Future Directions and Applications in Photodynamic Therapy PDF Download

Author:
Publisher:
ISBN: 9781510610644
Category :
Languages : en
Pages :

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Author: Charles J. Gomer
Publisher: Society of Photo Optical
ISBN: 9780819402301
Category : Medical
Languages : en
Pages : 281

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Book Description

Author: Charles J. Gomer
Publisher: SPIE-International Society for Optical Engineering
ISBN:
Category : Medical
Languages : en
Pages : 312

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Book Description

Author: Flora Fitzgerald
Publisher: Nova Biomedical Books
ISBN: 9781536119121
Category : Photochemotherapy
Languages : en
Pages : 0

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Book Description
As a new concept of cancer treatment, photodynamic therapy (PDT) has gained great attention in the last few decades. Compared to classical treatments such as surgery, chemotherapy and radiotherapy, PDT is a noninvasive, localized treatment of lesions that shows fewer side effects and has low systemic toxicity. In Chapter One, the basic mechanisms, applications and functional nanomaterials-based drug delivery systems for photodynamic therapy of cancer are reviewed. Chapter Two summarizes the application of different carbon based nanomaterials as agents for PDT and discusses current state-of-the-art use of fullerenes and their derivatives, carbon nanotubes and graphene quantum dots in PDT. Chapter Three covers the benefits and pitfalls of using chemi- and bioluminescent systems as intracellular excitation sources in PDT. Bioluminescence is a widespread natural phenomenon, which consists on emission of light resulting from the oxidation of a substrate in a reaction catalyzed by an enzyme in a biological system. Chapter Four addresses in the synthesis, characterization, and photodynamic activity of a novel hydrophobic photosensitizer 5,10,15,20-tetrakis(benzo[b]thiophene) Porphyrin (BTP) and water soluble photosensitizer 5,10,15,20-Tetrakis(7- sulfonatobenzo[b]thiophene) Porphyrin (SBTP). The authors lab is engaged in the synthesis of PDT molecules incorporating benzothiophene moiety to the meso-position of porphyrin molecules. Chapter Five discusses the Guidelines for Gastroenterological Endoscopy in Patients on Oral Antithrombotic Treatment established by the Japan Gastroenterological Endoscopy Society (JGES).These guidelines classify endoscopic interventions according to the risk of hemorrhage and specify the management of various antithrombotic drugs. Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are classified as high-risk procedures for hemorrhage, but PDT is not included in the guidelines. Because PDT causes ischemic necrosis of tumor tissue, the authors say this could possibly be performed safely in patients on oral antithrombotic therapy. The authors of Chapter Six developed a method of the initial concentration of protoporphyrin-IX in the operated removing glioblastoma tissue using the calibration curve of the fluorescent intensity and the known Pp-IX concentration in order to estimate of the more correlated with the cure rate.

Author: Thierry Patrice
Publisher: Royal Society of Chemistry
ISBN: 1847551653
Category : Medical
Languages : en
Pages : 292

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Book Description
For centuries, light has been used to cure various diseases. However, it is only recently that a new medical field has arisen. Photodynamic therapy (PDT), also known as photochemotherapy, is a fast growing technique which was initially devoted to cancer care but which is now recognised as a promising treatment technique in a variety of clinical fields. Written by recognised experts, Photodynamic Therapy provides a comprehensive explanation of what PDT is and how it has developed as a technique in areas such as the detection of lung cancer and applications in dermatology, gynaecology and neurosurgery. This book is ideal both as an introduction to PDT and as an informative text for those wishing to expand their knowledge. Practitioners in biological sciences, biotechnology and medicinal and pharmaceutical chemistry will find it an invaluable source of information.

Author: Mahmoud H. Abdel-Kader
Publisher: Springer Science & Business Media
ISBN: 3642396291
Category : Science
Languages : en
Pages : 317

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Book Description
Photodynamic Therapy: From Theory to Application brings attention to an exceptional treatment strategy, which until now has not achieved the recognition and breadth of applications it deserves. The authors, all experts and pioneers in their field, discuss the history and basic principles of PDT, as well as the fundamentals of the theory, methods, and instrumentation of clinical diagnosis and treatment of cancer. Non-oncological applications such as the use of PDT in control of parasites and noxious insects are also discussed. This book serves as a standard reference for researchers and students at all levels, clinical specialists interested in the topic and those in industry exploring new areas for development. A comprehensive exposition of both the theory and application of PDT, this book fills the gaps in the current literature by bringing together both basic understanding of the process of PDT and an expanded vision of its applications.

Author: Mohamed Lotfy Taha Elsaie
Publisher: Nova Science Publishers
ISBN: 9781624176357
Category : Cancer
Languages : en
Pages : 0

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Book Description
"Photodynamic therapy (PDT) is currently clinically employed to treat several malignant and nonmalignant diseases. With approvals for various applications by health agencies in Europe, the US, Canada, and Japan, PDT represents the method of choice for treatment of age-related macular degeneration and is appreciated as a minimally invasive therapeutic procedure to treat skin, esophageal, head and neck, lung, and bladder cancers with high cure rates, nearly no side effects, and excellent cosmetic outcomes. Current basic research and clinical studies will help to further integrate PDT as a mainstream procedure for cancer treatment. This book presents an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases."--

Author: Charles J. Gomer
Publisher: Humana Press
ISBN: 9781607616986
Category : Science
Languages : en
Pages : 294

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Book Description
Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970’s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.

Author: Mohamed Lotfy Taha Elsaie
Publisher:
ISBN: 9781624176609
Category : Health & Fitness
Languages : en
Pages : 287

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Book Description
Photodynamic therapy (PDT) is currently clinically employed to treat several malignant and nonmalignant diseases. With approvals for various applications by health agencies in Europe, the US, Canada, and Japan, PDT represents the method of choice for treatment of age-related macular degeneration and is appreciated as a minimally invasive therapeutic procedure to treat skin, esophageal, head and neck, lung, and bladder cancers with high cure rates, nearly no side effects, and excellent cosmetic outcomes. Current basic research and clinical studies will help to further integrate PDT as a mainstream procedure for cancer treatment. This book presents an overview of the important medical applications of PDT, including approved treatments, clinical trials, and investigated therapies for cancer and non-malignant diseases.

Author: Fábio Parra Sellera
Publisher: Springer
ISBN: 3319450077
Category : Medical
Languages : en
Pages : 233

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Book Description
This pioneering book offers an introduction to photodynamic therapy, a promising new approach in the treatment of complex diseases like cancer and microbial infections in animals. Addressing all aspects, ranging from basics to clinical practice, it presents the history and fundamentals of photodynamic therapy for non-experts. It includes a collection of basic and clinical studies in cancer and infectious diseases, as well as illustrations of successful treatment procedures and future perspectives and innovative applications involving nanotechnology and advanced drug delivery. This valuable resource offers readers insights into how the therapy works and how to apply it effectively in daily practice.