Author: M. Extermann
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318023078
Category : Medical
Languages : en
Pages : 179

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Book Description
Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty.This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.

Author: Felipe Sierra
Publisher: Springer
ISBN: 3319232460
Category : Medical
Languages : en
Pages : 637

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Book Description
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.

Author: Danan Gu
Publisher: Springer
ISBN: 9783030220082
Category : Family & Relationships
Languages : en
Pages : 5507

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Book Description
This eight-volume encyclopedia brings together a comprehensive collection of work highlighting established research and emerging science in all relevant disciplines in gerontology and population aging. It covers the breadth of the field, gives readers access to all major sub-fields, and illustrates their interconnectedness with other disciplines. With more than 1300 cross-disciplinary contributors—including anthropologists, biologists, economists, psychiatrists, public policy experts, sociologists, and others—the encyclopedia delves deep into key areas of gerontology and population aging such as ageism, biodemography, disablement, longevity, long-term care, and much more. Paying careful attention to empirical research and literature from around the globe, the encyclopedia is of interest to a wide audience that includes researchers, teachers and students, policy makers, (non)governmental agencies, public health practitioners, business planners, and many other individuals and organizations.

Author: Ian Stuart-Hamilton
Publisher: Cambridge University Press
ISBN: 1139500171
Category : Psychology
Languages : en
Pages : 459

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Book Description
With the world's population getting increasingly older, there has never been a more pressing need for the study of old age and ageing. An Introduction to Gerontology provides a wide-ranging introduction to this important topic. By assuming no prior expert knowledge and avoiding jargon, this book will guide students through all the main subjects in gerontology, covering both traditional areas, such as biological and social ageing, and more contemporary areas, such as technology, the arts and sexuality. An Introduction to Gerontology is written by a team of international authors with multidisciplinary backgrounds who draw evidence from a variety of different perspectives and traditions.

Author:
Publisher: Academic Press
ISBN: 0128160764
Category : Medical
Languages : en
Pages : 1656

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Book Description
Encyclopedia of Biomedical Gerontology, Three Volume Set presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention. Provides a ‘one-stop’ resource to information written by world-leading scholars in the field of biomedical gerontology Fills a critical gap of information in a field that has seen significant progress in the last 10 years

Author: Christian E. Waugh
Publisher: Springer Nature
ISBN: 3030829650
Category : Psychology
Languages : en
Pages : 343

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Book Description
This book features cutting edge research on the theory and measurement of affect dynamics from the leading experts in this emerging field. Authors will discuss how affect dynamics are instantiated across neural, psychological and behavioral levels of processing and provide state of the art analytical and computational techniques for assessing temporal changes in affective experiences. In the section on Within-episode Affect Dynamics, the authors discuss how single emotional episodes may unfold including the duration of affective responses, the dynamics of regulating those affective responses and how these are instantiated in the brain. In the section on Between-episode Affect Dynamics, the authors discuss how emotions and moods at one point in time may influence subsequent emotions and moods, and the importance of the time-scales on which we assess these dynamics. In the section on Between-person Dynamics the authors propose that interactions and relationships with others form much of the basis of our affect dynamics. Lastly, in the section on Computational Models of Affect, authors provide state of the art analytical techniques for assessing and modeling temporal changes in affective experiences. Affect Dynamics will serve as a reference for both seasoned and beginning affective science researchers to explore affect changes across time, how these affect dynamics occur, and the causal antecedents of these dynamics.

Author: Mark P. Mattson
Publisher: Elsevier
ISBN: 9780444518767
Category : Medical
Languages : en
Pages : 212

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Book Description
Sleep and Aging provides a unique and timely collection of review articles that cover the gamut of basic and clinical aspects of sleep and the abnormalities in sleep associated with aging and neurological disorders that occur during aging. From the evolutionary basis of sleep and its normal functions in processes such as learning and memory, to considerations of the roles of sleep abnormalities in neurological disorders such as depression, Alzheimer's and Parkinson's diseases, the chapters are written by experts in the field. Several chapters focus on signalling pathways involved in sleep regulation and abnormalities in sleep, including those activated by serotonin and BDNF. Basic and clinical research on insomnia, sleep apnea and other disorders of sleep, are covered thus providing students and scientists at all levels with a valuable source of information to advance their understanding of this important topic in aging, biology and medicine. The circuits in the brain involved in sleep regulation, their neurochemistry, how they are altered in disorders of sleep and current clinical treatments of various sleep disorders are reviewed. The important role of sleep disturbances in neurodegenerative disorders is described and research in this particular area is leading to a better understanding of the relationships between synaptic plasticity, neuronal degeneration and the clinical manifestations of disorders such as Alzheimer's disease, Parkinson's disease and depression. This book is a must for scientists, as well as non-scientists, who are interested in the neurobiology of aging, sleep and neurodegenerative disorders.

Author: J Dianne Garner
Publisher: Routledge
ISBN: 1317826493
Category : Psychology
Languages : en
Pages : 220

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Book Description
Explore feminist ideals and advocacy for aging women in health care, home life, work, and retirement! Fundamentals of Feminist Gerontology strives to increase women’s self-esteem and their overall quality of life by encouraging education and by putting a stop to age, sex, and race discrimination. As a student or professional in psychology, social work, or gerontology, you will learn about feminist conceptions of retirement, economic issues, psychological issues, and social issues and will explore studies on old age discrimination and devaluation and sexism toward women in Western societies to gain an understanding of the experiences of these women. This book also shows how some women are experiencing empowerment through alternative health care, such as mind-body therapies, homeopathy, aromatherapy, and herbal medicine and examines older women in the family context. Fundamentals of Feminist Gerontology will provide you with the tools to offer effective therapy to women to help them improve their own lives. For a complete list of contents, please visit our Web site at www.haworthpressinc.com. Using feminist practice approaches, Fundamentals of Feminist Gerontology gives you real-life situations and examples that will raise awareness of the issues that rob older women of the quality of life they deserve. Some of the vital issues and theories you will read about in Fundamentals of Feminist Gerontology include: women regaining control over their health care retirement and the economic issues that older women face when they retire the role of children and grandchildren in the older woman’s life unpaid work after retirement in the home and as a care provider older women battling domestic violence financial and psychological issues of widowhood special concerns of minority women and lesbians as they grow older Fundamentals of Feminist Gerontology presents new feminist knowledge and strategies to assist aging women in fully developing, enhancing, and enjoying their later years. You will discover a rich variety of theories and frameworks from a multitude of intellectual paradigms and political positions to enhance your professional practice with older women.

Author: Giacinto Libertini
Publisher: Springer Nature
ISBN: 3030737748
Category : Social Science
Languages : en
Pages : 413

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Book Description
This book provides concrete scientific basis that we can conceive the possibility of modifying or even completely canceling aging process, despite the fact that aging is commonly regarded as the result of the overall effects of many uncontrollable degenerative phenomena. The authors illustrate in detail the mechanisms by which cells and the whole organism age. Actions by which it is possible, or will be possible within a limited time, to operate for modifying aging are also debated. The discussion is conducted within the frame and the concepts of evolutionary medicine, which is also indispensable for distinguishing between the manifestations of aging and: (i) diseases that worsen with age, and (ii) acceleration of normal aging rates, caused by unhealthy lifestyle habits and other avoidable factors. The book also discusses the impact of aging on overall mortality and the strange situation that, according to official statistics, aging does not exist as cause of death. This book is a turning point between a gerontology and geriatrics conceived as the study and vain treatment of an incurable condition and one in which these disciplines examine the how and why of a physiological phenomenon that can be modified up to a possible total control. This means transforming the medical prevention and treatment of physiological aging from the greatest failure to the greatest success of medicine.

Author: Lewis R. Aiken
Publisher: SAGE
ISBN: 9780803954458
Category : Medical
Languages : en
Pages : 488

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Book Description
This study identifies and reviews "what is known about aging and older adulthood and the methods by which such information and the resulting practical guidelines for dealing with the problems and possibilities of this time of life have been and continue to be obtained."--From Preface.