Author: Gertz I. Likhtenshtein Publisher: Springer ISBN: 9783031515514 Category : Science Languages : en Pages : 0
Book Description
This book examines enzymatic reactions from the standpoint of physical chemistry. An introductory chapter gives a brief overview of the role of enzymes in metabolism, biotechnology and medicine, while describing the framework for chemical mimicry of enzyme reactions. Subsequent chapters of the book are devoted to a general overview of vital enzyme processes, methods of enzyme kinetic reactions, the theory of elementary mechanisms, oriental, dynamic and polar factors affecting enzyme catalysts, as well as the current status and prospects of enzyme chemical modeling. The book gives particular attention to chemical reactions highly important in modern research efforts, such as the conversion of light energy into chemical energy with a high quantum yield, photooxidation of water, reduction of atmospheric nitrogen, and utilization of carbon dioxide in ambient conditions. The book is intended for scientists working on enzyme catalysis and the adjacent areas such as chemical modeling of biological processes, homogeneous catalysis, biomedical research, biotechnology and bioengineering. In addition, it can serve as secondary instructional material for graduate and undergraduate students of chemistry, medicine, biochemistry, biophysics, biophysiology, and bioengineering.
Author: Judith Klinman Publisher: Springer ISBN: 3642389627 Category : Science Languages : en Pages : 217
Book Description
Christopher M. Cheatum and Amnon Kohen, Relationship of Femtosecond–Picosecond Dynamics to Enzyme-Catalyzed H-Transfer. Cindy Schulenburg and Donald Hilvert, Protein Conformational Disorder and Enzyme Catalysis. A. Joshua Wand, Veronica R. Moorman and Kyle W. Harpole, A Surprising Role for Conformational Entropy in Protein Function. Travis P. Schrank, James O. Wrabl and Vincent J. Hilser, Conformational Heterogeneity Within the LID Domain Mediates Substrate Binding to Escherichia coli Adenylate Kinase: Function Follows Fluctuations. Buyong Ma and Ruth Nussinov, Structured Crowding and Its Effects on Enzyme Catalysis. Michael D. Daily, Haibo Yu, George N. Phillips Jr and Qiang Cui, Allosteric Activation Transitions in Enzymes and Biomolecular Motors: Insights from Atomistic and Coarse-Grained Simulations. Karunesh Arora and Charles L. Brooks III, Multiple Intermediates, Diverse Conformations, and Cooperative Conformational Changes Underlie the Catalytic Hydride Transfer Reaction of Dihydrofolate Reductase. Steven D. Schwartz, Protein Dynamics and the Enzymatic Reaction Coordinate.
Author: Gertz I. Likhtenshtein Publisher: Springer Science & Business Media ISBN: 0306481103 Category : Science Languages : en Pages : 239
Book Description
"This book is a view of enzyme catalysis by a physico-chemist with long-term experience in the investigation of structure and action mechanism of biological catalysts. This book is not intended to provide an exhaustive survey of each topic but rather a discussion of their theoretical and experimental background, and recent developments. The literature of enzyme catalysis is so vast and many scientists have made important contribution in the area, that it is impossible in the space allowed for this book to give a representative set of references. The author has tried to use reviews, and general principles of articles. He apologizes to those he has not been able to include. . ... The monograph is intended for scientists working on enzyme catalysis and adjacent areas such as chemical modeling of biological processes, homogeneous catalysis, biomedical research and biotechnology. The book can be use as a subsidiary manual for instructors, graduate and undergraduate students of university biochemistry and chemistry departments."--Pages ix-x.
Author: Karlheinz Drauz Publisher: John Wiley & Sons ISBN: 3527325476 Category : Science Languages : en Pages : 2143
Book Description
This comprehensive three-volume set is the standard reference in the field of organic synthesis, catalysis and biocatalysis. Edited by a highly experienced and highly knowledgeable team with a tremendous amount of experience in this field and its applications, this edition retains the successful concept of past editions, while the contents are very much focused on new developments in the field. All the techniques described are directly transferable from the lab to the industrial scale, making for a very application-oriented approach. A must for all chemists and biotechnologists.
Author: Anthony John Kirby Publisher: Royal Society of Chemistry ISBN: 0854041753 Category : Science Languages : en Pages : 286
Book Description
Designing artificial systems with catalytic efficiencies to rival those of natural enzymes is one of the great challenges facing science today. This introduction to the exciting area of artificial enzymes is suitable for both students and more senior researchers.
Author: A. Cooper Publisher: Springer Science & Business Media ISBN: 1475716079 Category : Science Languages : en Pages : 479
Book Description
This volume represents the proceedings of a NATO Advanced Studies Instituteheld near Barga (Italy), July 11-23, 1988, involving over 90 participants from more than twelve countries of Europe, North America and elsewhere. It was not our intention at this meeting to present a complete up-to-the-minute review of current research in enzyme catalysis but t·ather, in accord wi th the intended spiri t of NATO ASis, to gi ve an opportunity for advanced students and researchers in a wide variety of disciplines to meet tagether and study the problern from different points of view. Hence the lectures cover topics rauging from the purely theoretical aspects of chemical reaction kinetics in condensed matter through practical experimental approaches to enzyme structure, dynamics and mechanism, including the new experimental opportunities arising from genetic engineering techniques. Our approachwas unashamedly physical, both because the more biochemical aspects of enzymology are amply covered elsewhere and because progress in our understanding and application of the molecular basis of enzymic processes must ultimately come from advances in physical knowledge. We tried to cover as wide a spectrum as possible, and succeeded in gathering an expert and enthusiastic team of speakers, but there . are some inevitable omissions. In particular, and with hindsight, our discussions might have been enriched by more detailed coverage of general aspects of chemical catalysis - but readers requiring this background should find adequate references herein.
Author: Valerian T. D'Souza Publisher: CRC Press ISBN: 9780849368233 Category : Science Languages : en Pages : 232
Book Description
This volume grew out of a symposium organized by the students of Professor Myron L. Bender. His research focused on the mechanisms of enzymatic catalysis and was instrumental in showing that enzymes do not possess magical powers to accelerate reactions a trillion times on an average, but follow simple rules of chemistry. A group of scientists who were trained by Bender have contributed some of their work to this book to pay homage to their mentor. The range of topics covered is such that researchers and industry with interest in biological chemistry will gain knowledge from the advances being made in related fields. The book shows organic chemists what advances have taken place in biological chemistry and biochemists will discover how principles of organic chemistry can be applied to reveal the powers of enzymatic catalysis.
Author: Eduardo Garcia-Junceda Publisher: John Wiley & Sons ISBN: 3527623396 Category : Science Languages : en Pages : 256
Book Description
The first comprehensive coverage of this unique and interdisciplinary field provides a complete overview, covering such topics as chemoenzymatic synthesis, microbial production of DNA building blocks, asymmetric transformations by coupled enzymes and much more. By combining enzymatic and synthetic organic steps, the use of multi-enzyme complexes and other techniques opens the door to reactions hitherto unknown, making this monograph of great interest to biochemists, organic chemists, and chemists working with/on organometallics, as well as catalytic chemists, biotechnologists, and those working in the pharmaceutical and fine chemical industries.
Author: Wolf-Dieter Fessner Publisher: John Wiley & Sons ISBN: 9783527320714 Category : Science Languages : en Pages : 406
Book Description
Das Gesamtgebiet der Biokatalyse mit allen seinen Facetten -- Mikrobiologie, Enzymologie, Molekularbiologie, Strukturbiologie, organische Chemie -- wird in diesem interdisziplinär angelegten Werk beleuchtet; insbesondere geht es um enzymatische Katalysen und Ganzzell-Katalysen. Ein Schwerpunkt liegt dabei auf der Entwicklung hochselektiver, umweltfreundlicher Prozesse zur Synthese wichtiger Verbindungsklassen.
Author: Publisher: Academic Press ISBN: 0080865968 Category : Technology & Engineering Languages : en Pages : 471
Book Description
The remarkable expansion of information leading to a deeper understanding of enzymes on the molecular level necessitated the development of this volume which not only introduces new topics to The Enzymes series but presents new information on some covered in Volume I and II of this edition.
Author: Gertz I. Likhtenshtein
Author: Judith Klinman
Author: Gertz I. Likhtenshtein
Author: Karlheinz Drauz
Author: Anthony John Kirby
Author: A. Cooper
Author: Valerian T. D'Souza
Author: Eduardo Garcia-Junceda
Author: Wolf-Dieter Fessner
Author: