Epilipidome as a New Level of Cellular Regulation PDF Download

Author: Maria Fedorova
Publisher: Frontiers Media SA
ISBN: 2889760073
Category : Medical
Languages : en
Pages : 136

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Author: Nenad Blau
Publisher: Springer
ISBN: 3642403379
Category : Medical
Languages : en
Pages : 880

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Book Description
This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of metabolic diseases. The clinical and laboratory data characteristic of rare metabolic conditions can be bewildering for both clinicians and laboratory personnel. Reference laboratory data are scattered, and clinical descriptions may be obscure. The Physician’s Guide documents the features of more than five hundred conditions, grouped according to type of disorder, organ system affected (e.g. liver, kidney, etc) or phenotype (e.g. neurological, hepatic, etc). Relevant clinical findings are provided and pathological values for diagnostic metabolites highlighted. Guidance on appropriate biochemical genetic testing is provided. Established experimental therapeutic protocols are described, with recommendations on follow-up and monitoring. The authors are acknowledged experts, and the book will be a valuable desk reference for all who deal with inherited metabolic diseases.

Author: Raúl Alvarez-Venegas
Publisher: Springer
ISBN: 3319079719
Category : Science
Languages : en
Pages : 158

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Book Description
Over the past decades, chromatin remodelling has emerged as an important regulator of gene expression and plant defense. This book provides a detailed understanding of the epigenetic mechanisms involved in plants of agronomic importance. The information presented here is significant because it is expected to provide the knowledge needed to develop in the future treatments to manipulate and selectively activate/inhibit proteins and metabolic pathways to counter pathogens, to treat important diseases and to increase crop productivity. New approaches of this kind and the development of new technologies will certainly increase our knowledge of currently known post-translational modifications and facilitate the understanding of their roles in, for example, host-pathogen interactions and crop productivity. Furthermore, we provide important insight on how the plant epigenome changes in response to developmental or environmental stimuli, how chromatin modifications are established and maintained, to which degree they are used throughout the genome, and how chromatin modifications influence each another.

Author: Catherine Shanahan, M.D.
Publisher: Flatiron Books
ISBN: 1250309514
Category : Health & Fitness
Languages : en
Pages : 320

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Book Description
A proven plan to optimize your health by reclaiming your natural ability to burn body fat for fuel The ability to use body fat for energy is essential to health—but over decades of practice, renowned family physician Catherine Shanahan, M.D., observed that many of her patients could not burn their body fat between meals, trapping them in a downward spiral of hunger, fatigue, and weight gain. In The Fatburn Fix, Dr. Shanahan shows us how industrially produced vegetable oils accumulate in our body fat and disrupt our body’s energy-producing systems, driving food addictions that hijack our moods and habits while making it nearly impossible to control our weight. To reclaim our health, we need to detoxify our body fat and help repair our “fatburn” capabilities. Dr. Shanahan shares five important rules to fix your fatburn: 1) Eat natural fats, not vegetable oils. 2) Eat slow-digesting carbs, not starchy carbs or sweets. 3) Seek salt. 4) Drink plenty of water. 5) Supplement with vitamins and minerals. She then provides a revolutionary, step-by-step plan to help reboot your fatburn potential in as little as two weeks. This customizable two-phase plan is widely accessible, easy to follow, and will appeal to the full spectrum of diet ideologies, from plant-based to carnivore to keto and beyond. By making a few changes to what you eat and when, you will lose unwanted weight and restore your body’s ability to store and release energy. With The Fatburn Fix, Dr. Shanahan shows how regaining your fatburn is the key to effortless weight loss and a new, elevated life, paving the way to abundant energy and long-term health and happiness.

Author: Seema Puri
Publisher: Nova Science Publishers
ISBN: 9781685070670
Category : Education
Languages : en
Pages : 0

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Book Description
This publication focuses on the situation, opportunities and challenges in providing children an optimal environment for growth and development in India. Issues like early childhood care and education, nutrition opportunities through infancy, and physical and mental health of children are explored. An attempt has also been made to shed light on emerging challenges such as child development amidst pandemics like COVID-19, the increasing influence of media in the child's development, and tackling the triple burden of malnutrition. Implementation of related policies and programs, both by governmental and non-governmental agencies, has been detailed for lessons learnt. The contributors to this edition are experienced researchers, practitioners, and academicians with extensive work in their respective areas of expertise. There is a good representation from different parts of the country which gives the reader a flavour of the regional diversity while dealing with children and their issues. The book provides a comprehensive updated reference for the scientific community. In addition, students and researchers in public health, social work, epidemiology, community medicine, public nutrition, human development, anthropology and sociology are the target audience. Stakeholders involved in policy planning, program implementation and advocacy will also benefit from this publication.

Author: Etsuo Niki
Publisher: Royal Society of Chemistry
ISBN: 1788017331
Category : Medical
Languages : en
Pages : 235

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Book Description
Vitamin E was discovered in 1922 by Evans and Bishop as an essential micronutrient for reproduction in rats. The active substance was isolated in 1936 by Evans and was named tocopherol, although the tocopherols and tocotrienols are actually a group of eight isomeric molecules that are characterized by a chromanol ring structure and a side chain. Providing an overview of the state-of-the-art of the chemistry of vitamin E, this book reflects the issues stemming from the complexity of the role and actions in vivo as well as in vitro. It summarizes information on the properties and function of vitamin E, the current understanding of the advantages and limitations of it, and also its application in promotion of health and prevention of diseases. Based on sound, solid scientific evidence, this is a timely addition to the literature as the centennial anniversary of the discovery of this important vitamin approaches.

Author: J. Robin Harris
Publisher: Springer
ISBN: 9811336814
Category : Medical
Languages : en
Pages : 502

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Book Description
This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.

Author: Kenneth A. Ellenbogen
Publisher: Elsevier
ISBN: 9780323987110
Category : Medical
Languages : en
Pages : 240

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Book Description
In this issue of Cardiac Electrophysiology Clinics, guest editors Drs. Kenneth A. Ellenbogen, Pugazhendhi Vijayaraman, and Santosh Padala bring their considerable expertise to the topic of Advances in Physiologic Pacing (such as dual-chamber (DDD and DDDR) and atrium-based pacing (AAI and AAIR) in contrast to ventricle-based pacing (VVI and VVIR). Top experts in the field cover key topics such as what we have learned from computer modeling of hemodynamics and LV pacing; troubleshooting the pacemaker EKG in patients with conduction system pacing; what intracardiac tracings have taught us about LBBB; multisite pacing in CRT; and more. Contains 20 relevant, practice-oriented topics including basic principles of hemodynamics during pacing; pacing optimized by dP/dt; optimization of CRT: Q-LV; programming algorithms for CRT; and more. Provides in-depth clinical reviews on physiologic pacing, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Author: A Nicolaou
Publisher: Oily Press
ISBN: 9780953194971
Category : Science
Languages : en
Pages : 0

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Book Description
In Bioactive lipids, Anna Nicolaou and George Kokotos have brought together an international team of authors to discuss the nomenclature, structures, biochemistry, pharmacology and recent developments in the main classes of bioactive lipids. These lipids are essential components of the cell membrane and play many dynamic roles in mediating and controlling a wide array of cellular activities including membrane structure and organization, metabolic and gene regulation, protein structure and function, energy production, and signalling pathways. The lipid interests of scientists in the pharmaceutical and food industries are converging as the broader significance of bioactive lipids is increasingly recognized. Lipids and lipid-metabolizing enzymes are targeted for the development of new drugs. Meanwhile, functional foods, nutraceuticals and supplements already have lipids as major active ingredients. The food industry will progress from simply using lipids as ingredients, to the formulation of products that influence the synthesis, metabolism and effects of bioactive lipids in the body. These advances in applied lipid biochemistry will build on the fundamental research of lipid scientists in universities worldwide, such as those scientists contributing to Bioactive lipids.

Author: Markus R. Wenk
Publisher: Springer
ISBN: 9789400774667
Category : Medical
Languages : en
Pages : 0

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Book Description
The Encyclopedia of Lipidomics will present a complete overview of the field from fundamentals to new discoveries and from concepts, theories and experimental techniques to clinical and industrial applications. The book will develop with the active involvement of a strong editorial board comprised of leaders from the field. The Encyclopedia of Lipidomics intends to be a comprehensive reference resource serving to bridge the gap between clinical and basic science investigators and provide authoritative and digested information to students, scientists as well as non specialists. The book will have an edge over protocol type of works and databases in terms of having wider coverage through rigorous essays on terms, concepts, experimental and analytical techniques, applications and new challenges. Since lipidomics has strong linkages with several of the other biomedical and life sciences disciplines, the proposed encyclopedia will have a wide audience including graduate students, researchers and different levels of scientists in biomedicine, cellular and molecular biology, bioengineering, physiological and biochemistry, and pharmacology across both academia and industry.