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Author: Robert Helms Publisher: Garrett County Press ISBN: 1891053280 Category : Biography & Autobiography Languages : en Pages : 270
Book Description
From first person accounts of pharmaceutical studies gone bad to intricate medical histories, Guinea Pig Zero provides a fascinating look at the people who sell their bodies to science. While the book provides advice to present-day research subjects (by rating research clinics), the book also provides context by investigating the history and ethics behind this important, but little-known medical industry.
Author: Robert Helms Publisher: Garrett County Press ISBN: 1891053280 Category : Biography & Autobiography Languages : en Pages : 270
Book Description
From first person accounts of pharmaceutical studies gone bad to intricate medical histories, Guinea Pig Zero provides a fascinating look at the people who sell their bodies to science. While the book provides advice to present-day research subjects (by rating research clinics), the book also provides context by investigating the history and ethics behind this important, but little-known medical industry.
Author: Roberto Abadie Publisher: Duke University Press ISBN: 0822393247 Category : Social Science Languages : en Pages : 199
Book Description
The Professional Guinea Pig documents the emergence of the professional research subject in Phase I clinical trials testing the safety of drugs in development. Until the mid-1970s Phase I trials were conducted on prisoners. After that practice was outlawed, the pharmaceutical industry needed a replacement population and began to aggressively recruit healthy, paid subjects, some of whom came to depend on the income, earning their living by continuously taking part in these trials. Drawing on ethnographic research among self-identified “professional guinea pigs” in Philadelphia, Roberto Abadie examines their experiences and views on the conduct of the trials and the risks they assume by participating. Some of the research subjects he met had taken part in more than eighty Phase I trials. While the professional guinea pigs tended to believe that most clinical trials pose only a moderate health risk, Abadie contends that the hazards presented by continuous participation, such as exposure to potentially dangerous drug interactions, are discounted or ignored by research subjects in need of money. The risks to professional guinea pigs are also disregarded by the pharmaceutical industry, which has become dependent on the routine participation of experienced research subjects. Arguing that financial incentives compromise the ethical imperative for informed consent to be freely given by clinical-trials subjects, Abadie confirms the need to reform policies regulating the participation of paid subjects in Phase I clinical trials.
Author: Margery Cuyler Publisher: Walker Childrens ISBN: 9780802797957 Category : Juvenile Fiction Languages : en Pages : 0
Book Description
In bouncy, appealing rhyme, young readers are introduced to a classroom with a hairy problem-guinea pigs that keep adding and adding! From one lonely guinea pig to two to five and all the way up to twenty, the kids find that having a classroom pet is more than they bargained for. Finally, each student gets to take a guinea pig home, until they are left with zero. That is, until Mr. Gilbert brings in a rabbit with a growing belly . . . ! From master storyteller Margery Cuyler and with energetic illustrations from Tracey Campbell Pearson, Guinea Pigs Add Up is perfect for budding mathematicians-or anyone with a love for unruly animals.
Author: Rebecca Dresser Publisher: Oxford University Press ISBN: 0190459271 Category : Medical Languages : en Pages : 321
Book Description
The research ethics system was created without the help of people who know what it is like to be a research subject. This is a serious omission. Experts have overlooked ethical issues that matter to subjects. Silent Partners moves subjects to the forefront, giving them a voice in research ethics.
Author: Eileen Welsome Publisher: Delta ISBN: 0307767337 Category : History Languages : en Pages : 724
Book Description
When the vast wartime factories of the Manhattan Project began producing plutonium in quantities never before seen on earth, scientists working on the top-secret bomb-building program grew apprehensive. Fearful that plutonium might cause a cancer epidemic among workers and desperate to learn more about what it could do to the human body, the Manhattan Project's medical doctors embarked upon an experiment in which eighteen unsuspecting patients in hospital wards throughout the country were secretly injected with the cancer-causing substance. Most of these patients would go to their graves without ever knowing what had been done to them. Now, in The Plutonium Files, Pulitzer Prize-winning reporter Eileen Welsome reveals for the first time the breadth of the extraordinary fifty-year cover-up surrounding the plutonium injections, as well as the deceitful nature of thousands of other experiments conducted on American citizens in the postwar years. Welsome's remarkable investigation spans the 1930s to the 1990s and draws upon hundreds of newly declassified documents and other primary sources to disclose this shadowy chapter in American history. She gives a voice to such innocents as Helen Hutchison, a young woman who entered a prenatal clinic in Nashville for a routine checkup and was instead given a radioactive "cocktail" to drink; Gordon Shattuck, one of several boys at a state school for the developmentally disabled in Massachusetts who was fed radioactive oatmeal for breakfast; and Maude Jacobs, a Cincinnati woman suffering from cancer and subjected to an experimental radiation treatment designed to help military planners learn how to win a nuclear war. Welsome also tells the stories of the scientists themselves, many of whom learned the ways of secrecy on the Manhattan Project. Among them are Stafford Warren, a grand figure whose bravado masked a cunning intelligence; Joseph Hamilton, who felt he was immune to the dangers of radiation only to suffer later from a fatal leukemia; and physician Louis Hempelmann, one of the most enthusiastic supporters of the plan to inject humans with potentially carcinogenic doses of plutonium. Hidden discussions of fifty years past are reconstructed here, wherein trusted government officials debated the ethical and legal implications of the experiments, demolishing forever the argument that these studies took place in a less enlightened era. Powered by her groundbreaking reportage and singular narrative gifts, Eileen Welsome has created a work of profound humanity as well as major historical significance. From the Hardcover edition.
Author: Sonia Shah Publisher: New Press, The ISBN: 1595588310 Category : Medical Languages : en Pages : 257
Book Description
Hailed by John le Carré as “an act of courage on the part of its author” and singled out for praise by the leading medical journals in the United States and the United Kingdom, The Body Hunters uncovers the real-life story behind le Carré's acclaimed novel The Constant Gardener and the feature film based on it. "A trenchant exposé . . . meticulously researched and packed with documentary evidence" (Publishers Weekly), Sonia Shah's riveting journalistic account shines a much-needed spotlight on a disturbing new global trend. Drawing on years of original research and reporting in Africa and Asia, Shah examines how the multinational pharmaceutical industry, in its quest to develop lucrative drugs, has begun exporting its clinical research trials to the developing world, where ethical oversight is minimal and desperate patients abound. As the New England Journal of Medicine notes, “it is critical that those engaged in drug development, clinical research and its oversight, research ethics, and policy know about these stories,” which tell of an impossible choice being faced by many of the world's poorest patients—be experimented upon or die for lack of medicine.
Author: Carl Elliott Publisher: Beacon Press ISBN: 0807061441 Category : Medical Languages : en Pages : 233
Book Description
By New Yorker and Atlantic writer Carl Elliott, a readable and even funny account of the serious business of medicine. A tongue-in-cheek account of the changes that have transformed medicine into big business. Physician and medical ethicist Carl Elliott tracks the new world of commercialized medicine from start to finish, introducing the professional guinea pigs, ghostwriters, thought leaders, drug reps, public relations pros, and even medical ethicists who use medicine for (sometimes huge) financial gain. Along the way, he uncovers the cost to patients lost in a health-care universe centered around consumerism.
Author: Osagie K. Obasogie Publisher: Univ of California Press ISBN: 0520961943 Category : Social Science Languages : en Pages : 547
Book Description
For decades, the field of bioethics has shaped the way we think about ethical problems in science, technology, and medicine. But its traditional emphasis on individual interests such as doctor-patient relationships, informed consent, and personal autonomy is minimally helpful in confronting the social and political challenges posed by new human biotechnologies such as assisted reproduction, human genetic modification, and DNA forensics. Beyond Bioethics addresses these provocative issues from an emerging standpoint that is attentive to race, gender, class, disability, privacy, and notions of democracy—a "new biopolitics." This authoritative volume provides an overview for those grappling with the profound dilemmas posed by these developments. It brings together the work of cutting-edge thinkers from diverse fields of study and public engagement, all of them committed to this new perspective grounded in social justice and public interest values.
Author: Richard K. Miller Publisher: Springer Science & Business Media ISBN: 1468411918 Category : Medical Languages : en Pages : 380
Book Description
Each year since 1961, the Rochester Trophoblast Conference has grown in the diversity of its approaches to trophoblast research. At the Ninth Conference, Professors Klopper, Villee and Winick molded the conference with their state of the art addresses on Endocrinology, Metabolism and Nutrition of the Trophoblast. The Conference was favored with a multitude of creative studies and with warm, sunny, autumn weather to discuss these results. In October of 1982, one hundred and five investigators from 12 countries and 21 states discussed 42 different presentations at the Holiday Inn in Rochester, New York. The Ninth Conference introduced workshops on Metabolism, Nutrition, Endocrinology and Trophoblastic Neoplasia. The chairmen of these workshops were: Metabolism -Villee and Miller; Nutrition - Winick and Maulik; Endocrinology - Klopper and Muechler; and Trophoblastic Neoplasia -Szulman and Helmkamp. These two-hour, intimate discussion groups were well-received by all who attended. As with the Eighth Conference, the University of Rochester will no longer produce a transcript of the Conference. Beginning with the Ninth Conference, Plenum Press in association with the University, will publish a peer-reviewed series entitled Trophoblast Research. An international editorial advisory board has been named to assure the direction of the series. The editorial board and the organizing committee will develop the future meetings of the Rochester Trophoblast Conference. Trophoblast Research will be published as single bound volumes with original contributions and editorial reports of presentations from the Conference.
Author: Robert Helms
Author: Robert Helms
Author: Roberto Abadie
Author: Margery Cuyler
Author: Rebecca Dresser
Author: Eileen Welsome
Author: Sonia Shah
Author: Carl Elliott
Author: Osagie K. Obasogie
Author: 
Author: Richard K. Miller