nature ISBN: 3030391930 Category : Medical Languages : en Pages : 217
Book Description
The second edition of this practical guide offers a comprehensive summary of the most important and most immediate therapeutic approaches in the assessment and treatment of burn injuries. Taking into account age-specific needs in pediatric, adult, and elderly burn patients, several chapters on key issues – such as pre-hospital treatment, wound care and infection control, burn nursing, critical care, burn reconstructive surgery and rehabilitation for burn victims – have now been updated. In addition, the book has been supplemented with the latest information on fluid resuscitation, organ support for burn patients, necrotizing soft tissue infections, and TEN/SJS. Written in a concise manner, the updated edition of this book provides essential guidelines for optimal care to improve patient outcomes, and thus will be a valuable reference resource for physicians, surgeons, residents, nurses, and other burn care providers.
Author: Nikolaos Labrou Publisher: Springer Nature ISBN: 981137709X Category : Science Languages : en Pages : 388
Book Description
Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicity issues and various adverse events of the recombinant enzymes used for therapy are discussed. Section 4, provides discussion on the prospective and future developments of new therapeutic enzymes. This book is aimed at academics, researchers and students undertaking advanced undergraduate/postgraduate programs in the biopharmaceutical/biotechnology area who wish to gain a comprehensive understanding of enzyme-based therapeutic molecules.
Author: Derek S. Wheeler Publisher: Springer Science & Business Media ISBN: 1848009194 Category : Medical Languages : en Pages : 172
Book Description
The care of the critically ill or injured child begins with timely, prompt, and aggressive res- citation and stabilization. Ideally, stabilization should occur before the onset of organ failure in order to achieve the best possible outcomes. In the following pages, an international panel of experts provides an in-depth discussion of the early recognition, resuscitation, and stabilization of the critically ill or injured child. Once again, we would like to dedicate this textbook to our families and to the physicians and nurses who provide steadfast care every day in pediatric intensive care units across the globe. Derek S. Wheeler Hector R. Wong Thomas P. Shanley V Preface to Pediatric Critical Care Medicine: Basic Science and Clinical Evidence The ? eld of critical care medicine is growing at a tremendous pace, and tremendous advances in the understanding of critical illness have been realized in the last decade. My family has directly bene? ted from some of the technological and scienti? c advances made in the care of critically ill children. My son Ryan was born during my third year of medical school. By some peculiar happenstance, I was nearing completion of a 4-week rotation in the newborn intensive care unit (NICU). The head of the pediatrics clerkship was kind enough to let me have a few days off around the time of the delivery—my wife, Cathy, was 2 weeks past her due date and had been scheduled for elective induction.
Author: Arkadi Vigalok Publisher: Springer ISBN: 3642120733 Category : Science Languages : en Pages : 198
Book Description
Contents: Kilian Muñiz: Transition Metal Catalyzed Electrophilic Halogenation of C-H bonds in alpha-Position to Carbonyl Groups; Arkadi Vigalok * and Ariela W Kaspi: Late Transition Metal-Mediated Formation of Carbon-Halogen Bonds; Paul Bichler and Jennifer A. Love*: Organometallic Approaches to Carbon-Sulfur Bond Formation; David S. Glueck: Recent Advances in Metal-Catalyzed C-P Bond Formation; Andrei N. Vedernikov: C-O Reductive Elimination from High Valent Pt and Pd Centers; Lukas Hintermann: Recent Developments in Metal-Catalyzed Additions of Oxygen Nucleophiles to Alkenes and Alkynes; Moris S. Eisen: Catalytic C-N, C-O and C-S bond formation promoted by organoactinide complexes.
Author: Mauro Varotto Publisher: Springer ISBN: 3319968157 Category : Technology & Engineering Languages : en Pages : 357
Book Description
This volume collects the best scientific contribution presented in the 3rd World Conference on Terraced Landscapes held in Italy from 6th to 15th October 2016, offering a deep and multifaceted insight into the remarkable heritage of terraced landscapes in Italy, in Europe and in the World (America, Asia, Australia). It consists of 2 parts: a geographical overview on some of the most important terraced systems in the world (1st part), and a multidisciplinary approach that aims to promote a multifunctional vision of terraces, underlining how these landscapes meet different needs: cultural and historical values, environmental and hydrogeological functions, quality and variety of food, community empowerment and sustainable development (2nd part). The volume offers a great overview on strengths, weaknesses, functions and strategies for terraced landscapes all over the world, summarizing in a final manifest the guidelines to provide a future for these landscapes as natural and cultural heritage.
Author: Richard D. Granstein
Author: Richard D. Granstein
Author: Vincenzo Guidetti
Author: Jason B. Wolf
Author: Beverley Greenwood-Van Meerveld
Author: Marc G. Jeschke
Author: Robert Burns
Author: Nikolaos Labrou
Author: Derek S. Wheeler
Author: Arkadi Vigalok
Author: Mauro Varotto