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Author: Edward B. Ilgren Publisher: CRC Press ISBN: 9780849344077 Category : Medical Languages : en Pages : 936
Book Description
Initiation and Promotion in Skin or Liver Neoplasia is the only source of its kind that presents a comprehensive compilation of in vivo initiation/promotion studies that involve neoplastic changes in the skin or liver of experimental animals. The book surveys world literature over the past 65 years from almost 2,000 original studies covering nearly 200 journals in 9 languages. Publications reviewed consist of primary peer-reviewed papers, as well as those abstracts, meeting reports, and review articles, containing original data. Papers measuring both pre-neoplastic or neoplastic changes are included. The summaries for each study included in the book are highly formatted resumes that have four principal components which indicate: 1) What was done in the study; 2) How the study was done (e.g, methods); 3) The precise results obtained; 4) Individual critiques using GLP (Good Lab Practice) standards. Initiation and Promotion in Skin or Liver Neoplasia provides an indispensable abstracted reference resource for scientists, toxicologists, cancer researchers, litigators, regulators, environmentalists, policy analysts, and industry-based investigators.
Author: Edward B. Ilgren Publisher: CRC Press ISBN: 9780849344077 Category : Medical Languages : en Pages : 936
Book Description
Initiation and Promotion in Skin or Liver Neoplasia is the only source of its kind that presents a comprehensive compilation of in vivo initiation/promotion studies that involve neoplastic changes in the skin or liver of experimental animals. The book surveys world literature over the past 65 years from almost 2,000 original studies covering nearly 200 journals in 9 languages. Publications reviewed consist of primary peer-reviewed papers, as well as those abstracts, meeting reports, and review articles, containing original data. Papers measuring both pre-neoplastic or neoplastic changes are included. The summaries for each study included in the book are highly formatted resumes that have four principal components which indicate: 1) What was done in the study; 2) How the study was done (e.g, methods); 3) The precise results obtained; 4) Individual critiques using GLP (Good Lab Practice) standards. Initiation and Promotion in Skin or Liver Neoplasia provides an indispensable abstracted reference resource for scientists, toxicologists, cancer researchers, litigators, regulators, environmentalists, policy analysts, and industry-based investigators.
Author: Elizabeth K. Weisburger Publisher: Springer Science & Business Media ISBN: 9400925263 Category : Medical Languages : en Pages : 210
Book Description
but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.
Author: Robert C. Bast, Jr. Publisher: John Wiley & Sons ISBN: 111900084X Category : Medical Languages : en Pages : 2004
Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: United States. Public Health Service. Office of the Surgeon General Publisher: ISBN: Category : Government publications Languages : en Pages : 728
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Bharat B. Aggarwal Publisher: Springer ISBN: 3034808372 Category : Medical Languages : en Pages : 489
Book Description
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author: National Research Council Publisher: National Academies Press ISBN: 0309036879 Category : Nature Languages : en Pages : 476
Book Description
The most recent volume in the Drinking Water and Health series contains the results of a two-part study on the toxicity of drinking water contaminants. The first part examines current practices in risk assessment, identifies new noncancerous toxic responses to chemicals found in drinking water, and discusses the use of pharmacokinetic data to estimate the delivered dose and response. The second part of the book provides risk assessments for 14 specific compounds, 9 presented here for the first time.
Author: Edward B. Ilgren
Author: Edward B. Ilgren
Author: Ilgren EB.
Author: Elizabeth K. Weisburger
Author: Robert C. Bast, Jr.
Author: United States. Public Health Service. Office of the Surgeon General
Author: Bharat B. Aggarwal
Author: 
Author: 
Author: Alecsandru Ioan Baba
Author: National Research Council