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Author: Publisher: ISBN: Category : Languages : en Pages : 66
Book Description
World-wide, about 200,000 people are hospitalized with Hemorrhagic fever with renal syndrome (HFRS) (3-10% fatality) each year. The etiologic agents of HFRS are Hantaan, Seoul and Puumala viruses of the genus Hantavirus, family Bunyaviridae. A severe form of HFRS, caused by Hantaan virus, occurs in Asia and eastern parts of Europe, a moderate form, caused by Seoul and Seoul- like virus, occurs in Asia, and a mild form, caused by Puumala virus, occurs in Europe. The reservoirs of hantaviruses are rodents and small mammals. Geographical distribution of hantaviruses and-surveillance of HFRS are important for prevention of this highly fatal disease. Little is known about the pathogenesis of HFRS. It is also important to investigate antigenic differences of hantaviruses isolated from non-endemic areas of the world because HFRS patients have never been documented in many areas despite the finding of positive man and rodents there.
Author: Publisher: ISBN: Category : Languages : en Pages : 66
Book Description
World-wide, about 200,000 people are hospitalized with Hemorrhagic fever with renal syndrome (HFRS) (3-10% fatality) each year. The etiologic agents of HFRS are Hantaan, Seoul and Puumala viruses of the genus Hantavirus, family Bunyaviridae. A severe form of HFRS, caused by Hantaan virus, occurs in Asia and eastern parts of Europe, a moderate form, caused by Seoul and Seoul- like virus, occurs in Asia, and a mild form, caused by Puumala virus, occurs in Europe. The reservoirs of hantaviruses are rodents and small mammals. Geographical distribution of hantaviruses and-surveillance of HFRS are important for prevention of this highly fatal disease. Little is known about the pathogenesis of HFRS. It is also important to investigate antigenic differences of hantaviruses isolated from non-endemic areas of the world because HFRS patients have never been documented in many areas despite the finding of positive man and rodents there.
Author: H. W. Lee Publisher: ISBN: Category : Languages : en Pages : 40
Book Description
This report presents the results of seroepidemiologic studies of laboratory infections with Hantaan virus in animal rooms of institutes in Korea and Japan during last 5 years, and isolation of Hantaan virus from urban rats caught in Incheon harbor and Tokyo harbor and, isolation of 7 strains of Hantaan virus from lung tissues of rodent in tissue culture cells. From 1975 to 1981, 126 cases of Hemorrhagic Fever with Renal Syndrome (HFRS), of which one was fatal, had occurred in 22 animal rooms of research laboratories in Korea and Japan. Among colonized laboratory rats of the animal rooms, 71% (Korea) and 40% (Japan) had antibodies to Hantaan virus. In Korea, 23% of those 71% were proven to have pulmonary viral antigen and 7 strains of Hantan virus were isolated from those rats. 203 urban rats caught in Tokyo harbor yielded 5 isolates of Hantaan virus of which one strain was propagated in Vero E-6 cells. 215 urban rats caught in Incheon harbor yielded 14 isolates of Hantaan virus of which one strain was propagated in vero E-6 cells and found to have both of the antigenic characteristics as that of Korean agent and NE agent. Five strains of Hantaan virus were isolated and propagated in Vero E-6 cells; three strains are from blood of HFRS patients and two strains from wild Apodemus mice. Originator supplied keywords include: R. norvegicus. Immunofluorescent antibody technique, Vero E-6 cells, Laboratory infection.
Author: Richard M. Elliott Publisher: Springer Science & Business Media ISBN: 1489913645 Category : Medical Languages : en Pages : 351
Book Description
In this comprehensive reference, leading researchers examine the biology, molecular biology, and diseases of the Bunyaviridae, and provide up-to-date information on the genetic characterization and variations of this virus group. Chapters deal with the molecular biology of five genera: Bunyavirus, Hantavirus, Nairovirus, Phlebovirus, and Tospovirus. Chapters examine Bunyaviridae assembly and intracelluar protein transport as well as Bunyaviridae genetics. Contributors discuss the Bunyaviridae diseases, including the hantavirus pulmonary syndrome.
Author: Publisher: ISBN: Category : Languages : en Pages : 24
Book Description
Studies were conducted throughout Korea to better characterize the distribution of militarily important human infections. Antibodies to hantaviruses were demonstrated in 12-15% of urban and rural civilian adults; antibodies to scrub and murine typhus were detected in 11% and 45%. No antibodies to hepatitis A were detected in 40% of rural males age 20, 35% of ROK Military Academy cadets, and 20% of ROKA recruits surveyed. Examination of serum specimens from civilian and ROK military patients admitted with hemorrhagic manifestations continue to show that HFRS usually accounts for less than half of etiologic diagnoses, and the etiology remains unknown in a substantial portion. Most HFRS disease continues to occur in the fall, however a small number of cases occur throughout the year. Urban transmission of scrub typhus was recognized in rapidly developing areas, suggesting that R tsutsugamushi-infected chigger mites may persist with their rodent hosts in areas where urban development encroaches on former scrub habitat. An extensive geozoological survey found the risk to humans of acquiring a HTNV infection is highest in grassy or scrub areas. Hantavirus, Murine typhus, Scrub typhus, Spotted fever, Leptospirosis, Seroepidemiology, Hepatitis, Geozoological survey.
Author: Institute of Medicine Publisher: National Academies Press ISBN: 0309045487 Category : Medical Languages : en Pages : 112
Book Description
This book contains papers presented at a conference which describe studies of a World War II hepatitis epidemic, a genetic analysis of substance use in veteran twins, hemorrhagic fever with renal syndrome, the psychological effects of military captivity, and dioxin in adipose tissue. Other papers discuss radiation risk studies in military populations and resources for epidemiologic research in Vietnam-era veterans. This volume should be of interest to epidemiologists, medical researchers, and others interested in public health.
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Author: H. W. Lee
Author: Richard M. Elliott
Author: C.H. Calisher
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Author: William Livingston Jellison
Author: Ho Wang Lee
Author: 
Author: Ho Wang Lee
Author: Institute of Medicine