Author: Roger W. Beuerman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 264
Book Description
Healing Processes in the Cornea
Author: Roger W. Beuerman
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 264
Book Description
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 264
Book Description
The process of wound healing in the corneal epithelium
Author: William Marshall Covode
Publisher:
ISBN:
Category :
Languages : en
Pages : 72
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 72
Book Description
Wound Healing of the Ocular Surface
Experimental Corneal Alkali Wound Healing
Author: Jang-Hyun Chung
Publisher:
ISBN:
Category : Alkalies
Languages : en
Pages : 44
Book Description
Publisher:
ISBN:
Category : Alkalies
Languages : en
Pages : 44
Book Description
Biomechanics of Corneal Wound Healing
Author: James Charles Ramier
Publisher:
ISBN:
Category : Biomechanics
Languages : en
Pages : 160
Book Description
"The re-establishment of tissue continuity, function, and mechanical proper ties after a through-and-through incision is an important issue in corneal surgery and trauma. Variations in healing can affect vision and patient activity during the recovery period, which may last up to five years. Growth factors introduced into the open wound have the potential to speed up the wound-healing process. The current investigation is concerned with quantitatively characterizing the mechanical properties of corneal tissue and evaluating the effects of epidermal growth factor (EGF), insulin-like growth factor (IGF), and platelet-derived growth factor (PDGF) on accelerating the wound-healing process as compared to a control group treated with phosphate-buffered saline (PBS). A 30 day topical application period was employed to assess the influence of EGF, IGF, and PDGF versus PBS treated corneas following through-and-through incisions. Corneal test specimens were harvested at 3, 10, and 30 days postoperatively and subjected to uniaxial tension loading (perpendicular to the wound) with load and displacement values recorded. Gross strength properties of fracture toughness, peak tangent modulus, and peak stress were calculated and the stiffness characteristics of the test specimens were obtained through curve fitting of the stress - stretch ratio profile. Comparison of strength properties indicated that IGF application enhanced peak stress, tangent modulus, and fracture toughness at 3 and 10 days while EGF application produced dominant responses at 30 days. Stiffness characterization revealed enhanced stiffness with EGF at 3 and 30 days, while PDGF treatment showed dominant stiffness characteristics at 10 days. The results suggest that select growth factors may preferentially augment the time course of corneal wound healing."--Abstract.
Publisher:
ISBN:
Category : Biomechanics
Languages : en
Pages : 160
Book Description
"The re-establishment of tissue continuity, function, and mechanical proper ties after a through-and-through incision is an important issue in corneal surgery and trauma. Variations in healing can affect vision and patient activity during the recovery period, which may last up to five years. Growth factors introduced into the open wound have the potential to speed up the wound-healing process. The current investigation is concerned with quantitatively characterizing the mechanical properties of corneal tissue and evaluating the effects of epidermal growth factor (EGF), insulin-like growth factor (IGF), and platelet-derived growth factor (PDGF) on accelerating the wound-healing process as compared to a control group treated with phosphate-buffered saline (PBS). A 30 day topical application period was employed to assess the influence of EGF, IGF, and PDGF versus PBS treated corneas following through-and-through incisions. Corneal test specimens were harvested at 3, 10, and 30 days postoperatively and subjected to uniaxial tension loading (perpendicular to the wound) with load and displacement values recorded. Gross strength properties of fracture toughness, peak tangent modulus, and peak stress were calculated and the stiffness characteristics of the test specimens were obtained through curve fitting of the stress - stretch ratio profile. Comparison of strength properties indicated that IGF application enhanced peak stress, tangent modulus, and fracture toughness at 3 and 10 days while EGF application produced dominant responses at 30 days. Stiffness characterization revealed enhanced stiffness with EGF at 3 and 30 days, while PDGF treatment showed dominant stiffness characteristics at 10 days. The results suggest that select growth factors may preferentially augment the time course of corneal wound healing."--Abstract.
Corneal Emergencies
Author: Bhavana Sharma
Publisher: Springer Nature
ISBN: 9811658765
Category : Medical
Languages : en
Pages : 405
Book Description
The book provides a comprehensive insight into various corneal emergencies along with their risk factors, causative agents, diagnostic pearls, treatment challenges and management options. It provides essential information on relevant anatomical and physiological aspects in addition to epidemiology and risk factors. Comprising of explanatory flow diagrams, diagnostic and treatment algorithms and high-quality illustrations, this book is written and edited by renowned corneal specialists who have come together to address this complex topic in a simple and effective manner. The book highlights an important aspect of cornea which is relevant for specialists and general ophthalmologists alike and also serves as an important resource for postgraduate students and trainees. It emphasizes on the practical management of corneal emergencies, supplemented with preferred practice patterns and guidelines. Additionally, the book serves as a quick reference for ophthalmic practitioners to adequately manage such cases at the point of first contact.
Publisher: Springer Nature
ISBN: 9811658765
Category : Medical
Languages : en
Pages : 405
Book Description
The book provides a comprehensive insight into various corneal emergencies along with their risk factors, causative agents, diagnostic pearls, treatment challenges and management options. It provides essential information on relevant anatomical and physiological aspects in addition to epidemiology and risk factors. Comprising of explanatory flow diagrams, diagnostic and treatment algorithms and high-quality illustrations, this book is written and edited by renowned corneal specialists who have come together to address this complex topic in a simple and effective manner. The book highlights an important aspect of cornea which is relevant for specialists and general ophthalmologists alike and also serves as an important resource for postgraduate students and trainees. It emphasizes on the practical management of corneal emergencies, supplemented with preferred practice patterns and guidelines. Additionally, the book serves as a quick reference for ophthalmic practitioners to adequately manage such cases at the point of first contact.
Neuropeptides and Neurotransmitters in Keratocytes
The Iris
Author: Kambiz Thomas Moazed
Publisher: Springer Nature
ISBN: 3030457567
Category : Medical
Languages : en
Pages : 257
Book Description
The iris is a circular, pigmented tissue that separates the anterior chamber of the eye from the posterior chamber. It has a crucial role on controlling the amount of the light entering the eye through its central opening “the pupil". The Iris has multiple important functions that support and provide image clarity on the retina. However, it is a largely neglected part of the eye, compared to the cornea lens, retina, and optic nerve, and has not been focused on in a comprehensive way until now. The Iris: Understanding the Essentials, combines different aspects of scientific information from a variety of fields, such as anatomy, histopathology, molecular biology, electron microscopy and other diagnostic modalities. Each chapter will include pearls and summary points, and this multi-disciplinary approach helps the clinician diagnose and treat the large variety of diseases that affect the iris, with the main emphasize on pigmentary pathological changes that can affect the color of the eye. Written as a reference review book for universities, practicing ophthalmologists, Ophthalmology residents, pharmaceutical companies and diagnostic equipment manufacturing companies this book summarizes the information in an easy-to-use manner to help the reader better understand the iris, iris structure, physiology and function.
Publisher: Springer Nature
ISBN: 3030457567
Category : Medical
Languages : en
Pages : 257
Book Description
The iris is a circular, pigmented tissue that separates the anterior chamber of the eye from the posterior chamber. It has a crucial role on controlling the amount of the light entering the eye through its central opening “the pupil". The Iris has multiple important functions that support and provide image clarity on the retina. However, it is a largely neglected part of the eye, compared to the cornea lens, retina, and optic nerve, and has not been focused on in a comprehensive way until now. The Iris: Understanding the Essentials, combines different aspects of scientific information from a variety of fields, such as anatomy, histopathology, molecular biology, electron microscopy and other diagnostic modalities. Each chapter will include pearls and summary points, and this multi-disciplinary approach helps the clinician diagnose and treat the large variety of diseases that affect the iris, with the main emphasize on pigmentary pathological changes that can affect the color of the eye. Written as a reference review book for universities, practicing ophthalmologists, Ophthalmology residents, pharmaceutical companies and diagnostic equipment manufacturing companies this book summarizes the information in an easy-to-use manner to help the reader better understand the iris, iris structure, physiology and function.
Ocular Transporters and Receptors
Author: Ashim K Mitra
Publisher: Elsevier
ISBN: 190881831X
Category : Science
Languages : en
Pages : 276
Book Description
Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. Highly focused on ocular transporters Most up-to-date research compilation Detailed description of role of transporters and receptors in ocular drug discovery and delivery
Publisher: Elsevier
ISBN: 190881831X
Category : Science
Languages : en
Pages : 276
Book Description
Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. Highly focused on ocular transporters Most up-to-date research compilation Detailed description of role of transporters and receptors in ocular drug discovery and delivery