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Intervening against bovine trypanosomosis in eastern Africa

Intervening against bovine trypanosomosis in eastern Africa PDF Author: Food and Agriculture Organization of the United Nations
Publisher: Food & Agriculture Org.
ISBN: 925109781X
Category : Technology & Engineering
Languages : en
Pages : 120

Book Description
Eastern Africa’s livestock keepers face many challenges, not least the widespread prevalence of endemic diseases which both undermine animals’ productivity and increase livestock mortality. Tsetse- transmitted trypanosomosis causes significant economic losses, in particular in cattle. This study analyses these losses in a spatially explicit framework for the six tsetse-infested countries of the Intergovernmental Authority on Development (IGAD) region: Ethiopia, Kenya, Somalia, South Sudan, Sudan and Uganda. The cattle production systems of the region are diverse, ranging from pastoralism to agropastoralist and mixed crop-livestock farming. Some areas make extensive use of draught cattle or of high yielding crossbred dairy cows. Based on these features, twelve cattle production systems in the region were characterized and mapped. In these systems, the potential incomes from cattle production were modeled for a situation with and without trypanosomosis; the models looked at mortality, fertility, other productivity parameters and cattle population growth and expansion. The results of the analysis were used to generate a map of the potential benefits of controlling the disease. Estimates were then made of the costs of tsetse and trypanosomosis control using a range of techniques, namely: trypanocidal drugs; control or localized elimination of tsetse flies using insecticide-treated cattle or targets, aerial spraying and the sterile insect technique. The mapped potential benefits and mapped estimated costs were combined in order to produce a series of benefit-cost maps which illustrate what techniques are likely to be the most economically attractive in different areas of the study region. The suite of tools and economic analyses documented in this paper provide essential information to decision makers for comparing and prioritizing interventions in the region.

Intervening against bovine trypanosomosis in eastern Africa

Intervening against bovine trypanosomosis in eastern Africa PDF Author: Food and Agriculture Organization of the United Nations
Publisher: Food & Agriculture Org.
ISBN: 925109781X
Category : Technology & Engineering
Languages : en
Pages : 120

Book Description
Eastern Africa’s livestock keepers face many challenges, not least the widespread prevalence of endemic diseases which both undermine animals’ productivity and increase livestock mortality. Tsetse- transmitted trypanosomosis causes significant economic losses, in particular in cattle. This study analyses these losses in a spatially explicit framework for the six tsetse-infested countries of the Intergovernmental Authority on Development (IGAD) region: Ethiopia, Kenya, Somalia, South Sudan, Sudan and Uganda. The cattle production systems of the region are diverse, ranging from pastoralism to agropastoralist and mixed crop-livestock farming. Some areas make extensive use of draught cattle or of high yielding crossbred dairy cows. Based on these features, twelve cattle production systems in the region were characterized and mapped. In these systems, the potential incomes from cattle production were modeled for a situation with and without trypanosomosis; the models looked at mortality, fertility, other productivity parameters and cattle population growth and expansion. The results of the analysis were used to generate a map of the potential benefits of controlling the disease. Estimates were then made of the costs of tsetse and trypanosomosis control using a range of techniques, namely: trypanocidal drugs; control or localized elimination of tsetse flies using insecticide-treated cattle or targets, aerial spraying and the sterile insect technique. The mapped potential benefits and mapped estimated costs were combined in order to produce a series of benefit-cost maps which illustrate what techniques are likely to be the most economically attractive in different areas of the study region. The suite of tools and economic analyses documented in this paper provide essential information to decision makers for comparing and prioritizing interventions in the region.

Environmentally Sustainable Livestock Production

Environmentally Sustainable Livestock Production PDF Author: Ilkka Leinonen
Publisher: MDPI
ISBN: 3038975524
Category : Environmental sciences
Languages : en
Pages : 291

Book Description
This book is a printed edition of the Special Issue "Environmentally Sustainable Livestock Production" that was published in Sustainability

The Trypanosomiases

The Trypanosomiases PDF Author: Ian Maudlin
Publisher: CABI
ISBN: 9780851990347
Category : Medical
Languages : en
Pages : 644

Book Description
This state-of-the-art reference book includes comprehensive coverage of the biology and control of African, Asian and South American trypanosomiasis ("sleeping sickness") in man and animals. It describes recent research developments in the biology and molecular biology of trypanosomes (the protozoan parasite) and their vectors, and methods in diagnosis and control, such as trapping tsetse fly vectors. Different sections of the book are devoted to biology of trypanosomes, vector biology, epidemiology and diagnosis, pathogenesis, disease impact, chemotherapy and disease control, and vector control. The book contains contributions from leading experts from Europe, North and South America, and Africa.

Atlas of African agriculture research and development

Atlas of African agriculture research and development PDF Author: Sebastian, Kate
Publisher: Intl Food Policy Res Inst
ISBN: 0896298469
Category : Social Science
Languages : en
Pages : 108

Book Description
The Atlas of African Agriculture Research & Development is a multifaceted resource that high­lights the ubiquitous nature of smallholder agriculture in Africa; the many factors shaping the location, nature, and performance of agricultural enterprises; and the strong interde­pendencies among farming, natural resource stocks and flows, rural infrastructure, and the well-being of the poor.

Drivers of Change

Drivers of Change PDF Author: Trabucco, Antonio
Publisher: Intl Food Policy Res Inst
ISBN:
Category : Social Science
Languages : en
Pages : 13

Book Description
The Atlas of African Agriculture Research & Development is a multifaceted resource that high­lights the ubiquitous nature of smallholder agriculture in Africa; the many factors shaping the location, nature, and performance of agricultural enterprises; and the strong interde­pendencies among farming, natural resource stocks and flows, rural infrastructure, and the well-being of the poor.

Combating and Controlling Nagana and Tick-Borne Diseases in Livestock

Combating and Controlling Nagana and Tick-Borne Diseases in Livestock PDF Author: Orenge, Caleb Oburu
Publisher: IGI Global
ISBN: 1799864359
Category : Science
Languages : en
Pages : 440

Book Description
African animal trypanosomosis (AAT), also called nagana, is a trans-boundary disease that has had an immense impact on cattle and is ranked among the top global cattle diseases. This and tick-borne diseases have caused major obstacles to sustainable livestock-based agricultural production and food security and are important factors in underdevelopment. Due to decreasing efficacy of available drugs, widespread trypanosome resistance, and the difficulty of sustaining other control measures, there is a need for alternative sustainable strategies to reduce the impact these diseases have on livestock. Combating and Controlling Nagana and Tick-Borne Diseases in Livestock provides the latest empirical research findings on the effects of African animal trypanosomiasis (nagana) and tick-borne disease infection in livestock, their impact on farmer livelihoods, and the measures that can be undertaken to mitigate negative effects and reduce the number of infections. While highlighting topic areas such as disease history and transmission, treatments, and the economic impacts, this book is essential for farmers, animal health and animal production professionals and practitioners, non-government organizations, researchers, academicians, and students working in fields that include but are not limited to agriculture, livestock production, environmental science, veterinary medicine, veterinary pathology, and epidemiology.

The Mononuclear Phagocyte System in Infectious Disease

The Mononuclear Phagocyte System in Infectious Disease PDF Author: Geanncarlo Lugo-Villarino
Publisher: Frontiers Media SA
ISBN: 2889630579
Category :
Languages : en
Pages : 790

Book Description
The Mononuclear Phagocyte System (MPS) of vertebrates is composed of monocytes, macrophages and dendritic cells. Together, they form part of the first line of immune defense against a variety of pathogens (bacteria, fungi, parasites and viruses), and thus play an important role in maintaining organism homeostasis. The mode of transmission, type of replication and mechanism of disease-causing differ significantly for each pathogen, eliciting a unique immune response in the host. Within this context, the MPS acts as both the sentinel and tailor of the immune system. As sentinels, MPS cells are found in blood and within tissues throughout the body to patrol against pathogenic insult. The strategy to detect 'microbial non-self' relies on MPS to recognize conserved microbial products known as 'pathogen-associated molecular pattern' (PAMPs). PAMPs recognition represents a checkpoint in the response to pathogens and relies on conserved 'pattern recognition receptors' (PRRs). Upon PRR engagement, MPS mount a cell-autonomous attack that includes the internalization and compartmentalization of intracellular pathogens into toxic compartments that promote destruction. In parallel, MPS cells launch an inflammatory response composed of a cellular arm and soluble factors to control extracellular pathogens. In cases when innate immunity fails to eliminate the invading microbe, MPS serves as a tailor to generate adaptive immunity for pathogen eradication and generation of "memory" cells, thus ensuring enhanced protection against re-infection. Indeed, MPS cell functions comprise the capture, process, migration and delivery of antigenic information to lymphoid organs, where type-1 immunity is tailored against intracellular microbes and type-2 immunity against extracellular pathogens. However, this potent adaptive immunity is also a double-edge sword that can cause aberrant inflammatory disorders, like autoimmunity or chronic inflammation. For this reason, MPS also tailors tolerance immunity against unwanted inflammation. Successful clearance of the microbe results in its destruction and proper collection of debris, resolution of inflammation and tissue healing for which MPS is essential. Reciprocally, as part of the evolutionary process taking place in all organisms, microbes evolved strategies to circumvent the actions bestowed by MPS cells. Multiple pathogens modulate the differentiation, maturation and activation programs of the MPS, as an efficient strategy to avoid a dedicated immune response. Among the most common evasion strategies are the subversion of phagocytosis, inhibition of PRR-mediated immunity, resistance to intracellular killing by reactive oxygen and nitrogen species, restriction of phagosome maturation, modulation of cellular metabolism and nutrient acquisition, regulation of cell death and autophagy, and modulation of pro-inflammatory responses and hijacking of tolerance mechanisms, among others. The tenet of this eBook is that a better understanding of MPS in infection will yield insights for development of therapeutics to enhance antimicrobial processes or dampen detrimental inflammation for the host's benefit. We believe that contributions to this topic will serve as a platform for discussion and debate about relevant issues and themes in this field. Our aim is to bring expert junior and senior scientists to address recent progress, highlight critical knowledge gaps, foment scientific exchange, and establish conceptual frameworks for future MPS investigation in the context of infectious disease.

The Epidemiology, Diagnosis and Prevention of Infectious Diseases in Livestock

The Epidemiology, Diagnosis and Prevention of Infectious Diseases in Livestock PDF Author: Satoshi Sekiguchi
Publisher: Frontiers Media SA
ISBN: 288974518X
Category : Medical
Languages : en
Pages : 468

Book Description


Prospects for Livestock-Based Livelihoods in Africa's Drylands

Prospects for Livestock-Based Livelihoods in Africa's Drylands PDF Author: Cornelis de Haan
Publisher: World Bank Publications
ISBN: 1464808392
Category : Business & Economics
Languages : en
Pages : 199

Book Description
Prospects for Livestock-Based Livelihoods in Africa's Drylands examines the challenges and opportunities facing the livestock sector and the people who depend on livestock in the dryland regions of Sub-Saharan Africa. It presents a novel way of thinking about pastoral development, grounded in a conceptual framework that focuses on the multiple shocks that drylands livestock keepers face and how those shocks can be addressed, drawing on a state-of-the-art literature review carried out by scientists of leading research institutes and development organizations, and integrating the results of an innovative approach to modeling development options for the drylands livestock sector. Looking to the future, the picture is mixed. On the positive side, demand for red meat is expected to strengthen in domestic and regional markets, suggesting that livestock keepers will have good market opportunities. On the negative side, a large majority of livestock keepers are classifi ed as poor, and the natural (feed) resource base is likely to be suffi cient to enable improved meat and milk production for the growing human population. Prospects for the livestock sector through 2030 vary by aridity zone. In arid and semi-arid zones, a reasonable goal for 2030 is to have land use, training, and microfi nance systems established that promote an appropriate balance between human and livestock carrying capacities, featuring mainly grassland/pastoral systems that reliably and sustainably satisfy the minimum income needs of herder households, produce at least a signifi cant part of the demand in local markets for animal source food, and provide environmental services for which livestock keepers receive compensation. The goal includes signifi cant employment generation outside the sector. In the higher rainfall zones of the semi-arid areas, and in the subhumid zones, a reasonable goal for 2030 is to have intensifi ed production systems established, featuring mainly mixed livestock/arable farming or agro-pastoral systems that are closely linked to nearby grassland/pastoral systems and that consistently generate marketable surpluses of differentiated red meat and livestock products that can compete not only in the expanding domestic market but also in selected regional markets.

One Health, 2nd Edition

One Health, 2nd Edition PDF Author: Jakob Zinsstag
Publisher: CABI
ISBN: 1789242576
Category : Medical
Languages : en
Pages : 459

Book Description
One Health, the concept of combined veterinary and human health, has now expanded beyond emerging infectious diseases and zoonoses to incorporate a wider suite of health issues. Retaining its interdisciplinary focus which combines theory with practice, this new edition illustrates the contribution of One Health collaborations to real-world issues such as sanitation, economics, food security and vaccination programmes. It includes more non-infectious disease issues and climate change discussion alongside revised case studies and expanded methodology chapters to draw out implications for practice. Promoting an action-based, solutions-oriented approach, One Health: The Theory and Practice of Integrated Health Approaches highlights the lessons learned for both human and animal health professionals and students.