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Author: Ulrich Mohr Publisher: Springer Science & Business Media ISBN: 3662079739 Category : Medical Languages : en Pages : 487
Book Description
Scientists from both academia and industry in many countries have closely cooperated to arrive at a consensus on the descriptions of all the types of tumour and preneoplastic lesions encountered in laboratory mice. The series of fascicles should provide information and guidelines especially adapted for international use in practical toxicologic pathology. Images showing the typical appearance of the discussed lesions and references to the most recently published papers complete the information presented here.
Author: Ulrich Mohr Publisher: Springer Science & Business Media ISBN: 3662079739 Category : Medical Languages : en Pages : 487
Book Description
Scientists from both academia and industry in many countries have closely cooperated to arrive at a consensus on the descriptions of all the types of tumour and preneoplastic lesions encountered in laboratory mice. The series of fascicles should provide information and guidelines especially adapted for international use in practical toxicologic pathology. Images showing the typical appearance of the discussed lesions and references to the most recently published papers complete the information presented here.
Author: Thomas C. Jones Publisher: Springer Science & Business Media ISBN: 3642610420 Category : Medical Languages : en Pages : 368
Book Description
Approximately ten years have elapsed since the second volume of the International Life Sciences Institute (ILSI) Monographs on Pathology of Laboratory Animals, Respiratory System, was first completed. New in formation of interest to pathologists has developed at a rather remark able pace during these years. Exceptional progress has been made in the routine identification of enzymes and cell products in respiratory cells. A better understanding has developed on the functions of cells of the respiratory tract and of the mechanisms involved in cell metabolism, particularly those involving toxins and carcinogens. Clear concepts have developed concerning the significance of pathologic lesions, particularly in the upper respiratory tract and their relation to human health and risk assessment. Standardized nomenclature has developed significantly dur ing the lO-year period since the first edition and is being utilized on an international basis. This has resulted in significant improvement in com munication of pathologic data to regulatory agencies and in scientific publications worldwide. This monograph series and others sponsored by ILSI have had significant effects on these improved communications and the international acceptance of standardized nomenclature. In this sec ond edition, new formats have been used where more appropriate for the subjects to be covered.
Author: Hans Hedrich Publisher: Academic Press ISBN: 0123820081 Category : Medical Languages : en Pages : 869
Book Description
"Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse"--Provided by publisher.
Author: Ching-Hung Hsu Publisher: John Wiley & Sons ISBN: 1118035127 Category : Science Languages : en Pages : 727
Book Description
With a weight-of-the-evidence approach, cancer risk assessment indentifies hazards, determines dose-response relationships, and assesses exposure to characterize the true risk. This book focuses on the quantitative methods for conducting chemical cancer risk assessments for solvents, metals, mixtures, and nanoparticles. It links these to the basic toxicology and biology of cancer, along with the impacts on regulatory guidelines and standards. By providing insightful perspective, Cancer Risk Assessment helps researchers develop a discriminate eye when it comes to interpreting data accurately and separating relevant information from erroneous.
Author: Philip Wexler Publisher: Academic Press ISBN: 0127447709 Category : Medical Languages : en Pages : 953
Book Description
History: -- K.D. Watson, P. Wexler, and J. Everitt. -- Highlights in the History of Toxicology. -- Selected References in the History of Toxicology. -- A Historical Perspective of Toxicology Information Systems. -- Books and Special Documents: -- G.L. Kennedy, Jr., P. Wexler, N.S. Selzer, and L.A. Malley. -- General Texts. -- Analytical Toxicology. -- Animals in Research. -- Biomonitoring/Biomarkers. -- Biotechnology. -- Biotoxins. -- Cancer. -- Chemical Compendia. -- Chemical--Cosmetics and Other Consumer. -- Products. -- Chemical--Drugs. -- Chemical--Dust and Fibers. -- Chemical--Metals. -- Chemicals--Pesticides -- Chemicals--Solvents. -- Chemical--Selected Chemicals. -- Clinical Toxicology. -- Developmental and Reproductive Toxicology. -- Environmental Toxicology--General. -- Environmental Toxicology-- Aquatic. -- Environmental Toxicology--Atmospheric. -- Environmental Toxicology--Hazardous Waste. -- Environmental Toxicology--Terrestrial. -- Environmental Toxicology--Wildlife. -- Ep ...
Author: United States. Public Health Service. Office of the Surgeon General Publisher: ISBN: Category : Government publications Languages : en Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Ulrich Mohr
Author: Ulrich Mohr
Author: 
Author: Ulrich Mohr
Author: Thomas C. Jones
Author: Hans Hedrich
Author: Ching-Hung Hsu
Author: Philip Wexler
Author: Peter Greaves
Author: Alecsandru Ioan Baba
Author: United States. Public Health Service. Office of the Surgeon General