Genetic Analysis of Quantitative Traits Using Domestic Animals PDF Download

Author: Hee-Bok Park
Publisher:
ISBN: 9789155460563
Category :
Languages : en
Pages : 51

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Author: Joel Ira Weller
Publisher: CABI
ISBN: 1845937341
Category : Technology & Engineering
Languages : en
Pages : 288

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Book Description
Quantitative Trait Loci (QTL) is a topic of major agricultural significance for efficient livestock production. This book covers various statistical methods that have been used or proposed for detection and analysis of QTL and marker-and gene-assisted selection in animal genetics and breeding.

Author: Michael Lynch
Publisher: Sinauer Associates Incorporated
ISBN: 9780878934812
Category : Science
Languages : en
Pages : 980

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Book Description
Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.

Author: Anne Charmantier
Publisher: Oxford University Press
ISBN: 019967423X
Category : Medical
Languages : en
Pages : 293

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Book Description
This book gathers the expertise of 30 evolutionary biologists from around the globe to highlight how applying the field of quantitative genetics - the analysis of the genetic basis of complex traits - aids in the study of wild populations.

Author: Hasan Khatib
Publisher: John Wiley & Sons
ISBN: 1118677404
Category : Science
Languages : en
Pages : 336

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Book Description
Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.

Author: D.C. Rao
Publisher: Academic Press
ISBN: 0080569110
Category : Medical
Languages : en
Pages : 788

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Book Description
The field of genetics is rapidly evolving and new medical breakthroughs are occuring as a result of advances in knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines. Five sections on the latest advances in complex traits Methods for testing with ethical, legal, and social implications Hot topics include discussions on systems biology approach to drug discovery; using comparative genomics for detecting human disease genes; computationally intensive challenges, and more

Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 328

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Book Description
This dissertation deals with the genetic analysis of complex traits in livestock species. The first part focuses on the analysis of bull fertility with the aim of finding and characterizing genomic regions responsible for the genetic variation in this trait in cattle. Two complementary studies were performed, namely a genome-wide association study and a subsequent quantitative trait pathway-based analysis. These studies identified genomic regions, and particularly individual genes and pathways that showed significant effects on bull fertility. These findings contribute to a better understanding of the genetics underlying this complex traits in cattle, as well as provide opportunities for changing fertility by means of selective breeding. The second part of this thesis tackles the effect of maternal nutrition on the epigenome of the offspring in order to understand the genetic mechanisms underlying fetal programing in livestock. In particular, the effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos, and the impact of different maternal diets on the transcriptome of fetal tissues in sheep were investigated. These studies provided evidence that maternal diet can indeed modulate gene expression in the offspring. Determination of gene expression changes could foreshadow potential effects of maternal diets on the future development of offspring, such as postnatal growth, production, health, and reproductive performance. The last part of this thesis evaluates the inference of causal networks in multivariate genetic systems. In particular, the inference of causal networks including latent variables in a quantitative genetics context, and the reconstruction of gene-phenotype networks integrating multi-omics data were investigated. Both procedures were applied to pig data to unravel the mechanisms underlying the antagonist relationship between growth and meat lean content with fat deposition and product quality. More generally, the proposed methods provide useful analytical tools to further learning about phenotypic and molecular causal structures underlying complex traits in farm species

Author: Per Jensen
Publisher: Elsevier Inc. Chapters
ISBN: 0128059931
Category : Medical
Languages : en
Pages : 46

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Book Description
In this chapter, we begin by defining domestication as a genetic process, whereby animals change phenotypically and genetically as a response to living under human supervision. This has caused a convergent set of phenotypic modifications across numerous different species, through a combination of relaxed natural selection, increased human selection, and correlated responses. The genetic mechanisms underlying these processes are discussed in addition to genetic drift and inbreeding. The driving types of mutations are dealt with, as is the way in which genes are organized in the genome to give rise to a specific genetic architecture facilitating selection responses. The different methods used to discover genes and mutations are divided into either top-down approaches, where one starts with the phenotype and uses mapping methods to find the causative genes, or bottom-up, where the genetic polymorphism is the starting point and the phenotype the desired response variable. A number of examples of single genes and mutations that have been coupled to behavioral variation are given, among them genes showing pleiotropic effects on pigmentation, and genes involved in regulation of the effects of neuropeptides. Finally, the relatively novel area of behavioral epigenetics is examined, in particular with its possible relation to domestication effects.

Author: Noelle E. Cockett
Publisher: Springer Science & Business Media
ISBN: 3540738355
Category : Science
Languages : en
Pages : 289

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Book Description
Genomics research on animals has generated huge databases and several new concepts and strategies, which are used to elucidate origin, evolution and phylogeny of species. Genetic and physical maps of genomes give details on chromosomal location, function, expression and regulation of genes. The series Genome Mapping and Genomics in Animals provides comprehensive and up-to-date reviews on genomic research on selected animal systems contributed by leading scientists from around the world. This volume offers information on gene mapping and genomics research in domesticated and farmed animals including cattle, water buffalo, sheep, deer, poultry, turkeys, rabbits, dogs and pigs. While the genome maps for some species are very limited, full genome sequences are available for cattle, chickens and dogs. Genomic research contributes to the identification of genetic regions that control the functionality and well-being of animals. Several farmed species are also used as models for biomedical studies.

Author: National Academy of Sciences
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 388

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Book Description
The Arthur M. Sackler Colloquia of the National Academy of Sciences address scientific topics of broad and current interest, cutting across the boundaries of traditional disciplines. Each year, four or five such colloquia are scheduled, typically two days in length and international in scope. Colloquia are organized by a member of the Academy, often with the assistance of an organizing committee, and feature presentations by leading scientists in the field and discussions with a hundred or more researchers with an interest in the topic. Colloquia presentations are recorded and posted on the National Academy of Sciences Sackler colloquia website and published on CD-ROM. These Colloquia are made possible by a generous gift from Mrs. Jill Sackler, in memory of her husband, Arthur M. Sackler.