Imaging of Inflammation and Infection in Cardiovascular Diseases PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Imaging of Inflammation and Infection in Cardiovascular Diseases PDF full book. Access full book title Imaging of Inflammation and Infection in Cardiovascular Diseases by Federico Caobelli. Download full books in PDF and EPUB format.
Author: Federico Caobelli Publisher: Springer Nature ISBN: 303081131X Category : Medical Languages : en Pages : 274
Book Description
This book addresses the most relevant imaging techniques in order to detect inflammation and infection in the most common cardiovascular diseases. The book presents data concerning molecular imaging (SPECT and PET) and cardiac magnetic resonance imaging (MRI) for each disease, with a special focus on the emerging role of hybrid PET/MR imaging. Different non-ischemic and ischemic diseases as well as cardiac infections are addressed in detail; these include: Cardiac sarcoidosis, Cardiac amyloidosis, the vulnerable plaque, Post-infarction inflammatory alterations, Pericarditis, Myocarditis, Cardiac devices infections, and Endocarditis. The book also provides a comprehensive discussion on new targets and new tracers, to date mostly investigated at a pre-clinical stage, thus constituting an excellent basis for translational imaging. Imaging of Inflammation and Infection in Cardiovascular Diseases will be of interest not only for experts in clinical imaging, but also pre-clinical scientists and will be invaluable for both nuclear medicine physicians and radiologists.
Author: Federico Caobelli Publisher: Springer Nature ISBN: 303081131X Category : Medical Languages : en Pages : 274
Book Description
This book addresses the most relevant imaging techniques in order to detect inflammation and infection in the most common cardiovascular diseases. The book presents data concerning molecular imaging (SPECT and PET) and cardiac magnetic resonance imaging (MRI) for each disease, with a special focus on the emerging role of hybrid PET/MR imaging. Different non-ischemic and ischemic diseases as well as cardiac infections are addressed in detail; these include: Cardiac sarcoidosis, Cardiac amyloidosis, the vulnerable plaque, Post-infarction inflammatory alterations, Pericarditis, Myocarditis, Cardiac devices infections, and Endocarditis. The book also provides a comprehensive discussion on new targets and new tracers, to date mostly investigated at a pre-clinical stage, thus constituting an excellent basis for translational imaging. Imaging of Inflammation and Infection in Cardiovascular Diseases will be of interest not only for experts in clinical imaging, but also pre-clinical scientists and will be invaluable for both nuclear medicine physicians and radiologists.
Author: Elena Aikawa Publisher: Springer ISBN: 3319092685 Category : Medical Languages : en Pages : 394
Book Description
This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses.
Author: Wilbert S. Aronow Publisher: BoD – Books on Demand ISBN: 1789852757 Category : Medical Languages : en Pages : 187
Book Description
Inflammatory Heart Diseases presents comprehensive information on pericardial diseases, cardiomyopathies, and atherosclerotic cardiovascular diseases. Chapters are written by experts in the field and cover such topics as advanced concepts in pericardial disease, pericardial disease in the elderly, inflammation and diabetic cardiomyopathy, medical imaging in myocarditis, and the role of lifestyle in development of coronary heart disease, among others.
Author: Hongjun Li Publisher: Springer Nature ISBN: 981994614X Category : Medical Languages : en Pages : 420
Book Description
This user-friendly book provides a comprehensive overview of diagnostic imaging in infectious and inflammatory diseases in heart and chest. It starts with a general review of infectious diseases, including pathogenesis and pathology-radiology correlations. In separate chapters, the authors then introduce clinical images of typical bacterial, viral, fungal, and parasitic infections in a wide range of clinical conditions and circumstances. Each disease is clearly illustrated using cases combined with high-quality CT and MRI for readers to correctly identify causes of abnormalities. The book provides a valuable reference source for radiologists and doctors working in the area of infectious and inflammatory diseases.
Author: Elena Lazzeri Publisher: Springer Nature ISBN: 3030621758 Category : Medical Languages : en Pages : 364
Book Description
This atlas explores the latest advances in radionuclide imaging in the field of inflammatory diseases and infections, which now typically includes multimodality fusion imaging (e.g. in SPECT/CT and in PET/CT). In addition to describing the pathophysiologic and molecular mechanisms on which the radionuclide imaging of infection/inflammation is based, the clinical relevance and impact of such procedures are demonstrated in a collection of richly illustrated teaching cases, which describe the most commonly observed scintigraphic patterns, as well as anatomic variants and technical pitfalls. Special emphasis is placed on using tomographic multimodality imaging to increase both the sensitivity and specificity of radionuclide imaging. The aim of the second edition of this book is to update the first (published in 2013) by reflecting the changes in this rapidly evolving field. Particular attention is paid to the latest advances in the radionuclide imaging of infection and inflammation, including the expanding role of hybrid imaging with [18F]FDG PET/CT SPECT/CT, without neglecting new radiotracers proposed for the imaging of infection/inflammation. Written by respected experts in the field, the book will be an invaluable tool for residents in nuclear medicine, as well as for other specialists.
Author: Georg Wick Publisher: Springer Science & Business Media ISBN: 370910338X Category : Medical Languages : en Pages : 628
Book Description
It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.
Author: Matthieu Pelletier-Galarneau Publisher: Springer Nature ISBN: 3031098072 Category : Medical Languages : en Pages : 382
Book Description
This book is a clinically oriented, up-to-date, and in-depth review of the various applications of FDG-PET/CT and PET/MR in cardiovascular diseases with emphasis on the current available evidence. Positron emission tomography (PET) imaging with fluorodeoxyglucose (FDG) has seen increased applications in cardiovascular diseases over the last decades. Its utility is already established in a wide range of conditions, including myocardial viability imaging, assessment of inflammatory diseases such as sarcoidosis and vasculitis, as well as imaging of infectious processes, such as infective endocarditis and cardiac implantable electronic device infection. In addition, there are several emerging indications such as the imaging of left ventricular assisting device infection and native valve endocarditis as well as new applications under investigation. The first section of the book reviews the technical basis of cardiovascular PET/CT and PET/MR imaging as well as cardiac metabolism. The following chapters each present specific pathologies, presenting epidemiology, pathophysiology, and diagnostic strategies, along with high quality clinical cases to support the discussion. The final chapter is a review of 15 interesting and clinically relevant cases. This is an ideal guide for nuclear medicine physicians, cardiologists, radiologists, residents, post-graduate fellows, and technologists.
Author: Reece Joseph Goiffon Publisher: ISBN: Category : Electronic dissertations Languages : en Pages : 232
Book Description
Cardiovascular disease (CVD) is the leading cause of morbidity, mortality, and health care costs in the developed world and is often undiagnosed until clinical presentation with a major adverse cardiovascular event (MACE). Plasma myeloperoxidase (MPO) content is an emerging biomarker for risk, progression, and prognosis at different stages of CVD. Enzyme-linked immunosorbent assays (ELISAs) are currently used to measure clinical plasma MPO concentration, but ELISAs are costly and time-intensive. Luminol is a chemiluminescent compound with specificity for MPO activity in vivo, but is not sensitive enough for use as a bioluminescence reporter of plasma MPO oxidation. The luminol derivative L-012 is more sensitive to oxidation, but little is known about its sensitivity or specificity to reactive oxygen species (ROS) produced by MPO and its interactions with the myriad components of whole plasma. Therefore L-012 was first characterized as an MPO-dependent bioluminescence reporter in whole blood and plasma. The data indicated that L-012 is not a reporter of all MPO-dependent reactions, but specifically reports halogenation with chloride or bromide. Additionally, plasma components inhibited MPO both specifically and non-specifically and prevented precision measurement of plasma MPO activity with L-012 bioluminescence. To overcome this, a method was developed to isolate MPO on a solid substrate, remove small molecule antioxidants, and eliminate specific inhibition by plasma proteins. With this method, MPO activity from human samples could be assayed using bovine plasma supplemented with purified human MPO as calibration standards. The assay can be performed in under an hour, comprises only two steps, and uses no costly immunologic reagents. The assay was validated with a pilot study using 72 plasma samples from cardiology patients undergoing elective catheterization. Individuals in this cohort assayed by the bioluminescence method were concordant with a parallel ELISA within 2 ± 11 [mu]g/L MPO and overall the measurements from the two assays were not significantly different. To further validate the assay, an outside laboratory also measured MPO from 67 of the same plasma samples with an approved, clinical MPO ELISA. The newly developed MPO assay agreed with the outside ELISA on par with the parallel ELISA. In conclusion, a clinical assay for plasma MPO activity was developed with comparable sensitivity and specificity to current ELISAs which can be performed at a fraction of the time and cost.
Author: Abass Alavi Publisher: Elsevier Health Sciences ISBN: 0323678424 Category : Medical Languages : en Pages :
Book Description
This issue of PET Clinics focuses on PET-CT-MRI based Cardiovascular Imaging, and is edited by Drs. Abass Alavi (the Consulting Editor of PET Clinics), Poul Flemming Høilund-Carlsen, and Ali Salavati. Articles will include: Evolving role of PET in detecting and characterizing atherosclerosis; Applications of modern CT techniques in assessing cardiovascular disorders; Applications of conventional MRI techniques in assessing cardiovascular disorders; PET/CT Assessment of ischemic heart disease; PET/CT evaluation of cardiac sarcoidosis; PET/MRI in cardiovascular imaging; Evolving role of PET in detecting and characterizing cardiovascular disorders; PET/CT evaluation of infectious diseases of the heart; State of PET-based gating in cardiac imaging; Potential role of PET in assessing cardiac arrhythmias; PET-based cardiovascular imaging tracers; and more!
Author: Federico Caobelli
Author: Federico Caobelli
Author: Elena Aikawa
Author: Wilbert S. Aronow
Author: Hongjun Li
Author: Elena Lazzeri
Author: Georg Wick
Author: Matthieu Pelletier-Galarneau
Author: Reece Joseph Goiffon
Author: Abass Alavi
Author: