Field Free Line Magnetic Particle Imaging PDF Download

Author: Marlitt Erbe
Publisher: Springer Science & Business Media
ISBN: 3658053372
Category : Technology & Engineering
Languages : en
Pages : 175

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Book Description
Marlitt Erbe provides a detailed introduction into the young research field of Magnetic Particle Imaging (MPI) and field free line (FFL) imaging in particular. She derives a mathematical description of magnetic field generation for FFL imaging in MPI. To substantiate the simulation studies on magnetic FFL generation with a proof-of-concept, the author introduces the FFL field demonstrator, which provides the world’s first experimentally generated rotated and translated magnetic FFL field complying with the requirements for FFL reconstruction. Furthermore, she proposes a scanner design of considerably enhanced magnetic field quality and efficiency. The author discusses the influence of magnetic field quality optimization on the image quality achieved using efficient Radon-based reconstruction methods, which arise for a line detection scheme and based on this optimized design, presents a dynamic FFL scanner assembly.

Author: Tobias Knopp
Publisher: Springer Science & Business Media
ISBN: 364204199X
Category : Medical
Languages : en
Pages : 211

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Book Description
This volume provides a comprehensive overview of recent developments in magnetic particle imaging (MPI), a novel imaging modality. Using various static and oscillating magnetic fields, and tracer materials made from iron oxide nanoparticles, MPI can perform background-free measurements of the particles’ local concentration. The method exploits the nonlinear remagnetization behavior of the particles and has the potential to surpass current methods for the detection of iron oxide in terms of sensitivity and spatiotemporal resolution. Starting from an introduction to the technology, the topics addressed include setting up an imaging device, assessment of image quality, development of new MPI tracer materials, and the first preclinical results. This is the first book to be published on magnetic particle imaging, and it will be an invaluable source of information for everyone with an interest in this exciting new modality.

Author: C. Alexiou
Publisher: Karger Medical and Scientific Publishers
ISBN: 380559819X
Category : Science
Languages : en
Pages : 211

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Book Description
Nanomedicine - the application of nanotechnology to human health - is a promising field of research at the interface of physical, chemical, biological, and medical science. Recent advances have made it possible to analyze biological systems at cellular and subcellular levels, offering numerous promising approaches to improve medical diagnosis and therapy. It is expected that nanomedicine will have a great impact especially on drug delivery and imaging. In this context, the development of targeted, highly specific nanoparticles is of pivotal importance. The results of these advances will offer personalized diagnostic tools and treatments in the future. Based on the 2nd Else Kröner-Fresenius-Symposium, this book presents a broad spectrum of topics ranging from nanoscale drug delivery/drug design to nanotoxicity and from diagnostics and imaging to therapeutic applications including antibody therapies. The contributions are authored by leading experts in the field and provide an excellent overview of the current knowledge in nanomedicine. Due to the interdisciplinary nature of the subject area this volume will be of special interest to physicians, biologists, chemists, engineers, and physicists as well as to students in the respective fields.

Author: Ernest D. Courant
Publisher:
ISBN:
Category : Particle accelerators
Languages : en
Pages : 42

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Author: Armin Iske
Publisher: Springer Nature
ISBN: 3031451589
Category : Computers
Languages : en
Pages : 165

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Book Description
This book describes recent collaborations combining the expertise of applied mathematicians, engineers and geophysicists within a research training group (RTG) on "Modeling, Simulation and Optimization of Fluid Dynamic Applications”, funded by the Deutsche Forschungsgemeinschaft (DFG). The focus is on mathematical modeling, adaptive discretization, approximation strategies and shape optimization with PDEs. The balanced research program is based on the guiding principle that mathematics drives applications and is inspired by applications. With this leitmotif the RTG advances research in Modeling, Simulation and Optimization by an interdisciplinary approach, i.e., to stimulate fundamental education and research by highly complex applications and at the simultaneously transfer tailored mathematical methods to applied sciences. The reported research involves nine projects and addresses challenging fluid dynamic problems inspired by applied sciences, such as climate research & meteorology, energy, aerospace & marine engineering, or medicine. More fundamental research concerning analysis, approximation and numerics is also covered. The material represents a successful attempt to exchange research paradigms between different disciplines and thus displays a modern approach to basic research into scientifically and societally relevant contemporary problems.

Author: Urs Häfeli
Publisher: Springer Science & Business Media
ISBN: 1475764820
Category : Science
Languages : en
Pages : 618

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Book Description
The discovery of uniform latex particles by polymer chemists of the Dow Chemical Company nearly 50 years ago opened up new exciting fields for scientists and physicians and established many new biomedical applications. Many in vitro diagnostic tests such as the latex agglutination tests, analytical cell and phagocytosis tests have since become rou tine. They were all developed on the basis of small particles bound to biological active molecules and fluorescent and radioactive markers. Further developments are ongoing, with the focus now shifted to applications of polymer particles in the controlled and di rected transport of drugs in living systems. Four important factors make microspheres interesting for in vivo applications: First, biocompatible polymer particles can be used to transport known amounts of drug and re lease them in a controlled fashion. Second, particles can be made of materials which bio degrade in living organisms without doing any harm. Third, particles with modified surfaces are able to avoid rapid capture by the reticuloendothelial system and therefore en hance their blood circulation time. Fourth, combining particles with specific molecules may allow organ-directed targeting.

Author: Helmut Wiedemann
Publisher: Springer Science & Business Media
ISBN: 3662029030
Category : Science
Languages : en
Pages : 457

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Book Description
Particle Accelerator Physics covers the dynamics of relativistic particle beams, basics of particle guidance and focusing, lattice design, characteristics of beam transport systems and circular accelerators. Particle-beam optics is treated in the linear approximation including sextupoles to correct for chromatic aberrations. Perturbations to linear beam dynamics are analyzed in detail and correction measures are discussed, while basic lattice design features and building blocks leading to the design of more complicated beam transport systems and circular accelerators are studied. Characteristics of synchrotron radiation and quantum effects due to the statistical emission of photons on particle trajectories are derived and applied to determine particle-beam parameters. The discussions specifically concentrate on relativistic particle beams and the physics of beam optics in beam transport systems and circular accelerators such as synchrotrons and storage rings. This book forms a broad basis for further, more detailed studies of nonlinear beam dynamics and associated accelerator physics problems, discussed in the subsequent volume.

Author: Wilfried Andrä
Publisher: John Wiley & Sons
ISBN: 3527610189
Category : Medical
Languages : en
Pages : 655

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Book Description
This second, completely updated and extended edition of the only reference work in this growing field of medical physics focuses on biomagnetic instrumentation as well as applications in cardiology and neurology. New chapters have been added on fetal magnetography and magnetic field therapy, as well as the safety aspects of magnetic fields. Written by well-known specialists from Germany, USA, Canada, Japan, the Netherlands and Scandinavia, the result is a manual for researchers in this field as well as for those who apply modern methods based on magnetism in medical practice. It equally provides a detailed overview for newcomers to the field as well as for experts familiar with only one part of the area.

Author: Karl Johan Åström
Publisher: Princeton University Press
ISBN: 069121347X
Category : Technology & Engineering
Languages : en
Pages :

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Book Description
The essential introduction to the principles and applications of feedback systems—now fully revised and expanded This textbook covers the mathematics needed to model, analyze, and design feedback systems. Now more user-friendly than ever, this revised and expanded edition of Feedback Systems is a one-volume resource for students and researchers in mathematics and engineering. It has applications across a range of disciplines that utilize feedback in physical, biological, information, and economic systems. Karl Åström and Richard Murray use techniques from physics, computer science, and operations research to introduce control-oriented modeling. They begin with state space tools for analysis and design, including stability of solutions, Lyapunov functions, reachability, state feedback observability, and estimators. The matrix exponential plays a central role in the analysis of linear control systems, allowing a concise development of many of the key concepts for this class of models. Åström and Murray then develop and explain tools in the frequency domain, including transfer functions, Nyquist analysis, PID control, frequency domain design, and robustness. Features a new chapter on design principles and tools, illustrating the types of problems that can be solved using feedback Includes a new chapter on fundamental limits and new material on the Routh-Hurwitz criterion and root locus plots Provides exercises at the end of every chapter Comes with an electronic solutions manual An ideal textbook for undergraduate and graduate students Indispensable for researchers seeking a self-contained resource on control theory

Author: Andreas Maier
Publisher: Springer
ISBN: 3319965204
Category : Computers
Languages : en
Pages : 263

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Book Description
This open access book gives a complete and comprehensive introduction to the fields of medical imaging systems, as designed for a broad range of applications. The authors of the book first explain the foundations of system theory and image processing, before highlighting several modalities in a dedicated chapter. The initial focus is on modalities that are closely related to traditional camera systems such as endoscopy and microscopy. This is followed by more complex image formation processes: magnetic resonance imaging, X-ray projection imaging, computed tomography, X-ray phase-contrast imaging, nuclear imaging, ultrasound, and optical coherence tomography.