The Neuropathology of Dementia PDF Download

Author: Margaret M. Esiri
Publisher: Cambridge University Press
ISBN: 9780521819152
Category : Medical
Languages : en
Pages : 600

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Book Description
Completely rewritten and updated, this new edition is almost twice the size of its predecessor. Illustrated in colour throughout, and with contributions from the world's leading authorities, it is the definitive reference on the neuropathology of dementia. It gives practical guidance to pathologists, describes the contribution of neuroimaging to diagnosis, and surveys the clinical features of dementia. New material includes: Three entirely new chapters on neuroimaging, molecular diagnostics, and transgenic models. Two chapters on tauopathies under new authorship. A chapter under new authorship on synucleinopathies, which includes multiple system atrophy.

Author: Francoise Gray
Publisher: Oxford University Press
ISBN: 0199330484
Category : Medical
Languages : en
Pages : 421

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Book Description
Now in its 5th edition, Escourolle & Poirier Manual of Basic Neuropathology continues the tradition of being one of the most respected texts in neuropathology by providing an introduction to the various diseases of the nervous system and their underlying pathology. This thorough, yet concise manual covers the full spectrum of the various categories of neurologic disease, including neoplasia, trauma, vascular disease, and infection, with separate chapters on prion diseases, multiple sclerosis, degenerative disorders, acquired metabolic diseases, hereditary metabolic diseases, congenital malformations, perinatal diseases, skeletal muscle, peripheral nerve, and the pituitary gland. To accurately guide the clinician, the most current techniques in neuropathology are covered in their own chapter at the end of the book. Richly illustrated throughout, with over 700 images of various neuropathogical diagnoses such as tumor, stroke, infection, degeneration, and malformation among others, this new edition of the classic monograph is an easy-to-use manual for any student, researcher, or practitioner seeking basic information on neuropathology. Used for decades in all fields related to the nervous system-including neurology, neurosurgery, psychiatry, neuroradiology, neuroendocrinology, neuropathology, pathology, and neuroscience- Escourolle & Poirier Manual of Basic Neuropathology is regarded at the 'bible' of neuropathology. This new version has been completely rewritten and expanded to include important updates in genetics and molecular biology, reflective of the important neuropathological discoveries in those fields over the past decade.This book is a practical diagnostic tool and necessary reading for anyone encountering pathological conditions of the nervous system.

Author: Udo Rüb
Publisher: Springer
ISBN: 331919285X
Category : Medical
Languages : en
Pages : 154

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Book Description
This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.

Author: Manfred Oehmichen
Publisher: Springer Science & Business Media
ISBN: 9783540235002
Category : Law
Languages : en
Pages : 696

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Book Description
The present volume deals with specific aspects of neuropathology for forensic and clinical neuropathologists, with particular emphasis on their relevance to everyday practice. Each chapter includes an overview of the literature as well as specific references and features a wealth of figures, graphs, and tables.

Author: Juan M Bilbao
Publisher: Springer
ISBN: 3319073117
Category : Medical
Languages : en
Pages : 499

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Book Description
Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.

Author: Kathreena M. Kurian
Publisher: Cambridge University Press
ISBN: 1107038162
Category : Medical
Languages : en
Pages : 243

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Book Description
Unparalleled access to the entire central nervous system with over four hundred gross neuropathology images from adult and paediatric post-mortem tissues.

Author: Gabor G. Kovacs
Publisher: Cambridge University Press
ISBN: 1316337650
Category : Medical
Languages : en
Pages : 320

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Book Description
This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases.

Author: James S. Nelson
Publisher: Oxford University Press, USA
ISBN: 9780195125894
Category : Medical
Languages : en
Pages : 624

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Book Description
From reviews of the First Edition: "Being a concise introduction to the principles of neruopathology is a goal this book accomplishes admirably." Annals of Neurology; "unquestionably valuable as a reference text" Arch Path Lab Med; "a fine treatise which truly reflects the current knowledge of the discipline with a strong emphasis on morphologic aspects" Brain Pathology; "an excellent current reference work on neuropathology for practitioners in the various clinical and basic neurosciences" Journal of Neuropathology and Experimental Neurology.

Author: National Research Council
Publisher: National Academies Press
ISBN: 0309288037
Category : Medical
Languages : en
Pages : 215

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Book Description
In the past decade, few subjects at the intersection of medicine and sports have generated as much public interest as sports-related concussions - especially among youth. Despite growing awareness of sports-related concussions and campaigns to educate athletes, coaches, physicians, and parents of young athletes about concussion recognition and management, confusion and controversy persist in many areas. Currently, diagnosis is based primarily on the symptoms reported by the individual rather than on objective diagnostic markers, and there is little empirical evidence for the optimal degree and duration of physical rest needed to promote recovery or the best timing and approach for returning to full physical activity. Sports-Related Concussions in Youth: Improving the Science, Changing the Culture reviews the science of sports-related concussions in youth from elementary school through young adulthood, as well as in military personnel and their dependents. This report recommends actions that can be taken by a range of audiences - including research funding agencies, legislatures, state and school superintendents and athletic directors, military organizations, and equipment manufacturers, as well as youth who participate in sports and their parents - to improve what is known about concussions and to reduce their occurrence. Sports-Related Concussions in Youth finds that while some studies provide useful information, much remains unknown about the extent of concussions in youth; how to diagnose, manage, and prevent concussions; and the short- and long-term consequences of concussions as well as repetitive head impacts that do not result in concussion symptoms. The culture of sports negatively influences athletes' self-reporting of concussion symptoms and their adherence to return-to-play guidance. Athletes, their teammates, and, in some cases, coaches and parents may not fully appreciate the health threats posed by concussions. Similarly, military recruits are immersed in a culture that includes devotion to duty and service before self, and the critical nature of concussions may often go unheeded. According to Sports-Related Concussions in Youth, if the youth sports community can adopt the belief that concussions are serious injuries and emphasize care for players with concussions until they are fully recovered, then the culture in which these athletes perform and compete will become much safer. Improving understanding of the extent, causes, effects, and prevention of sports-related concussions is vitally important for the health and well-being of youth athletes. The findings and recommendations in this report set a direction for research to reach this goal.

Author: Jacques Philippon
Publisher: Oxford University Press
ISBN: 0195369750
Category : Biography & Autobiography
Languages : en
Pages : 470

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Book Description
"In this volume, two French physicians, Jacques Philippon and Jacques Poirier, analyze Joseph Babinski's great scientific achievements, explore his unique family history, and publish for the first time a complete bibliography of his publications." "This book chronicles his family's emigration from Poland to France, his tutelage and early career under great teachers such as Alfred Vulpian, Victor Cornil, and Jean-Martin Charcot at the Hopital de la Salpetriere in Paris, his methods and observations during his 17 years as department head at La Pitie, as well as the close and unique relationship with his brother Henri. Finally, Babinski's life and times can be accessed in one book."--BOOK JACKET.