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Author: J.P. Andersen Publisher: Elsevier ISBN: 0080877079 Category : Science Languages : en Pages : 273
Book Description
Both eukaryotic and prokaryotic cells depend strongly on the function of ion pumps present in their membranes. The term ion pump, synonymous with active ion-transport system, refers to a membrane-associated protein that translocates ions uphill against an electrochemical potential gradient. Primary ion pumps utilize energy derived from chemical reactions or from the absorption of light, while secondary ion pumps derive the energy for uphill movement of one ionic species from the downhill movement of another species. In the present volume, various aspects of ion pump structure, mechanism, and regulation are treated using mostly the ion-transporting ATPases as examples. One chapter has been devoted to a secondary ion pump, the Na+-Ca2+ exchanger, not only because of the vital role played by this transport system in regulation of cardiac contractility, but also because it exemplifies the interesting mechanistic and structural similarities between primary and secondary pumps.
Author: J.P. Andersen Publisher: Elsevier ISBN: 0080877079 Category : Science Languages : en Pages : 273
Book Description
Both eukaryotic and prokaryotic cells depend strongly on the function of ion pumps present in their membranes. The term ion pump, synonymous with active ion-transport system, refers to a membrane-associated protein that translocates ions uphill against an electrochemical potential gradient. Primary ion pumps utilize energy derived from chemical reactions or from the absorption of light, while secondary ion pumps derive the energy for uphill movement of one ionic species from the downhill movement of another species. In the present volume, various aspects of ion pump structure, mechanism, and regulation are treated using mostly the ion-transporting ATPases as examples. One chapter has been devoted to a secondary ion pump, the Na+-Ca2+ exchanger, not only because of the vital role played by this transport system in regulation of cardiac contractility, but also because it exemplifies the interesting mechanistic and structural similarities between primary and secondary pumps.
Author: Armin Kargol Publisher: Morgan & Claypool Publishers ISBN: 1643274104 Category : Science Languages : en Pages : 117
Book Description
All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.
Author: Pradip K Datta Publisher: JP Medical Ltd ISBN: 1909836672 Category : Medical Languages : en Pages : 488
Book Description
MRCS Part A: 550 SBAs and EMQs, Second Edition continues the tradition of the best-selling first edition by offering a wealth of practice questions covering applied basic sciences and principles of surgery for candidates preparing for the MRCS Part A written exam. With 40% new content, including the addition of trauma and orthopaedic questions to provide complete coverage of surgical specialties, this book remains an essential revision tool designed to maximise chances of exam success. Key points 550 SBAs and theme-based EMQs test knowledge of applied basic sciences and general surgical principles, respectively, reflecting the formats encountered in the exam Chapters organised by anatomy, physiology, pathology, principles of surgery and general surgery, to help you focus on areas of weakness Provides in-depth answers, with illustrations, to help consolidate knowledge and understand key concepts Gives practical advice on how to approach revision and useful tips to improve exam technique
Author: Edward Bittar Publisher: Elsevier ISBN: 0080528732 Category : Science Languages : en Pages : 361
Book Description
The first section of this volume consists of five chapters to the nature of membrane transport systems. A chapter on secondary active glucose transport has been omitted because this topic is slated to appear in the Nephrobiology module. Chapter 6 deals with oxidase control of plasma membrane proton transport, while chapter 7 addresses the question of how cell volume is regulated. Although we chose not to have a separate chapter covering additional co-transport systems namely, Na+ -K+ -2CI-, KCI, -HCO-3, as well as CI- -HCO-3 exchange and K+ and CI- movements through channels, the role of each in cell volume regulation is emphasized in Chapter 7. Instead of devoting an entire section to the thermodynamics of metabolism, we thought it desirable to have the subjects of medical imaging and NMR of cell metabolism discussed in some detail in two chapters. These are followed by a chapter on the thermodynamic instrument - the calorimeter. Calrimetry allows the measurement of net changes of heat in cells, tissues, organs and whole body. As will be recognized, heat dissipation does not arise only from chemical reactions but also from interactions between macromolecules and conformational changes in protein complexes and mass Ca2+ movement such as that occurring in contracting skeletal muscle. The last chapter provides an account of equilibrium and non-equilibrium thermodynamics and the enthalpy balance method. It reveals that calometric measurements are useful in studies of clinical and toxicological problems.
Author: Pradip K Datta Publisher: JP Medical Ltd ISBN: 190781633X Category : Medical Languages : en Pages : 464
Book Description
Featuring a wealth of practice questions, MRCS Part A: 500 SBAs and EMQs allows trainees to test themselves on everything they need to know to pass the MRCS Part A exam.
Author: David B. Williams Publisher: Springer Science & Business Media ISBN: 1475725191 Category : Science Languages : en Pages : 708
Book Description
Electron microscopy has revolutionized our understanding the extraordinary intellectual demands required of the mi of materials by completing the processing-structure-prop croscopist in order to do the job properly: crystallography, erties links down to atomistic levels. It now is even possible diffraction, image contrast, inelastic scattering events, and to tailor the microstructure (and meso structure ) of materials spectroscopy. Remember, these used to be fields in them to achieve specific sets of properties; the extraordinary abili selves. Today, one has to understand the fundamentals ties of modem transmission electron microscopy-TEM of all of these areas before one can hope to tackle signifi instruments to provide almost all of the structural, phase, cant problems in materials science. TEM is a technique of and crystallographic data allow us to accomplish this feat. characterizing materials down to the atomic limits. It must Therefore, it is obvious that any curriculum in modem mate be used with care and attention, in many cases involving rials education must include suitable courses in electron mi teams of experts from different venues. The fundamentals croscopy. It is also essential that suitable texts be available are, of course, based in physics, so aspiring materials sci for the preparation of the students and researchers who must entists would be well advised to have prior exposure to, for carry out electron microscopy properly and quantitatively.
Author: H. Royden Jones Jr. Publisher: Elsevier Health Sciences ISBN: 1455733873 Category : Medical Languages : en Pages : 391
Book Description
Brain, Part 1 of The Netter Collection of Medical Illustrations: Nervous System, 2nd Edition, provides a highly visual guide to this complex organ, from basic neurodevelopment, neuroanatomy, neurophysiology, and cognition to classic disorders including to epilepsy, hypothalamus/pituitary with disorders of consciousness and sleep, movement disorders, cerebellum, stroke, multiple sclerosis, neurologic infections, neuro-oncology, headaches, and brain trauma. This spectacularly illustrated volume in the masterwork known as the (CIBA) Netter "Green Books" has been expanded and revised by Drs. H. Royden Jones, Jr., Ted M. Burns, Michael J. Aminoff, and Scott L. Pomeroy to mirror the many exciting advances in medicine and imaging - offering unparalleled insights into the broad clinical spectrum of brain disorders. - Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. - Get complete, integrated visual guidance on the brain with thorough, richly illustrated coverage. - Quickly understand complex topics thanks to a concise text-atlas format that provides a context bridge between primary and specialized medicine. - Clearly visualize how core concepts of anatomy, physiology, and other basic sciences correlate across disciplines. - Benefit from matchless Netter illustrations that offer precision, clarity, detail and realism as they provide a visual approach to the clinical presentation and care of the patient. - Gain a rich clinical view of all aspects of the brain in one comprehensive volume, conveyed through beautiful illustrations as well as up-to-date radiologic images. - Clearly see the connection between basic science and clinical practice with an integrated overview of normal structure and function as it relates to pathologic conditions. - Grasp current clinical concepts regarding development, pediatrics, and adult medicine captured in classic Netter illustrations, as well as new illustrations created specifically for this volume by artist-physician Carlos Machado, MD, and others working in the Netter style.
Author: Michael J. Aminoff Publisher: Elsevier Health Sciences ISBN: 0323882129 Category : Medical Languages : en Pages : 418
Book Description
Offering a concise, highly visual approach to the basic science and clinical pathology of the nervous system, this updated volume in The Netter Collection of Medical Illustrations (the CIBA "Green Books") contains unparalleled didactic illustrations reflecting the latest medical knowledge. Revised by Drs. Michael J. Aminoff, Scott L. Pomeroy, and Kerry H. Levin, Brain, Part 1 of the Nervous System, Volume 7, integrates core concepts of anatomy, physiology, and other basic sciences with common clinical correlates across health, medical, and surgical disciplines. Classic Netter art, updated and new illustrations, and modern imaging continue to bring medical concepts to life and make this timeless work an essential resource for students, clinicians, and educators. - Provides a highly visual guide to this complex organ, from basic neurodevelopment, neuroanatomy, neurophysiology, and cognition to a full range of disorders, including epilepsy, disorders of consciousness and sleep, movement disorders, stroke, multiple sclerosis, neurologic infections, neuro-oncology, headaches, and brain trauma. - Offers expanded coverage of timely topics like acute flaccid paralysis; neurological complications of COVID-19, ependymomas, genetics of epilepsy, and more. - Provides a concise overview of complex information by seamlessly integrating anatomical and physiological concepts using practical clinical scenarios. - Shares the experience and knowledge of Drs. Michael J. Aminoff, Scott L. Pomeroy, and Kerry H. Levin, with content overseen by experts at Harvard, UCSF, and other leading neurology centers. - Compiles Dr. Frank H. Netter's master medical artistry—an aesthetic tribute and source of inspiration for medical professionals for over half a century—along with new art in the Netter tradition for each of the major body systems, making this volume a powerful and memorable tool for building foundational knowledge and educating patients or staff. - NEW! An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud.
Author: Publisher: Academic Press ISBN: 0080957021 Category : Science Languages : en Pages : 617
Book Description
Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. - Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays - Discusses many new assays developed since the previous edition - Presents recent developments in cytometric intrumentation/technology
Author: J.P. Andersen
Author: J.P. Andersen
Author: Armin Kargol
Author: Pradip K Datta
Author: Edward Bittar
Author: Pradip K Datta
Author: David B. Williams
Author: United States. National Bureau of Standards
Author: H. Royden Jones Jr.
Author: Michael J. Aminoff
Author: