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Author: Alexander Lyubimov Publisher: Anchor Books ISBN: 9781118149751 Category : Drug interactions Languages : en Pages : 631
Book Description
This multi-volume, state-of-the-art encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. Methods and detailed protocols describing how to perform studies of metabolism and drug interactions are presented in one of the volumes. All aspects of drug metabolism and interactions in silico, in laboratory animals and in humans, are backed with a range of examples. This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians including practitioners and physicians.
Author: Alexander Lyubimov Publisher: Anchor Books ISBN: 9781118149751 Category : Drug interactions Languages : en Pages : 631
Book Description
This multi-volume, state-of-the-art encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. Methods and detailed protocols describing how to perform studies of metabolism and drug interactions are presented in one of the volumes. All aspects of drug metabolism and interactions in silico, in laboratory animals and in humans, are backed with a range of examples. This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians including practitioners and physicians.
Author: Publisher: Wiley ISBN: 9781118180037 Category : Medical Languages : en Pages : 0
Book Description
The ideal place to begin researching any question involving drug metabolism and interactions The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field. By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human models Effects of both genetic and non-genetic factors on drug metabolism Relationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safety Examples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humans Methods and protocols enabling readers to perform seamless studies of metabolism and drug interactions All articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature. The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.
Author: Publisher: Wiley ISBN: 9781118180013 Category : Medical Languages : en Pages : 836
Book Description
"This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher.
Author: Alexander Lyubimov Publisher: Anchor Books ISBN: 9781118149744 Category : Drug interactions Languages : en Pages : 992
Book Description
The ideal place to begin researching any question involving drug metabolism and interactions The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction within the human body. This six-volume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written and edited by leading international experts in the field. By collecting and reviewing the current literature in the field in one expertly organized work, this encyclopedia is the ideal place to begin researching any question involving drug metabolism and interactions. Readers will find such important topics and working tools as: Inhibited or induced enzymes and their impact on drug toxicity and altered response in both animal and human models Effects of both genetic and non-genetic factors on drug metabolism Relationships between a drug metabolism, its activation or inactivation, and a drug's potential toxicity/safety Examples demonstrating all aspects of drug metabolism and interactions in silico, in vitro, in laboratory animals, and in humans Methods and protocols enabling readers to perform seamless studies of metabolism and drug interactions All articles are based on recent findings and standards of practice. By reviewing and contextualizing the current literature, the authors offer new perspectives on our current state of knowledge as well as future directions for research in drug metabolism and interactions. References at the end of each article serve as a gateway to the literature. The Encyclopedia of Drug Metabolism and Interactions is recommended for researchers, physicians, and students at all levels. It introduces the basics to novices and explores the latest science and applications for more experienced investigators.
Author: Publisher: Wiley ISBN: 9780470450154 Category : Medical Languages : en Pages : 0
Book Description
“This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Author: Publisher: Wiley ISBN: 9780470450154 Category : Medical Languages : en Pages : 4736
Book Description
“This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Author: Publisher: Wiley ISBN: 9780470450154 Category : Medical Languages : en Pages : 4736
Book Description
“This one-stop reference brings together information scattered throughout the literature, and it involved the efforts of 270 expert authors from 16 countries — a global endeavor accomplished under the leadership of editor Alexander Lyubimov.” –Book News Inc., February 2013 The Encyclopedia of Drug Metabolism and Interactions provides essential support during all phases of drug development, from drug design to drug action and interaction in patients. This multivolume work covers both preclinical and clinical aspects of drug metabolism and interactions. It also provides a wealth of toxicological, regulatory, and marketing information, all written by leading international experts in the field. Using this reference you’ll discover: • Enzymes that can be inhibited or induced and their impact on drug toxicity and altered response in both animal and human models • Effect of genetic differences and non-genetic factors on drug metabolism • Balance among drug metabolism, its inactivation/activation, and its potential toxicity • Examples demonstrating all aspects of drug metabolism and interactions in silico, in laboratory animals, and in humans • Methods and detailed protocols enabling you to perform seamless studies of metabolism and drug interactions This reference is essential for researchers interested in all aspects of drug development, and chemists, pharmacologists, pharmaceutical specialists, toxicologists, molecular toxicologists, and clinicians, including practitioners and physicians. Enjoy the Online Advantage... The Encyclopedia of Drug Metabolism and Interactions is available online now. For further information visit wileyonlinelibrary.com/ref/lyubimov
Author: Publisher: ISBN: Category : Languages : en Pages :
Book Description
This multi-volume encyclopedia discusses all preclinical, clinical, toxicological, regulatory and marketing perspectives of drug metabolism and interactions. The various types of enzymes that can be inhibited or induced and their impact on drug toxicity and altered response are covered both for animal models and humans"--Provided by publisher
Author: Corina Ionescu Publisher: Springer Science & Business Media ISBN: 9781402041419 Category : Medical Languages : en Pages : 444
Book Description
Drug Metabolism: Current Concepts provides a comprehensive understanding of the processes that take place following ingestion of a medicinal agent or xenobiotic, with an emphasis on the crucial role of metabolism (biotransformation). How a sound knowledge of these phenomena is incorporated into the design of effective new drug candidates is also explained. The user-friendly text focuses on concepts rather than extraneous details and is supported by many illustrated examples of biotransformations as well as frequent references to current critical reviews and articles highlighting the nature of research objectives in this vibrant area of medicinal development. The final topic on strategies for drug design relies on the background provided by the rest of the book. This book is ideally suited as an advanced text for courses in drug metabolism for students of medicine, pharmacy, pharmacology, biochemistry; and for courses in drug design and drug delivery for students of medicinal chemistry. It is also appropriate for professional seminars or courses that relate to the fate of a drug in the body, drug interactions, adverse reactions and drug design.
Author: Alan Talevi Publisher: Springer Nature ISBN: 3030848604 Category : Medical Languages : en Pages : 1209
Book Description
The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties
Author: Alexander Lyubimov
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Author: Corina Ionescu
Author: Alan Talevi