Isozymes: Biochemical and Genetic Studies PDF Download

Author: Peggy Clark
Publisher: Ardent Media
ISBN: 9780842271264
Category : Science
Languages : en
Pages : 298

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Author: Christopher Rider
Publisher: Springer
ISBN: 9780412156403
Category : Science
Languages : en
Pages : 80

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Book Description
Isoenzymes were 'discovered' 20 years ago and were at first regarded as interesting but rare occurrences. Since then a wealth of information on enzyme heterogeneity has accrued and it now seems likely that at least half of all enzymes exist as isoenzymes. This is important in many areas of biological and medical science. Thus isoenzyme studies have provided the main experimental substance for the neutral drift controversy in genetics and evolution; they have greatly extended our understanding of metabolic regulation not only in animals but also in bacteria and plants; their existence has made available a multitude of highly sensitive markers for the study of differentiation and development, as well as providing indices of aberrant gene expression in carcinogenesis and other pathological processes. Iso enzymes are also being used increasingly in diagnostic clinical bio chemistry. It is surprising that this phenomenon which affects such a high pro portion of enzymes and is clearly important in biochemistry should receive such scant attention in the standard textbooks of that subject, the formal treatment of isoenzymology in these rarely exceeding one or two pages. This may be because the 'pure biochemist' has tended to regard variation in enzyme properties between tissues more as an unwanted complication than as a potential source of insight into diversity of biological function.

Author: Douglas E. Soltis
Publisher: Springer Science & Business Media
ISBN: 9400918402
Category : Science
Languages : en
Pages : 273

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Author: Robert E. Gaensslen
Publisher:
ISBN:
Category : Blood group antigens
Languages : en
Pages : 730

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Author: John W. Pelley, PhD
Publisher: Elsevier Health Sciences
ISBN: 0323074464
Category : Medical
Languages : en
Pages : 254

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Book Description
Effectively merge basic science and clinical skills with Elsevier's Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com - included with your purchase - allows you to conveniently access the book's complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with both case-based, andUSMLE-style questions that provide effective chapter review and quick practice for your exams. Access the full contents online at www.studentconsult.com where you'll find the complete text and illustrations, "Integration Links" to bonus content in other Student Consult titles, an interactive community center with a wealth of additional resources, and much more! Grasp and retain vital concepts more easily thanks to a color-coded format, succinct,text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material. Great for visual learners!

Author: George Fink
Publisher: Academic Press
ISBN: 0123750970
Category : Medical
Languages : en
Pages : 895

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Book Description
Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles.

Author: William F. Martin
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110612410
Category : Science
Languages : en
Pages : 269

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Mitochondria are sometimes called the powerhouses of eukaryotic cells, because mitochondria are the site of ATP synthesis in the cell. ATP is the universal energy currency, it provides the power that runs all other life processes. Humans need oxygen to survive because of ATP synthesis in mitochondria. The sugars from our diet are converted to carbon dioxide in mitochondria in a process that requires oxygen. Just like a fire needs oxygen to burn, our mitochondria need oxygen to make ATP. From textbooks and popular literature one can easily get the impression that all mitochondria require oxygen. But that is not the case. There are many groups of organismsm known that make ATP in mitochondria without the help of oxygen. They have preserved biochemical relicts from the early evolution of eukaryotic cells, which took place during times in Earth history when there was hardly any oxygen avaiable, certainly not enough to breathe. How the anaerobic forms of mitochondria work, in which organisms they occur, and how the eukaryotic anaerobes that possess them fit into the larger picture of rising atmospheric oxygen during Earth history are the topic of this book.

Author: W.R. Chegwidden
Publisher: Birkhäuser
ISBN: 303488446X
Category : Science
Languages : en
Pages : 614

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Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), has found favour as a model for the study of evolution of gene families and for site-directed mutagenesis in structure/function relationships, for protein folding and for transgenic and gene target studies. Since the early use of CA inhibitors as diuretics and in treating congestive heart failure, the enzyme has been target of considerable clinical attention. Much of this is now focused on endeavours to produce a new generation of such drugs for the effective treatment of glaucoma and other potential applications. Recent data, suggesting links between CA and various disease processes, including cancer, have stimulated further...

Author: Peter R. Shewry
Publisher: Springer Science & Business Media
ISBN: 9401144311
Category : Science
Languages : en
Pages : 892

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Book Description
Seeds provide more than half of the world's intake of dietary protein and energy and thus are of immense economic, cultural and nutritional importance. Proteins can account for up to 40% of the dry weight of various types of seeds, thereby making a large contribution to the nutritional quality and processing properties of seeds. It is, therefore, not surprising that seed proteins were among the first plant components to be systematically studied, some 250 years ago, and have been a major focus of research over the past 100 years. The properties and behaviour of seed proteins pervade modem life in numerous ways. For example, legume and cereal proteins are used'in the production of a wide range of meat-free foods; the process of bread-making is dep~ndent on the physical chemical properties of wheat seed proteins; and in developed, as well as developing, countries, nutritional deficiencies among vegetarian diets are avoided through balancing legume and cereal seeds as sources of dietary proteins. Understanding seed proteins, in order to improve their composition and properties and to increase their concentrations, will thus continue to be an important research objective for the future. The present volume represents the culmination of a long-discussed plan of the editors, to bring together the best international authorities in order to compile a definitive monograph on biological, biochemical, molecular and genetic aspects of seed proteins.

Author:
Publisher: Elsevier
ISBN: 0444600388
Category : Technology & Engineering
Languages : en
Pages : 527

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Book Description
Developments in Plant Genetics and Breeding, 1A: Isozymes in Plant Genetics and Breeding, Part A focuses on the advancements in the processes, methodologies, and approaches involved in the study of isozymes, including its role in plant genetics and breeding. The selection first elaborates on the historical perspectives of plant isozymes, plant genetics, and isozyme systems to study gene regulation during development. Discussions focus on the use of isozyme and similar comparisons to study differential gene regulation, gene preservation, dissemination of cultivars, propagation of cultivars and breeding lines, and studies on the effect of viral infection and hormones on isozyme expression. The text then examines allozymes in gene dosage studies, gene mapping, and plastid isozymes. The manuscript takes a look at the genetics of mitochondrial isozymes, evolution of plant isozymes, and detection of somatic variation. Topics include evolution of isozymes in plants, generation of isozymes, glutamate dehydrogenase, glutamate-oxaloacetate transaminase, and malate dehydrogenase. The text also ponders on enzyme activity staining, isozymic variation and plant breeders' rights, genetic purity of commercial seed lots, and use of isozymes in plant disease research. The selection is a valuable reference for researchers interested in the role of isozymes in plant genetics and breeding.