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Author: N. Simpson Publisher: IOS Press ISBN: 9781586034207 Category : Medical Languages : en Pages : 126
Book Description
This is the second part which highlights the role that various imaging techniques play and/or might be able to play in detecting markers of disease. Cancer is often used as the example disease, but tumors exhibit many properties in common with other tissue, so it is possible to see how the techniques could be used in the diagnosis and management of other disease. There are also examples of the reverse of this flow of hypothesis and knowledge from one discipline to another. Magnetic resonance spectroscopy can be used to detect the chemical milieu of the nucleus being focused on, be it phosphorus-31 (Arias-Mendoza) or protons (He). Phosphorus is intimately involved in carbohydrate, phospholipid metabolism and energy transfer. The brain has been the testing ground for ideas in MRI and MRS; it continues to be so today, with extension to tumor diagnosis as insights are reached and assimilated. This issue contains three techniques that rely solely or partially on optical characteristics of tissue. The supplement, in 2 issues, has mostly emphasized possibilities rather than clinically available techniques.The final chapter attempts to draw together the modalities of medical imaging and push the frontiers yet further to show how imaging and markers can be used together in the screening, diagnosis, and management of patients' disease.
Author: N. Simpson Publisher: IOS Press ISBN: 9781586034207 Category : Medical Languages : en Pages : 126
Book Description
This is the second part which highlights the role that various imaging techniques play and/or might be able to play in detecting markers of disease. Cancer is often used as the example disease, but tumors exhibit many properties in common with other tissue, so it is possible to see how the techniques could be used in the diagnosis and management of other disease. There are also examples of the reverse of this flow of hypothesis and knowledge from one discipline to another. Magnetic resonance spectroscopy can be used to detect the chemical milieu of the nucleus being focused on, be it phosphorus-31 (Arias-Mendoza) or protons (He). Phosphorus is intimately involved in carbohydrate, phospholipid metabolism and energy transfer. The brain has been the testing ground for ideas in MRI and MRS; it continues to be so today, with extension to tumor diagnosis as insights are reached and assimilated. This issue contains three techniques that rely solely or partially on optical characteristics of tissue. The supplement, in 2 issues, has mostly emphasized possibilities rather than clinically available techniques.The final chapter attempts to draw together the modalities of medical imaging and push the frontiers yet further to show how imaging and markers can be used together in the screening, diagnosis, and management of patients' disease.
Author: Michelle Hampson Publisher: Academic Press ISBN: 0128224363 Category : Computers Languages : en Pages : 366
Book Description
fMRI Neurofeedback provides a perspective on how the field of functional magnetic resonance imaging (fMRI) neurofeedback has evolved, an introduction to state-of-the-art methods used for fMRI neurofeedback, a review of published neuroscientific and clinical applications, and a discussion of relevant ethical considerations. It gives a view of the ongoing research challenges throughout and provides guidance for researchers new to the field on the practical implementation and design of fMRI neurofeedback protocols. This book is designed to be accessible to all scientists and clinicians interested in conducting fMRI neurofeedback research, addressing the variety of different knowledge gaps that readers may have given their varied backgrounds and avoiding field-specific jargon. The book, therefore, will be suitable for engineers, computer scientists, neuroscientists, psychologists, and physicians working in fMRI neurofeedback. - Provides a reference on fMRI neurofeedback covering history, methods, mechanisms, clinical applications, and basic research, as well as ethical considerations - Offers contributions from international experts—leading research groups are represented, including from Europe, Japan, Israel, and the United States - Includes coverage of data analytic methods, study design, neuroscience mechanisms, and clinical considerations - Presents a perspective on future translational development
Author: David Borsook Publisher: Oxford University Press, USA ISBN: 019975456X Category : Health & Fitness Languages : en Pages : 400
Book Description
The Migraine Brain provides a general overview of the history of migraine, its pathophysiology, as well as in-depth details on the Clinical Perspectives and the different imaging techniques in use (MR, fMRI, DTI, VBM, PET, fMRI, and MEG). It also includes details on modulation of the brain using such techniques as TMS. The book concludes with a discussion of future uses of imaging in the diagnosis and treatment of migraines and other headaches.
Author: Matt A. Bernstein Publisher: Elsevier ISBN: 0080533124 Category : Mathematics Languages : en Pages : 1041
Book Description
Magnetic Resonance Imaging (MRI) is among the most important medical imaging techniques available today. There is an installed base of approximately 15,000 MRI scanners worldwide. Each of these scanners is capable of running many different "pulse sequences", which are governed by physics and engineering principles, and implemented by software programs that control the MRI hardware. To utilize an MRI scanner to the fullest extent, a conceptual understanding of its pulse sequences is crucial. Handbook of MRI Pulse Sequences offers a complete guide that can help the scientists, engineers, clinicians, and technologists in the field of MRI understand and better employ their scanner. - Explains pulse sequences, their components, and the associated image reconstruction methods commonly used in MRI - Provides self-contained sections for individual techniques - Can be used as a quick reference guide or as a resource for deeper study - Includes both non-mathematical and mathematical descriptions - Contains numerous figures, tables, references, and worked example problems
Author: Philip Seeman Publisher: Elsevier ISBN: 012418684X Category : Science Languages : en Pages : 534
Book Description
Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. - A focused introduction to imaging healthy and diseased brains - Focuses on the primary neurotransmitter release - Includes sigma, acetylcholine, opioid, and dopamine receptors - Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease
Author: National Research Council Publisher: National Academies Press ISBN: 0309134153 Category : Medical Languages : en Pages : 173
Book Description
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Author: National Research Council Publisher: National Academies Press ISBN: 0309183952 Category : Medical Languages : en Pages : 24
Book Description
In November 1999, the Institute of Medicine, in consultation with the Commission on Life Sciences, the Commission on Physical Sciences, Mathematics, and Applications, and the Board on Science, Technology and Economic Policy launched a one year study on technologies for early detection of breast cancer. The committee was asked to examine technologies under development for early breast cancer detection, and to scrutinize the process of medical technology development, adoption, and dissemination. The committee is gathering information on these topics for its report in a number of ways, including two public workshops that bring in outside expertise. The first workshop on "Developing Technologies for Early Breast Cancer Detection" was held in Washington DC in February 2000. The content of the presentations at the workshop is summarized here. A second workshop, which will focus on the process of technology development and adoption, will be held in Washington, DC on June 19-20. A formal report on these topics, including conclusions and recommendations, will be prepared by the committee upon completion of the one-year study.
Author: Daniel Laskowitz Publisher: CRC Press ISBN: 1498766579 Category : Medical Languages : en Pages : 388
Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Author: Dan Silverman Publisher: Springer Science & Business Media ISBN: 0387764208 Category : Medical Languages : en Pages : 221
Book Description
Among all the clinical indications for which radiologists, nuclear medicine phy- cians, neurologists, neurosurgeons, psychiatrists (and others examining disorders of the brain) order and read brain PET scans, demand is greatest for those pertaining to dementia and related disorders. This demand is driven by the sheer prevalence of those conditions, coupled with the fact that the differential diagnosis for causes of cognitive impairment is wide and often difficult to distinguish clinically. The conceptual framework by which evaluation and management of dementia is guided has evolved considerably during the last decade. Although we still are far from having ideal tests or dramatic cures for any of the established causes of dementia, our options have expanded with respect to both the diagnostic and the- peutic tools now available. In the first chapter of this book, the contribution and limitations of different elements of the clinical examination for diagnosis of cog- tive symptoms are described, and the roles of structural and functional neuroim- ing in the clinical workup are given context.
Author: Udo Rüb Publisher: Springer ISBN: 331919285X Category : Medical Languages : en Pages : 154
Book Description
This monograph describes the progress in neuropathological HD research made during the last century, the neuropathological hallmarks of HD and their pathogenic relevance. Starting with the initial descriptions of the progressive degeneration of the striatum as one of the key events in HD, the worldwide practiced Vonsattel HD grading system of striatal neurodegeneration will be outlined. Correlating neuropathological data with results on the functional neuroanatomy of the human brain, subsequent chapters will highlight recent HD findings: the neuronal loss in the cerebral neo-and allocortex, the neurodegeneration of select thalamic nuclei, the affection of the cerebellar cortex and nuclei, the involvement of select brainstem nuclei, as well as the pathophysiological relevance of these pathologies for the clinical picture of HD. Finally, the potential pathophysiological role of neuronal huntingtin aggregations and the most important and enduring challenges of neuropathological HD research are discussed.
Author: N. Simpson
Author: N. Simpson
Author: Michelle Hampson
Author: David Borsook
Author: Matt A. Bernstein
Author: Philip Seeman
Author: National Research Council
Author: National Research Council
Author: Daniel Laskowitz
Author: Dan Silverman
Author: Udo Rüb