Author: Simon Charles HeathPublisher: Frontiers Media SA
ISBN: 283253645X
Category : Science
Languages : en
Pages : 172
Book Description
This Research Topic is part of the Insights in Frontiers in Genetics series.
Insights in Statistical Genetics and Methodology: 2022
Author: Simon Charles HeathPublisher: Frontiers Media SA
ISBN: 283253645X
Category : Science
Languages : en
Pages : 172
Book Description
This Research Topic is part of the Insights in Frontiers in Genetics series.
Data Mining and Statistical Methods for Knowledge Discovery in Diseases Based on Multimodal Omics
Author: Jiajie PengPublisher: Frontiers Media SA
ISBN: 2889761746
Category : Science
Languages : en
Pages : 160
Book Description
Forensic Investigative Genetic Genealogy and Fine-Scale Structure of Human Populations
Author: Guanglin HePublisher: Frontiers Media SA
ISBN: 2832513670
Category : Science
Languages : en
Pages : 150
Book Description
Advances in Statistical Methods for the Genetic Dissection of Complex Traits in Plants
Author: Yuan-Ming ZhangPublisher: Frontiers Media SA
ISBN: 2832543693
Category : Science
Languages : en
Pages : 278
Book Description
Genome-wide association studies (GWAS) have been widely used in the genetic dissection of complex traits. However, there are still limits in current GWAS statistics. For example, (1) almost all the existing methods do not estimate additive and dominance effects in quantitative trait nucleotide (QTN) detection; (2) the methods for detecting QTN-by-environment interaction (QEI) are not straightforward and do not estimate additive and dominance effects as well as additive-by-environment and dominance-by-environment interaction effects, leading to unreliable results; and (3) no or too simple polygenic background controls have been employed in QTN-by-QTN interaction (QQI) detection. As a result, few studies of QEI and QQI for complex traits have been reported based on multiple-environment experiments. Recently, new statistical tools, including 3VmrMLM, have been developed to address these needs in GWAS. In 3VmrMLM, all the trait-associated effects, including QTN, QEI and QQI related effects, are compressed into a single effect-related vector, while all the polygenic backgrounds are compressed into a single polygenic effect matrix. These compressed parameters can be accurately and efficiently estimated through a unified mixed model analysis. To further validate these new GWAS methods, particularly 3VmrMLM, they should be rigorously tested in real data of various plants and a wide range of other species.
Systems Genetics of Human Complex Diseases - Volume II
Author: Guiyou LiuPublisher: Frontiers Media SA
ISBN: 2889768287
Category : Science
Languages : en
Pages : 222
Book Description
Methods for Ecological Research on Terrestrial Small Mammals
Author: Robert McCleeryPublisher: JHU Press
ISBN: 1421442124
Category : Science
Languages : en
Pages : 381
Book Description
All the information researchers, students, and practitioners need to conducted innovative, state-of-the-art research on small mammals. Rodents and insectivores constitute the vast majority of mammals on our planet, yet we often overlook the importance of this group. As seed dispersers, prey species, and disease regulators, these animals are critical to the functioning of our ecological systems. While considerable material exists that describes these species, there has been no dedicated guide explaining how to effectively research them—until now. Methods for Ecological Research on Terrestrial Small Mammals is a one-stop resource compiling all the information readers need to conduct state-of-the-art research on small terrestrial mammals across the globe. The authors cover the full spectrum of issues, from capture, handling, identification, reproduction, demography, and taxonomy to behavior, diet, evolution, diseases, movements, morphometrics, and more. They also: • highlight the latest techniques while carefully explaining the tried-and-tested methods needed to conduct rigorous scientific inquiries; • provide step-by-step examples and case studies, demonstrating how the methods discussed can be used in actual research projects; • compare and contrast methodologies, analytical techniques, and software packages, helping researchers determine which pathways and tools will yield the best results for their studies. A comprehensive and invaluable resource, Methods for Ecological Research on Terrestrial Small Mammals is a must-have for any ecologist working on small mammals.
Application of Novel Statistical and Machine-learning Methods to High-dimensional Clinical Cancer and (Multi-)Omics data
Author: Chao XuPublisher: Frontiers Media SA
ISBN: 2889714365
Category : Science
Languages : en
Pages : 136
Book Description
Statistical Approaches in Omics Data Association Studies
Author: Qi YanPublisher: Frontiers Media SA
ISBN: 2889763625
Category : Science
Languages : en
Pages : 169
Book Description
Genetics of familial hypercholesterolemia: New insight - Volume II
Author: Alpo Juhani VuorioPublisher: Frontiers Media SA
ISBN: 2832507778
Category : Science
Languages : en
Pages : 162
Book Description
System Biology Methods and Tools for Integrating Omics Data - Volume II
Author: Liang ChengPublisher: Frontiers Media SA
ISBN: 2889769151
Category : Science
Languages : en
Pages : 158
Book Description