Author: Robert J. Asher
Publisher: Cambridge University Press
ISBN: 1107003261
Category : Medical
Languages : en
Pages : 399
Book Description
Top researchers show how molecular biology can inform paleontology, directly and indirectly, to better understand life's past.
From Clone to Bone
Author: Robert J. Asher
Publisher: Cambridge University Press
ISBN: 1107003261
Category : Medical
Languages : en
Pages : 399
Book Description
Top researchers show how molecular biology can inform paleontology, directly and indirectly, to better understand life's past.
Publisher: Cambridge University Press
ISBN: 1107003261
Category : Medical
Languages : en
Pages : 399
Book Description
Top researchers show how molecular biology can inform paleontology, directly and indirectly, to better understand life's past.
How to Clone a Mammoth
Author: Beth Shapiro
Publisher: Princeton University Press
ISBN: 0691209561
Category : Nature
Languages : en
Pages : 240
Book Description
An insider's view on bringing extinct species back to life Could extinct species, like mammoths and passenger pigeons, be brought back to life? In How to Clone a Mammoth, Beth Shapiro, an evolutionary biologist and pioneer in ancient DNA research, addresses this intriguing question by walking readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used to resurrect the past. Considering de-extinction's practical benefits and ethical challenges, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.
Publisher: Princeton University Press
ISBN: 0691209561
Category : Nature
Languages : en
Pages : 240
Book Description
An insider's view on bringing extinct species back to life Could extinct species, like mammoths and passenger pigeons, be brought back to life? In How to Clone a Mammoth, Beth Shapiro, an evolutionary biologist and pioneer in ancient DNA research, addresses this intriguing question by walking readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used to resurrect the past. Considering de-extinction's practical benefits and ethical challenges, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.
A Clone of Your Own?
Author: Arlene Judith Klotzko
Publisher: Cambridge University Press
ISBN: 9780521852944
Category : Medical
Languages : en
Pages : 212
Book Description
A Clone of Your Own? by Arlene Judith Klotzko takes a close look at the inevitability of cloning, and the ethical, legal, and philosophical issues surrounding it.
Publisher: Cambridge University Press
ISBN: 9780521852944
Category : Medical
Languages : en
Pages : 212
Book Description
A Clone of Your Own? by Arlene Judith Klotzko takes a close look at the inevitability of cloning, and the ethical, legal, and philosophical issues surrounding it.
Scientific and Medical Aspects of Human Reproductive Cloning
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309076374
Category : Science
Languages : en
Pages : 295
Book Description
Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
Publisher: National Academies Press
ISBN: 0309076374
Category : Science
Languages : en
Pages : 295
Book Description
Human reproductive cloning is an assisted reproductive technology that would be carried out with the goal of creating a newborn genetically identical to another human being. It is currently the subject of much debate around the world, involving a variety of ethical, religious, societal, scientific, and medical issues. Scientific and Medical Aspects of Human Reproductive Cloning considers the scientific and medical sides of this issue, plus ethical issues that pertain to human-subjects research. Based on experience with reproductive cloning in animals, the report concludes that human reproductive cloning would be dangerous for the woman, fetus, and newborn, and is likely to fail. The study panel did not address the issue of whether human reproductive cloning, even if it were found to be medically safe, would beâ€"or would not beâ€"acceptable to individuals or society.
Regeneration: Stem Cells and Beyond
Author: Ellen Heber-Katz
Publisher: Springer Science & Business Media
ISBN: 364218846X
Category : Science
Languages : en
Pages : 202
Book Description
In this issue of Current Topics in Microbiology and Immunology the authors present a unique range of examples of the regenerative response and the role of stem cells from the amphibian to human. It seems that all roads lead to cells that have the plasticity to become something else, not only in the amphibian but also in the mammal.
Publisher: Springer Science & Business Media
ISBN: 364218846X
Category : Science
Languages : en
Pages : 202
Book Description
In this issue of Current Topics in Microbiology and Immunology the authors present a unique range of examples of the regenerative response and the role of stem cells from the amphibian to human. It seems that all roads lead to cells that have the plasticity to become something else, not only in the amphibian but also in the mammal.
Human Cloning
Author: United States. Congress. House. Committee on the Judiciary. Subcommittee on Crime
Publisher:
ISBN:
Category : Law
Languages : en
Pages : 98
Book Description
Publisher:
ISBN:
Category : Law
Languages : en
Pages : 98
Book Description
Reality Poems
Author: Isabella George
Publisher: First Edition Design Pub.
ISBN: 1506902731
Category : Poetry
Languages : en
Pages : 176
Book Description
Reality Poems (2016) is the revised edition of Isabella George's first e-book, Reality Poems of the Modern Day (2014). The title has been shortened, but content increased. In this revision, the poems are presented as more intense in-depth... and reveal an enriched ever-evolving awareness and determination to address issues more explicitly, without trepidation or regard to criticism. Reality Poems is a body of work that is now a collection of 70 short stories and poems of controversial issues relevant to modern culture. Each poem is a short story that creates mood and movement in a rhythmic lyrical contempo cadence aptly called Versery Rhymes™, some poems are written in an urban vernacular. Many stories in the collection of political and social issues are not usually topics of discourse in traditional poetry. These stories in atomic words are a clear and concise commentary on controversial issues not usually considered to be poetic. A range of poignant topics in the collection includes: Credit card entrapment, drug trafficking, interracial lovers, 9/11 conspiracy and other theories, the horrors of factory farming, death row, psychotic episodes, cigarette smoking, Lucifer Prince of the Air, strippers, the blues, ghosts, frankenfood, baptism, the death of one's mother, civil rights struggle of the '60's, sea level rise Miami and the Everglades, smoking weed, imagining the New World Order, aging cougars. Less poignant topics include: Teenage love crushes, forgetfulness, boys and their frogs, Barbie dolls, fashionistas, Hot Wheels, puppies, parakeets, heartbreak, Kool-Aid, the Brazilian Samba, gremlins, island living and many other topics of life.
Publisher: First Edition Design Pub.
ISBN: 1506902731
Category : Poetry
Languages : en
Pages : 176
Book Description
Reality Poems (2016) is the revised edition of Isabella George's first e-book, Reality Poems of the Modern Day (2014). The title has been shortened, but content increased. In this revision, the poems are presented as more intense in-depth... and reveal an enriched ever-evolving awareness and determination to address issues more explicitly, without trepidation or regard to criticism. Reality Poems is a body of work that is now a collection of 70 short stories and poems of controversial issues relevant to modern culture. Each poem is a short story that creates mood and movement in a rhythmic lyrical contempo cadence aptly called Versery Rhymes™, some poems are written in an urban vernacular. Many stories in the collection of political and social issues are not usually topics of discourse in traditional poetry. These stories in atomic words are a clear and concise commentary on controversial issues not usually considered to be poetic. A range of poignant topics in the collection includes: Credit card entrapment, drug trafficking, interracial lovers, 9/11 conspiracy and other theories, the horrors of factory farming, death row, psychotic episodes, cigarette smoking, Lucifer Prince of the Air, strippers, the blues, ghosts, frankenfood, baptism, the death of one's mother, civil rights struggle of the '60's, sea level rise Miami and the Everglades, smoking weed, imagining the New World Order, aging cougars. Less poignant topics include: Teenage love crushes, forgetfulness, boys and their frogs, Barbie dolls, fashionistas, Hot Wheels, puppies, parakeets, heartbreak, Kool-Aid, the Brazilian Samba, gremlins, island living and many other topics of life.
Advances in Plasma Cells in Health and Disease
Author: F. Eun-Hyung Lee
Publisher: Frontiers Media SA
ISBN: 2889662667
Category : Medical
Languages : en
Pages : 139
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Publisher: Frontiers Media SA
ISBN: 2889662667
Category : Medical
Languages : en
Pages : 139
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Nathan and Oski's Hematology and Oncology of Infancy and Childhood E-Book
Author: Stuart H. Orkin
Publisher: Elsevier Health Sciences
ISBN: 0323291775
Category : Medical
Languages : en
Pages : 3517
Book Description
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
Publisher: Elsevier Health Sciences
ISBN: 0323291775
Category : Medical
Languages : en
Pages : 3517
Book Description
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hematologic disorders, including newly recognized ones. - Develop a thorough, understanding of the underlying science of diseases through summaries of relevant pathophysiology balanced with clear, practical clinical guidance. Nathan and Oski's is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. - Quickly and effortlessly access the key information you need with the help of a consistent organization from chapter to chapter and from volume to volume. - Stay at the forefront of your field thanks to new and revised chapters covering topics such as paroxysmal nocturnal hemoglobinuria, lysosomal storage diseases, childhood genetic predisposition to cancer, and oncology informatics. - Learn about the latest breakthroughs in diagnosis and management, making this the most complete guide in pediatric hematology and oncology. - Discover the latest in focused molecularly targeted therapies derived from the exponential growth of knowledge about basic biology and genetics underlying the field. - Rely on it anytime, anywhere! Access the full text, images, and more at Expert Consult.
Recent Advances in γδ T Cell Biology: New Ligands, New Functions, and New Translational Perspectives
Author: Dieter Kabelitz
Publisher: Frontiers Media SA
ISBN: 2889197840
Category : Medicine (General)
Languages : en
Pages : 271
Book Description
Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional α/β T-cells, the available number of germline genes coding for T-cell receptor (TCR) variable elements of γδ T-cells is very small. Moreover, there is a prefential localization of γδ T-cells expressing given Vgamma and Vdelta genes in certain tissues. In humans, γδ T-cells expressing the Vg9Vd2-encoded TCR account for anywhere between 50 and >95% of peripheral blood γδ T-cells, whereas cells expressing non-Vd2 genes dominate in mucosal tissues. In mice, there is an ordered appearance of γδ T-cell „waves“ during embryonic development, resulting in preferential localization of γδ T-cells expressing distinct VgammaVdelta genes in the skin, the reproductive organs, or gut epithelia. The major function of γδ T-cells resides in local immunosurveillance and immune defense against infection and malignancy. This is supported by the identification of ligands that are selectively recognized by the γδ TCR. As an example, human Vgamma9Vdelta2 T-cells recognize phosphorylated metabolites („phosphoantigens“) that are secreted by many pathogens but can also be overproduced by tumor cells, providing a basis for a role of these γδ T-cells in both anti-infective and anti-tumor immunity. Similarly, the recognition of endothelial protein C receptor by human non-Vdelta2 γδ T-cells has recently been identified to provide a link for the role for such γδ T-cells in immunity against epithelial tumor cells and cytomegalovirus-infected endothelial cells. In addition to „classical“ functions such as cytokine production and cytotoxicity, recent studies suggest that subsets of γδ T-cells can exert additional functions such as regulatory activity and – quite surpisingly – „professional“ antigen-presenting capacity. It is currently not well known how this tremendous extent of functional plasticity is regulated and what is the extent of γδ TCR ligand diversity. Due to their non-MHC-restricted recognition of unusual stress-associated ligands, γδ T-cells have raised great interest as to their potential translational application in cell-based immunotherapy. Topics of this Research Focus include: Molecular insights into the activation and differentiation requirements of γδ T-cells, role of pyrophosphates and butyrophilin molecules for the activation of human γδ T-cells, role of γδ T-cells in tumor immunity and in other infectious and non-infectious diseases, and many others. We are most grateful to all colleagues who agreed to write a manuscript. Thanks to their contributions, this E-book presents an up-to-date overview on many facets of the still exciting γδ T-cells. Dieter Kabelitz & Julie Déchanet-Merville
Publisher: Frontiers Media SA
ISBN: 2889197840
Category : Medicine (General)
Languages : en
Pages : 271
Book Description
Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional α/β T-cells, the available number of germline genes coding for T-cell receptor (TCR) variable elements of γδ T-cells is very small. Moreover, there is a prefential localization of γδ T-cells expressing given Vgamma and Vdelta genes in certain tissues. In humans, γδ T-cells expressing the Vg9Vd2-encoded TCR account for anywhere between 50 and >95% of peripheral blood γδ T-cells, whereas cells expressing non-Vd2 genes dominate in mucosal tissues. In mice, there is an ordered appearance of γδ T-cell „waves“ during embryonic development, resulting in preferential localization of γδ T-cells expressing distinct VgammaVdelta genes in the skin, the reproductive organs, or gut epithelia. The major function of γδ T-cells resides in local immunosurveillance and immune defense against infection and malignancy. This is supported by the identification of ligands that are selectively recognized by the γδ TCR. As an example, human Vgamma9Vdelta2 T-cells recognize phosphorylated metabolites („phosphoantigens“) that are secreted by many pathogens but can also be overproduced by tumor cells, providing a basis for a role of these γδ T-cells in both anti-infective and anti-tumor immunity. Similarly, the recognition of endothelial protein C receptor by human non-Vdelta2 γδ T-cells has recently been identified to provide a link for the role for such γδ T-cells in immunity against epithelial tumor cells and cytomegalovirus-infected endothelial cells. In addition to „classical“ functions such as cytokine production and cytotoxicity, recent studies suggest that subsets of γδ T-cells can exert additional functions such as regulatory activity and – quite surpisingly – „professional“ antigen-presenting capacity. It is currently not well known how this tremendous extent of functional plasticity is regulated and what is the extent of γδ TCR ligand diversity. Due to their non-MHC-restricted recognition of unusual stress-associated ligands, γδ T-cells have raised great interest as to their potential translational application in cell-based immunotherapy. Topics of this Research Focus include: Molecular insights into the activation and differentiation requirements of γδ T-cells, role of pyrophosphates and butyrophilin molecules for the activation of human γδ T-cells, role of γδ T-cells in tumor immunity and in other infectious and non-infectious diseases, and many others. We are most grateful to all colleagues who agreed to write a manuscript. Thanks to their contributions, this E-book presents an up-to-date overview on many facets of the still exciting γδ T-cells. Dieter Kabelitz & Julie Déchanet-Merville