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Chemistry in Action: Making Molecular Movies with Ultrafast Electron Diffraction and Data Science

Chemistry in Action: Making Molecular Movies with Ultrafast Electron Diffraction and Data Science PDF Author: Lai Chung Liu
Publisher: Springer Nature
ISBN: 3030548511
Category : Science
Languages : en
Pages : 249

Book Description
The thesis provides the necessary experimental and analytical tools to unambiguously observe the atomically resolved chemical reactions. A great challenge of modern science has been to directly observe atomic motions during structural transitions, and while this was first achieved through a major advance in electron source brightness, the information content was still limited and new methods for image reconstruction using femtosecond electron diffraction methods were needed. One particular challenge lay in reconciling the innumerable possible nuclear configurations with the observation of chemical reaction mechanisms that reproducibly give the same kind of chemistry for large classes of molecules. The author shows that there is a simple solution that occurs during barrier crossing in which the highly anharmonic potential at that point in nuclear rearrangements couples high- and low-frequency vibrational modes to give highly localized nuclear motions, reducing hundreds of potential degrees of freedom to just a few key modes. Specific examples are given in this thesis, including two photoinduced phase transitions in an organic system, a ring closure reaction, and two direct observations of nuclear reorganization driven by spin transitions. The emerging field of structural dynamics promises to change the way we think about the physics of chemistry and this thesis provides tools to make it happen.

Chemistry in Action: Making Molecular Movies with Ultrafast Electron Diffraction and Data Science

Chemistry in Action: Making Molecular Movies with Ultrafast Electron Diffraction and Data Science PDF Author: Lai Chung Liu
Publisher: Springer Nature
ISBN: 3030548511
Category : Science
Languages : en
Pages : 249

Book Description
The thesis provides the necessary experimental and analytical tools to unambiguously observe the atomically resolved chemical reactions. A great challenge of modern science has been to directly observe atomic motions during structural transitions, and while this was first achieved through a major advance in electron source brightness, the information content was still limited and new methods for image reconstruction using femtosecond electron diffraction methods were needed. One particular challenge lay in reconciling the innumerable possible nuclear configurations with the observation of chemical reaction mechanisms that reproducibly give the same kind of chemistry for large classes of molecules. The author shows that there is a simple solution that occurs during barrier crossing in which the highly anharmonic potential at that point in nuclear rearrangements couples high- and low-frequency vibrational modes to give highly localized nuclear motions, reducing hundreds of potential degrees of freedom to just a few key modes. Specific examples are given in this thesis, including two photoinduced phase transitions in an organic system, a ring closure reaction, and two direct observations of nuclear reorganization driven by spin transitions. The emerging field of structural dynamics promises to change the way we think about the physics of chemistry and this thesis provides tools to make it happen.

Bioinformatics and Drug Discovery

Bioinformatics and Drug Discovery PDF Author: Richard S. Larson
Publisher:
ISBN: 9781617799655
Category : Bioinformatics
Languages : en
Pages : 374

Book Description
Recent advances in drug discovery have been rapid. The second edition of Bioinformatics and Drug Discovery has been completely updated to include topics that range from new technologies in target identification, genomic analysis, cheminformatics, protein analysis, and network or pathway analysis. Each chapter provides an extended introduction that describes the theory and application of the technology. In the second part of each chapter, detailed procedures related to the use of these technologies and software have been incorporated. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Bioinformatics and Drug Discovery, Second Edition seeks to aid scientists in the further study of the rapidly expanding field of drug discovery.

Publications of Los Alamos Research

Publications of Los Alamos Research PDF Author: Los Alamos National Laboratory
Publisher:
ISBN:
Category : Research
Languages : en
Pages : 192

Book Description


Tokamaks

Tokamaks PDF Author: John Wesson
Publisher: Oxford University Press
ISBN: 0199592233
Category : Science
Languages : en
Pages : 828

Book Description
The tokamak is the principal tool in controlled fusion research. This book acts as an introduction to the subject and a basic reference for theory, definitions, equations, and experimental results. The fourth edition has been completely revised, describing their development of tokamaks to the point of producing significant fusion power.

Publications of LASL Research

Publications of LASL Research PDF Author: Los Alamos Scientific Laboratory
Publisher:
ISBN:
Category : Research
Languages : en
Pages : 252

Book Description


Forest Inventory

Forest Inventory PDF Author: Annika Kangas
Publisher: Springer Science & Business Media
ISBN: 1402043813
Category : Technology & Engineering
Languages : en
Pages : 368

Book Description
This book has been developed as a forest inventory textbook for students and could also serve as a handbook for practical foresters. We have set out to keep the mathematics in the book at a fairly non-technical level, and therefore, although we deal with many issues that include highly sophisticated methodology, we try to present first and foremost the ideas behind them. For foresters who need more details, references are given to more advanced scientific papers and books in the fields of statistics and biometrics. Forest inventory books deal mostly with sampling and measurement issues, as found here in section I, but since forest inventories in many countries involve much more than this, we have also included material on forestry applications. Most applications nowadays involve remote sensing technology of some sort, so that section II deals mostly with the use of remote sensing material for this purpose. Section III deals with national inventories carried out in different parts of world, and section IV is an attempt to outline some future possibilities of forest inventory methodologies. The editors, Annika Kangas Professor of Forest Mensuration and Management, Department of Forest Resource Management, University of Helsinki. Matti Maltamo Professor of Forest Mensuration, Faculty of Forestry, University of Joensuu. ACKNOWLEDGEMENTS

The Complete Encyclopedia of Terrorist Organisations

The Complete Encyclopedia of Terrorist Organisations PDF Author: Paul Ashley
Publisher:
ISBN: 9781612001180
Category : Terrorism
Languages : en
Pages : 0

Book Description
"Published by arrangement with Frontline Noir, an imprint of Books Noir, Scotland"--T.p. verso.

Annual Report FY...

Annual Report FY... PDF Author: National Institutes of Health (U.S.). Biomedical Engineering and Instrumentation Branch
Publisher:
ISBN:
Category : Biomedical engineering
Languages : en
Pages : 140

Book Description


Intangible Heritage Embodied

Intangible Heritage Embodied PDF Author: D. Fairchild Ruggles
Publisher: Springer Science & Business Media
ISBN: 1441900721
Category : Social Science
Languages : en
Pages : 219

Book Description
Archaeological research has long focused on studying tangible artifacts to build a picture of the cultures it examines. Equally important to understanding a culture, however, are the intangible elements that become part of its heritage. In 2003, UNESCO adopted a convention specifically to protect intangible heritage, including the following: oral traditions and expressions, including language; performing arts (such as traditional music, dance, and theater); social practices, rituals, and festive events; knowledge and practices concerning nature and the universe; and traditional craftsmanship. Since this convention was adopted, scholars and preservationists have struggled with how to best approach intangible heritage. This volume specifically focuses on embodied intangible heritage, or the human body as a vehicle for memory, movement, and sound. The contributors to this work examine ritual and artistic movement, theater, music, oral literature, as well as the role of the internet in cultural transmission. Globalization and particularly the internet, has a complex effect on the transmission of intangible heritage: while music, dance, and other expressions are now shared easily, the performances often lack context and may be shared with a group that does not fully understand what they are seeing or hearing. This volume draws on case studies from around the world to examine the problems and possibilities of implementing the new UNESCO convention. The findings in this volume will be vital to both professionals and academics in anthropology, archaeology, history, museum studies, architecture, and anyone else who deals with issues of cultural heritage and preservation.

Mononuclear Phagocyte Biology

Mononuclear Phagocyte Biology PDF Author: Alvin Volkman
Publisher: Marcel Dekker
ISBN:
Category : Medical
Languages : en
Pages : 536

Book Description