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Author: Jeffrey M. Jacobson Publisher: Springer Science & Business Media ISBN: 159259171X Category : Medical Languages : en Pages : 537
Book Description
In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers HIV-specific passive and active immunization strategies, gene therapy, and host cell-targeted approaches for treating HIV infection and restoring immune function.
Author: Jeffrey M. Jacobson Publisher: Springer Science & Business Media ISBN: 159259171X Category : Medical Languages : en Pages : 537
Book Description
In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers HIV-specific passive and active immunization strategies, gene therapy, and host cell-targeted approaches for treating HIV infection and restoring immune function.
Author: K. Noel Masihi Publisher: CRC Press ISBN: 9780824792091 Category : Medical Languages : en Pages : 542
Book Description
Based on the International Symposium on Immunotherapy of Infections held recently at the Robert Koch Institute, Berlin, Germany, this work discusses cytokines as well as synthetic and natural immunomodulators and their applications in the immunotherapy of bacterial, viral, parasitic and fungal infections.;The contributors describe innovative treatment concepts that act as adjuncts to established therapies for the control of both existing and newly emerging infectious diseases.
Author: National Research Council Publisher: National Academies Press ISBN: 0309180686 Category : Medical Languages : en Pages : 102
Book Description
Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Author: King K. Holmes Publisher: World Bank Publications ISBN: 1464805253 Category : Medical Languages : en Pages : 1027
Book Description
Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.
Author: K.Noel Masihi Publisher: Springer Science & Business Media ISBN: 3642761208 Category : Medical Languages : en Pages : 378
Book Description
The prevention and control of infectious diseases represents, even today, an important public health problem for responsible national and international authorities. Newly emerging p.athogens such as human immunodeficiency virus (HIV) , legionella, and bovine spongiform encephalopathy (BSE) have captured current public awareness. Despite significant success against smallpox, polio myelitis, mumps, and measles, the vast majority of infectious diseases are yet to be satisfactorily controlled. Limited efficacy of some vaccines, e. g., against influenza viruses, or their nonavailability have hampered an effective control of many infections. A meaningful reduction of the health risks posed by microbial pathogens is of crucial importance. Increased efforts need to be exerted in areas of active and passive immunization as well as in stimulation of enhanced nonspecific resistance .. Progress in the field of infectious diseases can be accelerated when a generation of new improved vaccines are developed. These vaccines should be capable of activat ing the cellular and the humoral immune responses as well as inducing persistent immunological memory. Development of novel regimens for enhancing natural resistance against infections is also progressively gaining in importance. The urgency increases as chemotherapy against viral and other infections further continues to be plagued by a carousel of a limited number of licensed drugs, problems of side effects, and development of drug resistance. It is becoming expedient that future strategies embrace a policy directed towards triggering mechanisms capable of inducing specific and nonspecific host defences.
Author: Saba Tufail Publisher: Frontiers Media SA ISBN: 2832550029 Category : Medical Languages : en Pages : 115
Book Description
Infectious diseases have jeopardized human health significantly as evidenced by the ongoing Covid-19 pandemic. In recent years, the world has witnessed outbreaks of many emerging and re-emerging infections such as SARS (most recent by SARS-CoV-2), Ebola, Zika, MERS, dengue which in addition to taking millions of lives, have posed major health issues in recovered individuals. Moreover, several infectious agents like hepatitis B and C viruses, human papillomavirus, human immunodeficiency virus type 1, Epstein-Barr virus, human T-cell leukemia/lymphoma virus type 1, Kaposi sarcoma-associated herpesvirus, Helicobacter pylori and Streptococcus bovis have been found to cause different types of cancers since the action mechanism of these agents sometimes transforms an infected cell into a cancer cell. As these infections are difficult to treat with available drugs owing to their lower efficacy, toxicity and emergence of drug resistance; immunotherapy is viewed as a viable option.
Author: Ann Arvin Publisher: Cambridge University Press ISBN: 1139461648 Category : Medical Languages : en Pages : 1325
Book Description
This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Author: Manzoor Ahmad Mir Publisher: Academic Press ISBN: 0128026758 Category : Medical Languages : en Pages : 320
Book Description
Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation. The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases. - Highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy - Provides the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families - Targets new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases
Author: Jeffrey M. Jacobson
Author: Jeffrey M. Jacobson
Author: K. Noel Masihi
Author: Jeffrey M Jacobson
Author: National Research Council
Author: James A. Reinarz
Author: King K. Holmes
Author: K.Noel Masihi
Author: Saba Tufail
Author: Ann Arvin
Author: Manzoor Ahmad Mir