Impact of Trans-10, Cis-12 Conjugated Linoleic Acid on Interleukin (IL)-6 and IL-8 and Adipogenic Genes in Cultures of Human Adipose Tissue Explants PDF Download

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Impact of Trans-10, Cis-12 Conjugated Linoleic Acid on Interleukin (IL)-6 and IL-8 and Adipogenic Genes in Cultures of Human Adipose Tissue Explants

Impact of Trans-10, Cis-12 Conjugated Linoleic Acid on Interleukin (IL)-6 and IL-8 and Adipogenic Genes in Cultures of Human Adipose Tissue Explants PDF Author: James Nathan Provo
Publisher:
ISBN:
Category : Linoleic acid
Languages : en
Pages :

Book Description
"Obesity has reached epidemic proportions in the United States, currently ranking second among causes of preventable deaths. Our research group has shown in cultures of differentiated human adipocytes that 30 uM trans-10, cis-12 Conjugated Linoleic Acid (CLA) increases IL-6 and IL-8 secretion into the media and lowers mRNA levels of peroxisome proliferator-activated receptor gamma (PPARī§). Human adipose tissue explants were incubated with either vehicle or 30 uM trans-10, cis-12 CLA for 8, 24, or 72 h. Trans-10, cis-12 CLA treatment increased IL-6 and IL-8 secretion into the media (p
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